Cardiac Mechanics Physiological Clinical And Mathematical Considerations
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| Author | : Liang Zhong |
| Publisher | : World Scientific |
| Total Pages | : 458 |
| Release | : 2019-04-26 |
| Genre | : Medical |
| ISBN | : 9813270659 |
Cardiovascular diseases (CVD) including heart diseases, peripheral vascular disease and heart failure, account for one-third of deaths throughout the world. CVD risk factors include systolic blood pressure, total cholesterol, high-density lipoprotein cholesterol, and diabetic status. Clinical trials have demonstrated that when modifiable risk factors are treated and corrected, the chances of CVD occurring can be reduced. This illustrates the importance of this book's elaborate coverage of cardiovascular physiology by the application of mathematical and computational methods.This book has literally transformed Cardiovascular Physiology into a STEM discipline, involving (i) quantitative formulations of heart anatomy and physiology, (ii) technologies for imaging the heart and blood vessels, (iii) coronary stenosis hemodynamics measure by means of fractional flow reserve and intervention by grafting and stenting, (iv) fluid mechanics and computational analysis of blood flow in the heart, aorta and coronary arteries, and (v) design of heart valves, percutaneous valve stents, and ventricular assist devices.So how is this mathematically and computationally configured landscape going to impact cardiology and even cardiac surgery? We are now entering a new era of mathematical formulations of anatomy and physiology, leading to technological formulations of medical and surgical procedures towards more precise medicine and surgery. This will entail reformatting of (i) the medical MD curriculum and courses, so as to educate and train a new generation of physicians who are conversant with medical technologies for applying into clinical care, as well as (ii) structuring of MD-PhD (Computational Medicine and Surgery) Program, to train competent medical and surgical specialists in precision medical care and patient-specific surgical care.This book provides a gateway for this new emerging scenario of (i) science and engineering based medical educational curriculum, and (ii) technologically oriented medical and surgical procedures. As such, this book can be usefully employed as a textbook for courses in (i) cardiovascular physiology in both the schools of engineering and medicine of universities, as well as (ii) cardiovascular engineering in biomedical engineering departments worldwide.
| Author | : Joel A. Kaplan |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 1691 |
| Release | : 2016-10-20 |
| Genre | : Medical |
| ISBN | : 0323463010 |
Now in a revised and expanded 7th Edition, Kaplan's Cardiac Anesthesia helps you optimize perioperative outcomes for patients undergoing both cardiac and noncardiac surgery. Dr. Joel L. Kaplan, along with associate editors, Drs. John G. T. Augoustides, David L. Reich, and Gerard R. Manecke, guide you through today's clinical challenges, including the newest approaches to perioperative assessment and management, state-of-the art diagnostic techniques, and cardiovascular and coronary physiology. - Complete coverage of echocardiography and current monitoring techniques. - Guidance from today's leaders in cardiac anesthesia, helping you avoid complications and ensure maximum patient safety. - More than 800 full-color illustrations. - A new section on anesthetic management of the cardiac patient undergoing noncardiac surgery. - New availability as an eBook download for use the in OR. - Online-only features, including quarterly updates, an ECG atlas...an increased number of videos, including 2-D and 3-D TEE techniques in real time...and an Annual Year End Highlight from the Journal of Cardiovascular Anesthesia that's posted each February. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices.
| Author | : William R. Milnor |
| Publisher | : |
| Total Pages | : 526 |
| Release | : 1990 |
| Genre | : Medical |
| ISBN | : 9780195058840 |
This book provides coverage of the mammalian cardiovascular system and the physiological mechanisms that maintain normal function, from the molecular and cellular level to the integrated function of the entire human organism. The author also reviews historical developments in the field, and offers a detailed survey of hemodynamic variables and methods for measuring cardiovascular function.
| Author | : Herbert Jerome Levine |
| Publisher | : |
| Total Pages | : 982 |
| Release | : 1976 |
| Genre | : Medical |
| ISBN | : |
| Author | : Robert M. Miura |
| Publisher | : American Mathematical Soc. |
| Total Pages | : 250 |
| Release | : 1986-12-31 |
| Genre | : Science |
| ISBN | : 9780821897102 |
Currently the outstanding problem in muscle contraction is determining the mechanism for the sliding of actin and myosin filaments. This volume contains papers based on lectures presented at the Seventeenth Annual Symposium on Some Mathematical Questions in Biology which was held in conjunction with the Annual Meeting of the AAAS. The six papers deal with overlapping areas of muscle physiology: cross-bridge dynamics (the mechanism currently receiving most attention), as well as distinctions between striated and cardiac muscles and the control of muscular contractions by action potentials. Focusing on both experimental techniques and theoretical underpinnings, the authors present the recent technological advances that provide an improved database for obtaining a better understanding of the biochemical mechanics and developing better mathematical models. In the first article Dr. Hugh E. Huxley reviews current studies of muscle systems which use X-ray diffraction and electron-microscopic analysis. Dr. Even Eisenberg describes how ATP hydrolysis drives muscle contraction via the action of myosin cross-bridges. The next two papers contain mathematical studies of muscle contraction. Dr. Michael Propp uses a thermodynamic formalism to predict the physiological properties of muscle. Drs. H. Michael Lacker and Charles S. Peskin develop a mathematical method for working backwards to determine uniquely microscopic properties of the cross-bridges. Drs. John W. Krueger and Katsuhiko Tsujioka use light diffraction observations to develop a quantitative understanding of cardiac function from properties of the myofibril and elements of the cross-bridge cycle. In the concluding paper, Dr. Robert S. Eisenberg reviews the current work on the electrical control mechanisms in excitation-contraction coupling which lead to muscle contraction.
