Cadmium Toxicity

Cadmium Toxicity
Author: Seiichiro Himeno
Publisher: Springer
Total Pages: 190
Release: 2019-02-09
Genre: Medical
ISBN: 981133630X

This volume focuses on cadmium (Cd) exposure, its effects on human health, the mechanism of Cd accumulation and the development of mitigation technologies. Further, it discusses clinical, epidemiological, agricultural, toxicological, and biochemical aspects of Cd pollution and presents recent biochemical studies on molecular mechanisms of Cd cytotoxicity and cellular transport as well as the mechanism of Cd-induced disturbances in phosphorus (P) metabolism. It also provides insights into the pathophysiology of itai-itai disease, a serious condition caused by Cd pollution. Cadmium -New Aspects in Human Disease, Rice Contamination, and Cytotoxicity- is a valuable resource for scientists involved in heavy metal toxicology, botanical sciences, and regulatory sciences. Addressing the features of Cd pollution in the past and in the present, as well as future perspectives, this is a must-have book for students, researchers and practitioners interested in global and local metal pollution.

Toxicologic Assessment of the Army's Zinc Cadmium Sulfide Dispersion Tests

Toxicologic Assessment of the Army's Zinc Cadmium Sulfide Dispersion Tests
Author: National Research Council
Publisher: National Academies Press
Total Pages: 386
Release: 1997-05-30
Genre: Nature
ISBN: 0309174783

During the 1950s and 1960s, the U.S. Army conducted atmospheric dispersion tests in many American cities using fluorescent particles of zinc cadmium sulfide (ZnCdS) to develop and verify meteorological models to estimate the dispersal of aerosols. Upon learning of the tests, many citizens and some public health officials in the affected cities raised concerns about the health consequences of the tests. This book assesses the public health effects of the Army's tests, including the toxicity of ZnCdS, the toxicity of surrogate cadmium compounds, the environmental fate of ZnCdS, the extent of public exposures from the dispersion tests, and the risks of such exposures.

Chelation Therapy in the Treatment of Metal Intoxication

Chelation Therapy in the Treatment of Metal Intoxication
Author: Jan Aaseth
Publisher: Academic Press
Total Pages: 390
Release: 2016-04-18
Genre: Medical
ISBN: 0128030739

Chelation Therapy in the Treatment of Metal Intoxication presents a practical guide to the use of chelation therapy, from its basic chemistry, to available chelating antidotes, and the application of chelating agents. Several metals have long been known to be toxic to humans, and continue to pose great difficulty to treat. These challenges pose particular problems in industrial settings, with lead smelting known to be associated with hemopoietic alterations and paralyses, and the inhalation of mercury vapor in mercury mining being extremely detrimental to the central nervous system. Clinical experience has demonstrated that acute and chronic human intoxications with a range of metals can be treated efficiently by administration of chelating agents. Chelation Therapy in the Treatment of Metal Intoxication describes the chemical and biological principles of chelation in the treatment of these toxic metal compounds, including new chelators such as meso-2,3-dimercaptosuccinic acid (DMSA) and D,L-2,3-dimercapto-1-propanesulfonic acid (DMPS). - Presents all the current findings on the potential for chelation as a therapy for metal intoxication - Presents practical guidelines for selecting the most appropriate chelating agent - Includes coverage on radionuclide exposure and metal storage diseases - Describes the chemical and biological principles of chelation in the treatment of toxic metal compounds

Cadmium

Cadmium
Author: Mirza Hasanuzzaman
Publisher: Nova Science Publishers
Total Pages: 0
Release: 2013
Genre: Cadmium
ISBN: 9781628087222

Cadmium (Cd) is one of the four metals that have been raising apprehension world-wide as environmental, agricultural and health hazards in recent decades. Cadmium accumulates in the soil naturally or through anthropogenic activities, such as mining, industrial waste disposal, use and disposal of batteries and sludges, and application of pesticides and fertilisers. Cadmium accumulation can result in severe deterioration of natural resources, disturbance of ecosystems, and deleterious effects on plants, animals and human health. In recent decades, the number of publications focused on cadmium toxicity in plants and animals has been growing exponentially, making this topic impossible to accommodate within the scope of a single volume. This book edited by Dr Mirza Hasanuzzaman and Dr Masayuki Fujita presents a collection of 16 chapters written by 67 experts from 19 countries working on cadmium toxicity. This volume provides the readers with a background for understanding cadmium toxicity, its environmental and health aspects, and its remediation mechanisms. Various chapters included in this book provide a state-of-the-art account of the information as a resourceful guide suited for scholars and researchers working in the field of cadmium. This book is a invaluable resource for plant biologists, agriculturists, toxicologists, biochemists, environmental scientists, physiologists, pharmacologists, geneticists, molecular biologists; as well as graduate students in these disciplines.

