Can Risk Assessment Be Improved With Time To Event Models
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Author | : Mark Crane |
Publisher | : CRC Press |
Total Pages | : 193 |
Release | : 2016-04-19 |
Genre | : Mathematics |
ISBN | : 1420032283 |
How can environmental regulators use information on 48-hour toxicity tests to predict the effects of a few minutes of pollution? Or, at the other extreme, what is the relevance of 96-hour toxicity data for organisms that may have been exposed to a pollutant for six months or more? Time to event methods are the key to answering these types of questi
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 668 |
Release | : 1994-01-01 |
Genre | : Science |
ISBN | : 030904894X |
The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.
Author | : Richard D. Riley |
Publisher | : Oxford University Press |
Total Pages | : 373 |
Release | : 2019-01-17 |
Genre | : Medical |
ISBN | : 0192516655 |
"What is going to happen to me?" Most patients ask this question during a clinical encounter with a health professional. As well as learning what problem they have (diagnosis) and what needs to be done about it (treatment), patients want to know about their future health and wellbeing (prognosis). Prognosis research can provide answers to this question and satisfy the need for individuals to understand the possible outcomes of their condition, with and without treatment. Central to modern medical practise, the topic of prognosis is the basis of decision making in healthcare and policy development. It translates basic and clinical science into practical care for patients and populations. Prognosis Research in Healthcare: Concepts, Methods and Impact provides a comprehensive overview of the field of prognosis and prognosis research and gives a global perspective on how prognosis research and prognostic information can improve the outcomes of healthcare. It details how to design, carry out, analyse and report prognosis studies, and how prognostic information can be the basis for tailored, personalised healthcare. In particular, the book discusses how information about the characteristics of people, their health, and environment can be used to predict an individual's future health. Prognosis Research in Healthcare: Concepts, Methods and Impact, addresses all types of prognosis research and provides a practical step-by-step guide to undertaking and interpreting prognosis research studies, ideal for medical students, health researchers, healthcare professionals and methodologists, as well as for guideline and policy makers in healthcare wishing to learn more about the field of prognosis.
Author | : Louis Anthony Cox Jr. |
Publisher | : Springer Science & Business Media |
Total Pages | : 403 |
Release | : 2013-02-03 |
Genre | : Business & Economics |
ISBN | : 1461460581 |
Improving Risk Analysis shows how to better assess and manage uncertain risks when the consequences of alternative actions are in doubt. The constructive methods of causal analysis and risk modeling presented in this monograph will enable to better understand uncertain risks and decide how to manage them. The book is divided into three parts. Parts 1 shows how high-quality risk analysis can improve the clarity and effectiveness of individual, community, and enterprise decisions when the consequences of different choices are uncertain. Part 2 discusses social decisions. Part 3 illustrates these methods and models, showing how to apply them to health effects of particulate air pollution. "Tony Cox’s new book addresses what risk analysts and policy makers most need to know: How to find out what causes what, and how to quantify the practical differences that changes in risk management practices would make. The constructive methods in Improving Risk Analysis will be invaluable in helping practitioners to deliver more useful insights to inform high-stakes decisions and policy,in areas ranging from disaster planning to counter-terrorism investments to enterprise risk management to air pollution abatement policies. Better risk management is possible and practicable; Improving Risk Analysis explains how." Elisabeth Pate-Cornell, Stanford University "Improving Risk Analysis offers crucial advice for moving policy-relevant risk analyses towards more defensible, causally-based methods. Tony Cox draws on his extensive experience to offer sound advice and insights that will be invaluable to both policy makers and analysts in strengthening the foundations for important risk analyses. This much-needed book should be required reading for policy makers and policy analysts confronting uncertain risks and seeking more trustworthy risk analyses." Seth Guikema, Johns Hopkins University "Tony Cox has been a trail blazer in quantitative risk analysis, and his new book gives readers the knowledge and tools needed to cut through the complexity and advocacy inherent in risk analysis. Cox’s careful exposition is detailed and thorough, yet accessible to non-technical readers interested in understanding uncertain risks and the outcomes associated with different mitigation actions. Improving Risk Analysis should be required reading for public officials responsible for making policy decisions about how best to protect public health and safety in an uncertain world." Susan E. Dudley, George Washington University
Author | : Gary L. Richardson |
Publisher | : CRC Press |
Total Pages | : 116 |
Release | : 2021-12-15 |
Genre | : Business & Economics |
ISBN | : 1000533468 |
This book is designed to be a quick guidelines-oriented approach to the topic of project management. It contains the essential management practices required to produce successful project outcomes. Guidelines for Achieving Project Management Success helps the non-technical reader who might have been originally put off by a more robust treatment of project management. It uses the 80/20 rule where 80% of the project management problem may originate from just 20% of the cause. The book includes easy to understand examples illustrating key topics and offers advice and references for further reading. The book also helps the reader on how to define what the target is with the project and how to execute it to get the desired results. The primary audience is individuals who are seeking a readable description of the project management processes. The book is also useful for an academic program where project management is secondary to the primary topic.
