Drosophila

Drosophila
Author: Christian Dahmann
Publisher: Springer Nature
Total Pages: 423
Release: 2022-08-18
Genre: Science
ISBN: 1071625411

This third edition expands on the previous editions by providing updated protocols and current methods that cover recent breakthroughs in Drosophila research. Chapters guide readers through FlyBase, versatile gene expression systems, analysis of microRNA function, single-cell transcriptome data and metabolism, recent applications of CRISPR for precise genome editing, transcriptional activation and cell lineage tracing, protein inhibition and tagging, optogenetic and optochemical control of tissue mechanics, AFM measurements, sample preparation for electron microscopy, live imaging of different tissues and organs, and quantitative image analysis. Written in the format of the highly successful Methods in Molecular Biology series, chapters include an introduction to their topic, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls Authoritative and cutting-edge, Drosophila: Methods and Protocols, Third Edition serves as a useful and practical guide to new researchers and experts using Drosophila as a model system. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Medical Image Computing and Computer Assisted Intervention – MICCAI 2020

Medical Image Computing and Computer Assisted Intervention – MICCAI 2020
Author: Anne L. Martel
Publisher: Springer Nature
Total Pages: 819
Release: 2020-10-02
Genre: Computers
ISBN: 3030597253

The seven-volume set LNCS 12261, 12262, 12263, 12264, 12265, 12266, and 12267 constitutes the refereed proceedings of the 23rd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2020, held in Lima, Peru, in October 2020. The conference was held virtually due to the COVID-19 pandemic. The 542 revised full papers presented were carefully reviewed and selected from 1809 submissions in a double-blind review process. The papers are organized in the following topical sections: Part I: machine learning methodologies Part II: image reconstruction; prediction and diagnosis; cross-domain methods and reconstruction; domain adaptation; machine learning applications; generative adversarial networks Part III: CAI applications; image registration; instrumentation and surgical phase detection; navigation and visualization; ultrasound imaging; video image analysis Part IV: segmentation; shape models and landmark detection Part V: biological, optical, microscopic imaging; cell segmentation and stain normalization; histopathology image analysis; opthalmology Part VI: angiography and vessel analysis; breast imaging; colonoscopy; dermatology; fetal imaging; heart and lung imaging; musculoskeletal imaging Part VI: brain development and atlases; DWI and tractography; functional brain networks; neuroimaging; positron emission tomography

Neurovirology: Viruses and the Brain

Neurovirology: Viruses and the Brain
Author:
Publisher: Elsevier
Total Pages: 661
Release: 2001-07-06
Genre: Medical
ISBN: 0080493807

This volume is the first in a planned series of thematic volumes for Advances in Virus Research. It covers the etiology, pathogenetic mechanisms, and clincial consequences of human neurotropic viruses. Buchmeier is a virologist, Campbell an immunologist, and both are extremely well known in their fields. Numerous illustrations including colour Knowledgeable discussion of the potential role of viral infections in teratogenic and developmental disorders Frank discussion of the role of stress in disease Behavioural consequences of chronic CNS infection

Mind Chi

Mind Chi
Author: Vanda North
Publisher: John Wiley & Sons
Total Pages: 360
Release: 2010-01-05
Genre: Business & Economics
ISBN: 1907321373

8 minutes a day is all it takes to open up a world of superiormental performance. Just as Tai Chi has been used for centuries to balance body andmind, Mind Chi will help you increase your mentalenergy and be more effective in everything you do. And all you needis 8 minutes a day... Mind Chi is a powerful synthesis of thought andaction based on the most recent research into how the brain works.By following the simple, daily exercises in this book, you willraise your mental performance to a level you never thoughtpossible. Discover: Sharper powers of concentration and information management Improved control over your attention span, memory, thoughts andfeelings Fast and easy ways to reduce your stress and increase yourconfidence New positive habits, thoughts and mental resilience Fantastic energy levels, during and after your work day Plus: 50 Strategies for Success in Business &Life "An eight minute daily dose of Mind Chi willimprove vitality, reduce stress and allow us to see the manyblessings of life more clearly." --Stephen C. Lundin PhD, author ofthe five million copy bestselling FISH!

Patient-Specific Stem Cells

Patient-Specific Stem Cells
Author: Deepak A. Lamba
Publisher: CRC Press
Total Pages: 279
Release: 2017-04-07
Genre: Medical
ISBN: 1315402173

One of the biggest challenges faced in medical research had been to create accurate and relevant models of human disease. A number of good animal models have been developed to understand the pathophysiology. However, not all of them reflect the human disorder, a classic case being Usher’s syndrome where the mutant mice do not have the same visual and auditory defects that patients face. There are others which have been even more difficult to model due to the multi-factorial nature of the condition and due to lack of discovery of a single causative gene such as age-related macular degeneration or Alzheimer’s syndrome. Thus a more relevant and accurate system will allow us to make better predictions on relevant therapeutic approaches. The discovery of human pluripotent stem cells in 1998 followed by the technological advances to reprogram somatic cells to pluripotent-stem cell-like cells in 2006 has completely revolutionized the way we can now think about modelling human development and disease. This now coupled with genome editing technologies such as TALENS and CRISPRs have now set us up to develop in vitro models both 2D as well as 3D organoids, which can more precisely reflect the disease in the patients. These combinatorial technologies are already providing us with better tools and therapeutics in drug discovery or gene therapy. This book summarizes both the technological advances in the field of generation of patient specific lines as well as various gene editing approaches followed by its applicability in various systems. The book will serve as a reference for the current state of the field as it: -Provides a comprehensive overview of the status of the field of patients derived induced pluripotent stem cells. -Describes the use of cardiac cells as a main featured component within the book. -Examines drug toxicity analysis as a working example throughout the book.

