Replicants are bioengineered humans, once designed by the Tyrell Corporation for use Off-world. After a series of violent rebellions, their manufacture was prohibited, and Tyrell Corp went bankrupt. Niander Wallace acquired the remains of Tyrell Corp and created a new line of Replicants who obey. A Replicant underground survives, led by the former combat model Freysa and her human partner Aahna Ashina, known as Ash, formerly a Blade Runner. Twenty years ago, in 2019, Ash spared the Replicant Isobel Selwyn, a replica of industrialist Alexander Selwyn’s wife. Together with Alexander’s human daughter Cleo, Isobel escaped to the Off-world colonies. Searching for the late Alexander Selwyn’s research into Replicant physiology, Niander Wallace sent his creation Luv, the first Replicant Blade Runner, to hunt down both Cleo and Isobel, believing that Isobel holds the secret to Replicant fertility. To aid Luv in her mission, Wallace manufactured a new Replicant created from Ash’s DNA. While Cleo recovered from a serious gunshot wound, Ash and Mack, and old Replicant who saved Cleo’s life, set out to search Alexander Selwyn’s old family estate for Isobel. However, waiting for them was Luv and the Replicant Ash. A furious gun battle erupted and Mack was killed, with Ash captured. Only the timely intervention of Isobel saved her life, allowing them to escape. Together, they headed back to Freysa where Isobel and Cleo were finally reunited…