Brain Function and Responsiveness in Disorders of Consciousness

Brain Function and Responsiveness in Disorders of Consciousness
Author: Martin M. Monti
Publisher: Springer
Total Pages: 214
Release: 2015-11-30
Genre: Medical
ISBN: 331921425X

This book provides up-to-date information on all aspects of brain function and responsiveness in patients with severe disorders of consciousness. Topics considered include the mechanisms and measures of consciousness; perfusional, metabolic, and fMRI markers of responsiveness; responsiveness to pain; the role of brain–computer interface techniques; electrophysiology; cortical excitability; autonomic responsiveness; the natural history of vegetative and minimally conscious states; and prediction of outcome. Brain neuroimaging has documented residual responsiveness in the vegetative state. The scientific impact of this seminal evidence has generated a schism between neuroscience and the clinical criteria defining consciousness and responsiveness. Our current understanding of human consciousness must be reconsidered also in view of the emotional impact on the public and the far-reaching implications for diagnosis, prognosis, medical treatment, human costs, medical and individual responsibility, logistics, healthcare, ethics, etc. It is hoped that this book will help to bridge the gap between neuroscience and clinical routine.

Coma and Disorders of Consciousness

Coma and Disorders of Consciousness
Author: Caroline Schnakers
Publisher: Springer
Total Pages: 0
Release: 2012-06-07
Genre: Medical
ISBN: 9781447124399

In spite of medical advances and the increasing number of severely brain-injured patients, the assessment and treatment of patients recovering from coma remain challenging. For over 10 years now, the Coma Science Group has been working on the scientific exploration of disorders of consciousness, with both scientific and clinical research agendas. This book is the result of all this work. The aim is to offer both clinicians and researchers an opportunity to acquire expertise in a field which is constantly developing. Besides diagnostic, prognostic and ethical issues, this book includes well-established findings on assessment techniques (i.e., behavioral scales, electrophysiological explorations and structural/functional neuroimaging) and treatment procedures, but also techniques under development (i.e., the use of classifiers, brain-computer interfaces, transcranial magnetic stimulation or deep brain stimulation) which will stimulate ideas for future research. The Coma Science Group presents here a comprehensive book for readers, regardless of whether they are already familiar with the difficult but exciting field of disorders of consciousness.

Clinical Pathways in Stroke Rehabilitation

Clinical Pathways in Stroke Rehabilitation
Author: Thomas Platz
Publisher: Springer Nature
Total Pages: 284
Release: 2021-01-14
Genre: Medical
ISBN: 3030585050

This open access book focuses on practical clinical problems that are frequently encountered in stroke rehabilitation. Consequences of diseases, e.g. impairments and activity limitations, are addressed in rehabilitation with the overall goal to reduce disability and promote participation. Based on the available best external evidence, clinical pathways are described for stroke rehabilitation bridging the gap between clinical evidence and clinical decision-making. The clinical pathways answer the questions which rehabilitation treatment options are beneficial to overcome specific impairment constellations and activity limitations and are well acceptable to stroke survivors, as well as when and in which settings to provide rehabilitation over the course of recovery post stroke. Each chapter starts with a description of the clinical problem encountered. This is followed by a systematic, but concise review of the evidence (RCTs, systematic reviews and meta-analyses) that is relevant for clinical decision-making, and comments on assessment, therapy (training, technology, medication), and the use of technical aids as appropriate. Based on these summaries, clinical algorithms / pathways are provided and the main clinical-decision situations are portrayed. The book is invaluable for all neurorehabilitation team members, clinicians, nurses, and therapists in neurology, physical medicine and rehabilitation, and related fields. It is a World Federation for NeuroRehabilitation (WFNR) educational initiative, bridging the gap between the rapidly expanding clinical research in stroke rehabilitation and clinical practice across societies and continents. It can be used for both clinical decision-making for individuals and as well as clinical background knowledge for stroke rehabilitation service development initiatives.

The Boundaries of Consciousness: Neurobiology and Neuropathology

The Boundaries of Consciousness: Neurobiology and Neuropathology
Author: Steven Laureys
Publisher: Elsevier
Total Pages: 631
Release: 2006-08-24
Genre: Medical
ISBN: 0444528768

Consciousness is one of the most significant scientific problems today. Renewed interest in the nature of consciousness - a phenomenon long considered not to be scientifically explorable, as well as increasingly widespread availability of multimodal functional brain imaging techniques (EEG, ERP, MEG, fMRI and PET), now offer the possibility of detailed, integrated exploration of the neural, behavioral, and computational correlates of consciousness. The present volume aims to confront the latest theoretical insights in the scientific study of human consciousness with the most recent behavioral, neuroimaging, electrophysiological, pharmacological and neuropathological data on brain function in altered states of consciousness such as: brain death, coma, vegetative state, minimally conscious state, locked-in syndrome, dementia, epilepsy, schizophrenia, hysteria, general anesthesia, sleep, hypnosis, and hallucinations. The interest of this is threefold. First, patients with altered states of consciousness continue to represent a major clinical problem in terms of clinical assessment of consciousness and daily management. Second, the exploration of brain function in altered states of consciousness represents a unique lesional approach to the scientific study of consciousness and adds to the worldwide effort to identify the "neural correlate of consciousness". Third, new scientific insights in this field have major ethical and social implications regarding our care for these patients.

