The vast distribution and long duration of the Late Mesozoic magmatism in the eastern part of South China presents a unique case in the world. This offers a natural laboratory to study the process of magma genesis, the magma emplacement mode, the relationship between magmatism and tectonics, the geodynamic role on the magma emplacement and lithospheric evolution. Since 50's, particularly 90's of the last century, geoscientists have made important efforts in geological cartography and carried out numerous studies with remarkable scientific achievements, building a solid background to understand the tectonic evolution of the South China Block (SCB). However, certain fundamental questions mentioned above remain unsolved and/or are in hot debate. In order to make progress in these scientific issues, we have carried out in a multi-disciplinary study in the Late Mesozoic Qingyang-Jiuhua massif, Hengshan massif and Fujian coastal zone according to their distance with respect to the paleo subduction zone of the Paleo-Pacific plate, the ages of granitic massifs and related tectonics, including field observation on the structure geology, micro-observation on thin section, U-Pb dating on monazite, AMS, paleomagnetism, gravity modeling and P condition concern the granite emplacement. In the view of deformation in these granitic massifs and their country rocks, mode and influence of regional tectonics on the emplacement, though each studied zone reveals its distinguished characteristics, they show some intrinsic and common relationships between them. With our new results and integrating previous data, in this thesis, we discuss the tectonic context of emplacement of these Late Mesozoic magmatic massifs and the geodynamic evolution of the SCB., We propose a 3-step geodynamic model: (1) during 145-130 Ma period, the Paleo-Pacific plate subducted northwestwardly, the West Philippines micro-continent, approaching to SCB, important subduction-related arc volcanism was produced in the coastal areas of Southeast China coast (Zhejiang-Fujian-Guangdong), forming a back-arc extension tectonic system in SCB; (2) during 130-110 Ma period, due to the collision between the West Philippines microcontinent and SCB, the compressional tectonic structures were developed in the Changle-Na'ao coastal zone, producing ductile deformation zones. However, the inland of the eastern part of SCB was under a NW-SE extensional tectonic regime; (3) during 105-90 Ma period, a new subduction zone was developed in the SE flank of the West Philippines micro-continent, the subducting slab reached the Changle-Nan'ao tectonic belt, with the possible break-off of slab, the asthenospheric ascent was responsible for the important emplacement of plutonic massifs and dykes. The tectonics of the eastern part of SCB was characterized by a general extensional system in this period. This tectonic pattern has been significantly disturbed by the Oligocene-Eocene opening of the South China sea,and the Miocene shortening of the SCB margin in Taiwan. Of course, this model should be improved by more geological, geophysical and geochemical investigations.