Cell and Molecular Biology of the Ear

Cell and Molecular Biology of the Ear
Author: David J. Lim
Publisher: Springer Science & Business Media
Total Pages: 274
Release: 2013-11-11
Genre: Medical
ISBN: 1461542235

Dr. Howard House, founder of the House Ear Institute and House Ear Clinic often uses the analogy of planting a seed when referring to establishing the House Ear Institute in 1946. Two grateful patients of Dr. House put forth the idea that his knowledge and innovative skills could be used to expand the understanding of hearing impairment and its treatment. Those two early patients provided the "seed money" to begin the Institute. Since that time, the growth has been phenomenal from a one-man laboratory to a multidisciplinary facility boasting over 175 scien tists, physicians, and support staff, all dedicated to the advancement of otologic research and education. Six years ago after a half-century of remarkable success with prosthetic and device research, the Institute began cultivating a new field of endeavor-cell and molecular biology. Don Nielsen, then the Institute's Executive Vice President for Research and Scientific Director, began exploring the potential for hair cell regen eration and presented his ideas to the Board of Trustees. For a period of six months, we did a lot of fact finding to assess what role the Institute might take in this excit ing new field.

Development of Auditory and Vestibular Systems

Development of Auditory and Vestibular Systems
Author: Raymond Romand
Publisher: Academic Press
Total Pages: 563
Release: 2014-05-23
Genre: Science
ISBN: 0124081088

Development of Auditory and Vestibular Systems fourth edition presents a global and synthetic view of the main aspects of the development of the stato-acoustic system. Unique to this volume is the joint discussion of two sensory systems that, although close at the embryological stage, present divergences during development and later reveal conspicuous functional differences at the adult stage. This work covers the development of auditory receptors up to the central auditory system from several animal models, including humans. Coverage of the vestibular system, spanning amphibians to effects of altered gravity during development in different species, offers examples of the diversity and complexity of life at all levels, from genes through anatomical form and function to, ultimately, behavior. The new edition of Development of Auditory and Vestibular Systems will continue to be an indispensable resource for beginning scientists in this area and experienced researchers alike. - Full-color figures illustrate the development of the stato-acoustic system pathway - Covers a broad range of species, from drosophila to humans, demonstrating the diversity of morphological development despite similarities in molecular processes involved at the cellular level - Discusses a variety of approaches, from genetic-molecular biology to psychophysics, enabling the investigation of ontogenesis and functional development

Development of the Inner Ear

Development of the Inner Ear
Author: Matthew Kelley
Publisher: Springer Science & Business Media
Total Pages: 250
Release: 2006-03-04
Genre: Science
ISBN: 0387306781

The Springer Handbook of Auditory Research presents a series of compreh- sive and synthetic reviews of the fundamental topics in modern auditory - search. The volumes are aimed at all individuals with interests in hearing research including advanced graduate students, postdoctoral researchers, and clinical investigators. The volumes are intended to introduce new investigators to important aspects of hearing science and to help established investigators to betterunderstandthefundamentaltheoriesanddatain?eldsofhearingthatthey may not normally follow closely. Each volume presents a particular topic comprehensively, and each servesas a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in peer-reviewed journals. The volumes focus on topics that have developed a solid data and conceptual foundation rather than on those for which a literature is only beginning to develop. New research areas will be covered on a timely basis in the series as they begin to mature. Eachvolumeintheseriesconsistsofafewsubstantialchaptersonaparticular topic. In some cases, the topics will be ones of traditional interest for which there is a substantial body of data and theory, such as auditory neuroanatomy (Vol. 1) and neurophysiology (Vol. 2). Other volumes in the series deal with topics that have begun to mature more recently, suchasdevelopment,plasticity, and computational models of neural processing. In many cases, the series - itorsarejoinedbyaco-editorhavingspecialexpertiseinthetopicofthevolume.

Compendium of Histology

Compendium of Histology
Author: Anders Rehfeld
Publisher: Springer
Total Pages: 670
Release: 2017-09-07
Genre: Medical
ISBN: 3319418734

This book has been designed to help medical students succeed with their histology classes, while using less time on studying the curriculum. The book can both be used on its own or as a supplement to the classical full-curriculum textbooks normally used by the students for their histology classes. Covering the same curriculum as the classical textbooks, from basic tissue histology to the histology of specific organs, this book is formatted and organized in a much simpler and intuitive way. Almost all text is formatted in bullets or put into structured tables. This makes it quick and easy to digest, helping the student get a good overview of the curriculum. It is easy to locate specific information in the text, such as the size of cellular structures etc. Additionally, each chapter includes simplified illustrations of various histological features. The aim of the book is to be used to quickly brush up on the curriculum, e.g. before a class or an exam. Additionally, the book includes guides to distinguish between the different histological tissues and organs that can be presented to students microscopically, e.g. during a histology spot test. This guide lists the specific characteristics of the different histological specimens and also describes how to distinguish a specimen from other similar specimens. For each histological specimen, a simplified drawing and a photomicrograph of the specimen, is presented to help the student recognize the important characteristics in the microscope. Lastly, the book contains multiple “memo boxes” in which parts of the curriculum are presented as easy-to-remember mnemonics.

