Cytokines, Novel Cell Death Models and Pathways in Cardiovascular Diseases

Cytokines, Novel Cell Death Models and Pathways in Cardiovascular Diseases
Author: Yuli Huang
Publisher: Frontiers Media SA
Total Pages: 98
Release: 2023-09-26
Genre: Medical
ISBN: 2832534414
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Cytokines are soluble proteins secreted by a wide variety of cells in the body, playing crucial roles in many physiological responses and are involved in the pathophysiology of cardiovascular diseases (CVDs). Recently, there is great progress in discoveries that some novel cytokines, including secreted frizzled-related proteins (SFRPs), adiponectin, and C1q/TNF-Related Proteins (CTRPs), can perform a protective effect in cardiometabolic diseases, heart failure and coronary heart disease. However, the mechanisms underlying the molecular and pathophysiological actions of these cytokines in CVDs are still vague. Novel mechanisms of cell death including pyroptosis, autophagy, ferroptosis, cuproptosis, and PANoptosis have been considered novel therapeutic targets for CVDs. Some cytokines have been shown to regulate the cell death pathway in the incidence and development of CVDs. Further investigations are needed to understand the link between these novel cytokines and novel cell death models and pathways in CVDs.

Women in Cardiovascular Genetics and Systems Medicine

Women in Cardiovascular Genetics and Systems Medicine
Author: Laura Arbour
Publisher: Frontiers Media SA
Total Pages: 153
Release: 2024-04-16
Genre: Medical
ISBN: 2832547966
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At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and STEM research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.​

Calcific Aortic Valve Disease

Calcific Aortic Valve Disease
Author: Elena Aikawa
Publisher: BoD – Books on Demand
Total Pages: 544
Release: 2013-06-12
Genre: Medical
ISBN: 9535111507
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Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

Side Effects of Drugs Annual

Side Effects of Drugs Annual
Author:
Publisher: Elsevier
Total Pages: 618
Release: 2023-10-30
Genre: Medical
ISBN: 0443193975
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Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 45, first published in 1977, presents clinicians and medical investigators with a critical survey of new data and trends in adverse drug reactions and interactions. Topics covered include ADRs, ADEs and SEDs: A Bird's Eye View, Lithium, Drugs of abuse, Side effects of drugs used in the treatment of Alzheimer's disease, Sedatives and hypnotics, Antipsychotic agents, Anti-epileptic Medications, Side effects of opioid analgesics and narcotic antagonists, Anti-inflammatory and antipyretic analgesics and drugs used in gout, Side effects of local anesthetics and therapeutic gases, and more. Other sections covered include Antihistamines (H1 receptor antagonists), Drugs that act on the respiratory tract, Positive inotropic drugs and drugs used in dysrhythmias, Beta adrenergic antagonists and antianginal drugs, Drugs acting on the cerebral and peripheral circulations, Antihypertensive drugs, and much much more. - Provides a critical yearly survey of the new data and trends regarding the side effects of drugs - Authored and reviewed by worldwide pioneers in the clinical and practice sciences - Presents an essential clinical guide on the side effects of drugs for practitioners and healthcare professionals alike