Cadmium in the Environment

Cadmium in the Environment
Author: Lars Friberg
Publisher: CRC Press
Total Pages: 233
Release: 2018-01-18
Genre: Science
ISBN: 1351087274

The focus of this report is upon information essential to the understanding of the toxic action of cadmium and the relationship between dose (exposure) and effects on human beings and animals. The therapy of cadmium poisoning has not been discussed.This review on cadmium in the environment has been performed under a contract between the U.S. Environmental Protection Agency and the Department of Environmental Hygiene of the Karolinska Institute, Sweden. The report is intended to serve as a background paper for a future Air Quality Criteria document on cadmium. Therefore, particular attention has been given to information relevant for the evaluation of risks due to long-term exposure to low concentrations of cadmium. Acute effects from short-term exposure to high concentrations are dealt with briefly. In vitro studies without bearing on the main problem have not been dealt with.The report is not limited to effects from exposure via inhalation. Newly accessible information, showing that large populations may be exposed considerably via the oral route, can elucidate chronic effects of cadmium in general. Man and animals can be victims of secondary exposure through vehicles such as food and water which have been contaminated by cadmium in air.

Environmental Medicine

Environmental Medicine
Author: Committee on Curriculum Development in Environmental Medicine
Publisher: National Academies Press
Total Pages: 988
Release: 1995-05-12
Genre: Medical
ISBN: 0309568722

People are increasingly concerned about potential environmental health hazards and often ask their physicians questions such as: "Is the tap water safe to drink?" "Is it safe to live near power lines?" Unfortunately, physicians often lack the information and training related to environmental health risks needed to answer such questions. This book discusses six competency based learning objectives for all medical school students, discusses the relevance of environmental health to specific courses and clerkships, and demonstrates how to integrate environmental health into the curriculum through published case studies, some of which are included in one of the book's three appendices. Also included is a guide on where to obtain additional information for treatment, referral, and follow-up for diseases with possible environmental and/or occupational origins.

Cadmium and Health

Cadmium and Health
Author: Lars T. Friberg
Publisher: CRC Press
Total Pages: 342
Release: 2019-06-27
Genre: Medical
ISBN: 0429536208

Published in 1986: Volume 2: Effects and Response, is primarily devoted to the toxicology of cadmium and includes effects on the respiratory system, kidneys, and bone as well as other toxic effects, including those from the hemaopoietic and cardiovascular system, the liver, the reproductive organs, and the fetus.

Cadmium: From Toxicity to Essentiality

Cadmium: From Toxicity to Essentiality
Author: Astrid Sigel
Publisher: Springer Science & Business Media
Total Pages: 590
Release: 2013-02-26
Genre: Science
ISBN: 9400751796

Volume 11 provides in an authoritative and timely manner in 16 stimulating chapters, written by 40 internationally recognized experts from 11 nations, and supported by more than 2600 references, 35 tables, and over 100 illustrations, many in color, a most up-to-date view on the role of cadmium for life, presently a vibrant research area. MILS-11 covers the bioinorganic chemistry of Cd(II), its biogeochemistry, anthropogenic release into the environment, and speciation in the atmosphere, waters, soils, and sediments. The analytical tools for Cd determination, its imaging in cells, and the use of 113Cd NMR to probe Zn(II) and Ca(II) proteins are summarized, as are Cd(II) interactions with nucleotides, nucleic acids, amino acids, and proteins including metallothioneins. The phytoremediation by Cd(II)-accumulating plants, etc., the toxicology of Cd(II), its damage to mammalian organs, and its role as a carcinogen for humans, are highlighted.