Vertebrate Hair Cells

Vertebrate Hair Cells
Author: Ruth Anne Eatock
Publisher: Springer Science & Business Media
Total Pages: 478
Release: 2006-01-04
Genre: Medical
ISBN: 9780387952024

Vertebrate Hair Cells provides a current overview of the mechanosensory receptor cells of the vertebrate inner ear. Each chapter is written by experimentalists active in exploring a particular set of questions in an aspect of hair cell function, including development, transduction, and synaptic transmission. Experimental approaches described include molecular, genetic, ultrastructural, biophysical and computational. Thus, each chapter covers not just what we know, but how we have learned it and the implications for future work. The experimental focus differentiates this book from general textbooks and targets an advanced audience, from senior undergraduates through to scientists in the field of hair cell research.

The Neuron

The Neuron
Author: Irwin B. Levitan
Publisher: Oxford University Press, USA
Total Pages: 640
Release: 2002
Genre: Language Arts & Disciplines
ISBN: 9780195145236

Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.

Hearing Loss: Mechanisms, Prevention and Cure

Hearing Loss: Mechanisms, Prevention and Cure
Author: Huawei Li
Publisher: Springer
Total Pages: 182
Release: 2019-03-26
Genre: Medical
ISBN: 9811361231

This book systematically discusses the pathogenesis, prevention, and the current and potential clinical treatment of hearing loss, as well as the latest advances in hearing research. Hearing loss is a prevalent sensory disorder, which according to a 2015 World Health Organization (WHO) report affected 9% of the global population in 2015. As populations continue to age, more and more people are suffering from the condition, with 60% of those aged between 65 and 75 affected. Hearing loss seriously affects patients’ ability to work ability and quality of life, and as such deafness has become an increasingly urgent social problem around the globe. Sensorineural hearing loss is mainly caused by damage to the hair cells (HCs), and the subsequent loss of spiral ganglion neurons (SGNs). Damage to the HCs in the inner ear can result from exposure to loud noises and environmental and chemical toxins as well as genetic disorders, aging, and certain medications. This book provides ENT specialists and researchers, as well as individuals affected a comprehensive introduction to the field of hearing loss.

Cochlear Mechanics

Cochlear Mechanics
Author: Frank Böhnke
Publisher: S. Karger AG (Switzerland)
Total Pages: 0
Release: 1999
Genre: Cochlea
ISBN: 9783805569880

This special issue collects our current knowledge of the mechanical processing of acoustic signals by the cochlea and its containing structures. Many workers in diverse disciplines in otology use the facts from cochlear mechanics for the interpretation of their results. Presented here for the first time is the development of a three-dimensional mechanical model of the curved cochlea including fluid-structure couplings. An important approach for future cochlear modeling is shown by the provision of geometrical data for the input of three-dimensional finite element models by microtomographic imaging. A remarkable article tries to demonstrate a connection between outer hair cell mechanics and the complex phenomenon of tinnitus and will be of special interest for stress engineers. Owing to its strong interdisciplinarity, this issue is not only intended for biophysicists, ENT clinicians and audiologists but also for radiologists, biomechanical engineers and computer engineers.

Cell Cycle Oscillators

Cell Cycle Oscillators
Author: Amanda S. Coutts
Publisher: Humana
Total Pages: 0
Release: 2015-08-09
Genre: Science
ISBN: 9781493929566

​ This volume brings together a unique collection of protocols that cover standard, novel, and specialized techniques. Cell Cycle Oscillators: Methods and Protocols guides readers through recent progress in the field from both holistic and reductionist perspectives, providing the latest developments in molecular biology techniques, biochemistry, and computational analysis used for studying oscillatory networks. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cell Cycle Oscillators: Methods and Protocols will serve as an invaluable reference to gain further insight into the complex and incompletely understood processes that are involved in the cell cycle and its regulation by oscillatory networks.