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 180 |
Release | : 2003-06-13 |
Genre | : Science |
ISBN | : 0309167949 |
The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards. Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 161 |
Release | : 2010-09-10 |
Genre | : Political Science |
ISBN | : 0309161525 |
The events of September 11, 2001 changed perceptions, rearranged national priorities, and produced significant new government entities, including the U.S. Department of Homeland Security (DHS) created in 2003. While the principal mission of DHS is to lead efforts to secure the nation against those forces that wish to do harm, the department also has responsibilities in regard to preparation for and response to other hazards and disasters, such as floods, earthquakes, and other "natural" disasters. Whether in the context of preparedness, response or recovery from terrorism, illegal entry to the country, or natural disasters, DHS is committed to processes and methods that feature risk assessment as a critical component for making better-informed decisions. Review of the Department of Homeland Security's Approach to Risk Analysis explores how DHS is building its capabilities in risk analysis to inform decision making. The department uses risk analysis to inform decisions ranging from high-level policy choices to fine-scale protocols that guide the minute-by-minute actions of DHS employees. Although DHS is responsible for mitigating a range of threats, natural disasters, and pandemics, its risk analysis efforts are weighted heavily toward terrorism. In addition to assessing the capability of DHS risk analysis methods to support decision-making, the book evaluates the quality of the current approach to estimating risk and discusses how to improve current risk analysis procedures. Review of the Department of Homeland Security's Approach to Risk Analysis recommends that DHS continue to build its integrated risk management framework. It also suggests that the department improve the way models are developed and used and follow time-tested scientific practices, among other recommendations.
Author | : dall'Acqua, Luisa |
Publisher | : IGI Global |
Total Pages | : 341 |
Release | : 2018-02-09 |
Genre | : Business & Economics |
ISBN | : 1522539077 |
The success of any corporate enterprise is reliant upon the effectiveness of its leadership. The methods used to prepare corporate leaders can have a significant impact on the success of the employees and the company. Improving Business Performance Through Effective Managerial Training Initiatives is a critical scholarly publication that explores leadership within corporations and how proper education can lead to positive outcomes within corporations. Featuring coverage on a wide range of topics, including managerial mindsets, learning-performance relationship, and strategic risk management, this book is geared toward academicians, researchers, students, and policy makers seeking relevant research on the importance of quality leadership education within corporations to promote success.
Author | : Douglas McNair |
Publisher | : |
Total Pages | : 138 |
Release | : 2019-11-06 |
Genre | : |
ISBN | : 1839623225 |
Author | : National Research Council |
Publisher | : National Academies Press |
Total Pages | : 172 |
Release | : 2009-01-03 |
Genre | : Political Science |
ISBN | : 0309120284 |
The mission of Department of Homeland Security Bioterrorism Risk Assessment: A Call for Change, the book published in December 2008, is to independently and scientifically review the methodology that led to the 2006 Department of Homeland Security report, Bioterrorism Risk Assessment (BTRA) and provide a foundation for future updates. This book identifies a number of fundamental concerns with the BTRA of 2006, ranging from mathematical and statistical mistakes that have corrupted results, to unnecessarily complicated probability models and models with fidelity far exceeding existing data, to more basic questions about how terrorist behavior should be modeled. Rather than merely criticizing what was done in the BTRA of 2006, this new NRC book consults outside experts and collects a number of proposed alternatives that could improve DHS's ability to assess potential terrorist behavior as a key element of risk-informed decision making, and it explains these alternatives in the specific context of the BTRA and the bioterrorism threat.