Eastern boundary upwelling systems (EBUS) have historically received attention from the scientific community due to their impact on the economic development of these highly productive systems. Remote sensing, numerical modeling, and in situ observations have increased their spatial and temporal resolutions during the last 40 years in their strategy to provide reliable products about the actual state of the ocean. The assembly of several data sources currently constitutes an opportunity to increase our knowledge about the present and future state of the relatively narrow and highly variable EBUS. The primary forcing mechanism in the upwelling regions is the wind stress in areas close to the coast. Long-term trends in wind intensity in upwelling areas present considerable uncertainties as the different wind databases produce divergent results. On the other hand, although the effect of climate change in the interior ocean is increasing temperatures in upwelling areas, the long-term trends seem to be in the opposite direction. Hence, assessing the long-term impact of the environmental conditions on upwelling development represents a major challenge for the scientific community. This special issue aims to discuss the state-of-the-art understanding of dynamical processes governing the ocean at the eastern boundary upwelling systems in a changing ocean.