| Author | : National Library of Medicine (U.S.) |
| Publisher | : |
| Total Pages | : 1242 |
| Release | : 1974 |
| Genre | : Medicine |
| ISBN | : |
First multi-year cumulation covers six years: 1965-70.
| Author | : J. Baan |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 539 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 940098796X |
Cardiac Dynamics is the name of a relatively young field of study, born from the fruitful interaction between branches of two different disciplines: medicine and physics. "Dynamics" is the branch of physics which deals with the action of forces on bodies or particles in motion or at rest. "Cardiac" relates to the clinical field of cardiology but also to cardiophysiology, both of which are specialized branches of medicine. Narrower than the well established field of Hemodynamics, Cardiac Dynamics is restricted to dynamic phenomena occurring in and around the heart. The mathematical treatment of such phenomena, however, is vastly more complex because of the intricate nature of the mechanisms involved in the cardiac action. Thus, whereas hemodynamics is concerned with predominantly passive (visco-) elastic structures - vessels - containing time-variant flow of viscous flui- blood -, the mechanical study of the heart requires additional con siderations such as: active elastic components representing the contractile mechanism of cardiac muscle, complex geometry and fiber structure in the myocardial wall, autoregulatory mechanisms, and intricate flow patterns associated with valve motion. Viewed in this light it is not surprising that attempts to describe ventricular pump function and to quantify contractile performance have not reached the level of sophistication which is common in e. g. arterial hemodynamics. For the same reason, many of the often simplified approaches to describe ventricular mechanics failed to stand up to more rigorous theoretical, experimental or clinical testing.
| Author | : Uri Dinnar |
| Publisher | : CRC Press |
| Total Pages | : 261 |
| Release | : 2019-08-15 |
| Genre | : Medical |
| ISBN | : 1000693805 |
First Published in 1981, this book offers a full, comprehensive guide to the operation of cardiovascular fluid systems. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for cardiologists, haematologists, students of medicine, and other practitioners in their respective fields.
| Author | : S. Sideman |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 448 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 9400949928 |
The ultrasound velocity tomography allows measurement of cardiac geometries for various phases in the cardiac cycle. The present tomograph makes reconstruc tions at intervals of 20 ms. Because of a lack of clear (intramural) landmarks (except the roots of the papillairy muscle), it is difficult to pinpoint spatial trajectories of particular points in the heart. Therefore, a second method was developed of injecting radiopaque markers in the heart and following their motion patterns during the cardiac cycle with help of a biplane X-ray equipment. The data obtained with both methods can be implemented in our finite element model of the heart to compute intramural stresses and strains. The results obtained sofar with the extended Darcy equation to account for the interaction of blood rheology and tissue mechanics look promising. Further testing with more sophisticated subjects than mentioned in Figure 9 is required before it will be implemented in our finite element model of the heart. We conclude that analysis of regional cardiac function, including regional myocardial blood flow, requires still a major research effort but the results obtained sofar justify, to our opinion, a continuation in this direction. Acknowledgement The authors acknowledge Dr. C. Borst and coworkers for doing the animal experiments and prof. Van Campen and dr. Grootenboer for their participation is some aspects of this work.
| Author | : J. Mazumdar |
| Publisher | : Cambridge University Press |
| Total Pages | : 244 |
| Release | : 1999-08-19 |
| Genre | : Mathematics |
| ISBN | : 9780521646758 |
This textbook is concerned with the mathematical modelling of biological and physiological phenomena for mathematically sophisticated students. A range of topics are discussed: diffusion population dynamics, autonomous differential equations and the stability of ecosystems, biogeography, pharmokinetics, biofluid mechanics, cardiac mechanics, the spectral analysis of heart sounds using FFT techniques. The last chapter deals with a wide variety of commonly used medical devices. This book is based on courses taught by the author over many years and the material is well class tested. The reader is aided by many exercises that examine key points and extend the presentation in the body of the text. All students of mathematical biology will find this book to be a highly useful resource.