Kaplan and Sadock's Comprehensive Text of Psychiatry

Kaplan and Sadock's Comprehensive Text of Psychiatry
Author: Robert Boland
Publisher: Lippincott Williams & Wilkins
Total Pages: 13606
Release: 2024-03-26
Genre: Medical
ISBN: 1975175743

The gold standard reference for all those who work with people with mental illness, Kaplan & Sadock's Comprehensive Textbook of Psychiatry, edited by Drs. Robert Boland and Marcia L. Verduin, has consistently kept pace with the rapid growth of research and knowledge in neural science, as well as biological and psychological science. This two-volume eleventh edition offers the expertise of more than 600 renowned contributors who cover the full range of psychiatry and mental health, including neural science, genetics, neuropsychiatry, psychopharmacology, and other key areas.

The Gamer's Brain

The Gamer's Brain
Author: Celia Hodent
Publisher: CRC Press
Total Pages: 267
Release: 2017-08-10
Genre: Computers
ISBN: 1498775527

Making a successful video game is hard. Even games that are well-received at launch may fail to engage players in the long term due to issues with the user experience (UX) that they are delivering. That’s why makers of successful video games like Fortnite and Assassin’s Creed invest both time and money perfecting their UX strategy. These top video game creators know that a bad user experience can ruin the prospects for any game, regardless of its budget, scope, or ambition. The game UX accounts for the whole experience players have with a video game, from first hearing about it to navigating menus and progressing in the game. UX as a discipline offers guidelines to assist developers in creating the optimal experience they want to deliver, including shipping higher quality games (whether indie, triple-A or "serious" games) and meeting business goals -- all while staying true to design vision and artistic intent. At its core, UX is about understanding the gamer’s brain: understanding human capabilities and limitations to anticipate how a game will be perceived, the emotions it will elicit, how players will interact with it, and how engaging the experience will be. This book is designed to equip readers of all levels, from student to professional, with cognitive science knowledge and user experience guidelines and methodologies. These insights will help readers identify the ingredients for successful and engaging video games, empowering them to develop their own unique game recipe more efficiently, while providing a better experience for their audience. "The Gamer's Brain: How Neuroscience and UX Can Impact Video Game Design" Is written by Celia Hodent -- a UX expert with a PhD in psychology who has been working in the entertainment industry for over 10 years, including at prominent companies such as Epic Games (Fortnite), Ubisoft, and LucasArts. Major themes explored in this book: Provides an overview of how the brain learns and processes information by distilling research findings from cognitive science and psychology research in a very accessible way. Topics covered include: "neuromyths", perception, memory, attention, motivation, emotion, and learning. Includes numerous examples from released games of how scientific knowledge translates into game design, and how to use a UX framework in game development. Describes how UX can guide developers to improve the usability and the level of engagement a game provides to its target audience by using cognitive psychology knowledge, implementing human-computer interaction principles, and applying the scientific method (user research). Provides a practical definition of UX specifically applied to games, with a unique framework. Defines the most relevant pillars for good usability (ease of use) and good "engage-ability" (the ability of the game to be fun and engaging), translated into a practical checklist. Covers design thinking, game user research, game analytics, and UX strategy at both a project and studio level. This book is a practical tool that any professional game developer or student can use right away and includes the most complete overview of UX in games existing today.

Recent Advances and the Future Generation of Neuroinformatics Infrastructure

Recent Advances and the Future Generation of Neuroinformatics Infrastructure
Author: Xi Cheng
Publisher: Frontiers Media SA
Total Pages: 390
Release: 2015-12-11
Genre: Neurosciences. Biological psychiatry. Neuropsychiatry
ISBN: 2889196771

The huge volume of multi-modal neuroimaging data across different neuroscience communities has posed a daunting challenge to traditional methods of data sharing, data archiving, data processing and data analysis. Neuroinformatics plays a crucial role in creating advanced methodologies and tools for the handling of varied and heterogeneous datasets in order to better understand the structure and function of the brain. These tools and methodologies not only enhance data collection, analysis, integration, interpretation, modeling, and dissemination of data, but also promote data sharing and collaboration. This Neuroinformatics Research Topic aims to summarize the state-of-art of the current achievements and explores the directions for the future generation of neuroinformatics infrastructure. The publications present solutions for data archiving, data processing and workflow, data mining, and system integration methodologies. Some of the systems presented are large in scale, geographically distributed, and already have a well-established user community. Some discuss opportunities and methodologies that facilitate large-scale parallel data processing tasks under a heterogeneous computational environment. We wish to stimulate on-going discussions at the level of the neuroinformatics infrastructure including the common challenges, new technologies of maximum benefit, key features of next generation infrastructure, etc. We have asked leading research groups from different research areas of neuroscience/neuroimaging to provide their thoughts on the development of a state of the art and highly-efficient neuroinformatics infrastructure. Such discussions will inspire and help guide the development of a state of the art, highly-efficient neuroinformatics infrastructure.