Brain Death and Disorders of Consciousness

Brain Death and Disorders of Consciousness
Author: Calixto Machado
Publisher: Springer Science & Business Media
Total Pages: 312
Release: 2004-03-31
Genre: Medical
ISBN: 9780306484827

Although some decades have passed, there are still worldwide controversies about a concept of human death on neurological grounds. There are also disagreements on the diagnostic criteria for brain death, whether clinical alone or clinical plus ancillary tests. Moreover, some scholars who were strong defenders of a brain-based standard of death are now favoring a circulatory-respiratory standard. The study of coma is extremely important because lesions of the brain are responsible for quality of life in patients or cause of death. The main goal of Brain Death and Disorders of Consciousness is to provide a suitable scientific platform to discuss all topics related to human death and coma.

Disorders of Consciousness

Disorders of Consciousness
Author: Kamil Hakan Dogan
Publisher: BoD – Books on Demand
Total Pages: 73
Release: 2020-03-04
Genre: Medical
ISBN: 1789853079

Consciousness is a state of being awake and aware of one's self and surroundings according to the American Academy of Neurology. A conscious person is aware of things through thoughts and the five senses: sight, hearing, smell, taste, and touch. In disorders of consciousness, the patient has trouble being awake, or being aware, or both. Thanks to advances in science and technology, we learn new information about diseases every day. This book includes current approaches to some important issues related to disorders of consciousness.

The Assessment and Rehabilitation of Vegetative and Minimally Conscious Patients

The Assessment and Rehabilitation of Vegetative and Minimally Conscious Patients
Author: Martin R. Coleman
Publisher: Taylor & Francis
Total Pages: 420
Release: 2005
Genre: Medical
ISBN: 9781841699929

The vegetative state - a condition in which someone is awake but unaware with no evidence of a working mind - is both emotive and challenging. This condition and that of someone who gains partial recovery of mental and neurological functions - known as the minimally conscious state - have provoked intense debate and considerable interest amongst scientists, health care professionals, ethicists, philosophers and lawyers. This unique special issue unites many experts in the field to review and discuss the many advances made in our understanding of these conditions. The strength of this special issue lies in the wide range of topics discussed - from definitions and diagnostic criteria to hotly debated topics such as whether a person in the vegetative state is truly unaware. This edition will serve as both a useful reference to those caring for people in these conditions as well as to those investigating the physiological basis of human consciousness.

Imaging Acute Neurologic Disease

Imaging Acute Neurologic Disease
Author: Massimo Filippi
Publisher: Cambridge University Press
Total Pages: 393
Release: 2014-09-11
Genre: Medical
ISBN: 1107035945

A comprehensive survey of best practice in using diagnostic imaging in acute neurologic conditions. The symptom-based approach guides the choice of the available imaging tools for efficient, accurate, and cost-effective diagnosis. Effective examination algorithms integrate neurological and imaging concepts with the practical demands and constraints of emergency care.

Finding Consciousness

Finding Consciousness
Author: Walter Sinnott-Armstrong
Publisher: Oxford University Press
Total Pages: 281
Release: 2016-01-13
Genre: Psychology
ISBN: 0190280328

Modern medicine enables us to keep many people alive after they have suffered severe brain damage and show no reliable outward signs of consciousness. Many such patients are misdiagnosed as being in a permanent vegetative state when they are actually in a minimally conscious state. This mistake has far-reaching implications for treatment and prognosis. To alleviate this problem, neuroscientists have recently developed new brain-scanning methods to detect consciousness in some of these patients and even to ask them questions, including "Do you want to stay alive?" Finding Consciousness: The Neuroscience, Ethics, and Law of Severe Brain Damage addresses many questions regarding these recent neuroscientific methods: Is what these methods detect really consciousness? Do patients feel pain? Should we decide whether or not to let them die or are they competent to decide for themselves? And which kinds of treatment should governments and hospitals make available? This edited volume provides contextual information, surveys the issues and positions, and takes controversial stands from a wide variety of prominent contributors in fields ranging from neuroscience and neurology to law and policy to philosophy and ethics. Finding Consciousness should interest not only neuroscientists, clinicians, and ethicists but anyone who might suffer brain damage, which includes us all.

Assessing Pain and Communication in Disorders of Consciousness

Assessing Pain and Communication in Disorders of Consciousness
Author: Camille Chatelle
Publisher: Psychology Press
Total Pages: 223
Release: 2015-12-14
Genre: Psychology
ISBN: 1317600622

Recent advances in medicine for resuscitation and care have led to an increased number of patients that survive severe brain damage but who are poorly responsive and non-communicative at the bedside. This has led to a striking need to better characterize, understand, and manage this population who present a real challenge for the assessment of pain and for planning treatment. This edited collection provides clinicians with a guide to recent developments in research on pain perception and assessment, and the detection of consciousness and communication in patients with disorders of consciousness (DOC). With contributions from leading global researchers, the book gives an overview of issues concerning the assessment of pain. It also covers the development of suitable tools both to improve pain management and to detect consciousness and communication in these patients, to influence their prognosis and treatment, and their quality of life. Methodological and ethical issues concerning the implication for future research are also considered. The book will be an invaluable guide for clinicians, medics and therapists working in rehabilitation and acute care, particularly in the demanding field of pain perception, pain assessment and detection of consciousness and communication in patients with DOC. It will also be useful for students and researchers in neuropsychology and medical sciences.