Biosensors for Security and Bioterrorism Applications

Biosensors for Security and Bioterrorism Applications
Author: Dimitrios P. Nikolelis
Publisher: Springer
Total Pages: 514
Release: 2016-03-12
Genre: Technology & Engineering
ISBN: 3319289268

This book offers comprehensive coverage of biomarker/biosensor interactions for the rapid detection of weapons of bioterrorism, as well as current research trends and future developments and applications. It will be useful to researchers in this field who are interested in new developments in the early detection of such. The authors have collected very valuable and, in some aspects indispensable experience in the area i.e. in the development and application of portable biosensors for the detection of potential hazards. Most efforts are centered on the development of immunochemical assays including flow-lateral systems and engineered antibodies and their fragments. In addition, new approaches to the detection of enzyme inhibitors, direct enzymatic and microbial detection of metabolites and nutrients are elaborated. Some realized prototypes and concept devices applicable for the further use as a basis for the cooperation programs are also discussed.There is a particular focus on electrochemical and optical detection systems,including those employing carbon nanotubes, quantum dots and metalnanoparticles. The authors are well-known scientists and most of them are editors of respected international scientific journals. Although recently developed biosensors utilize known principles, the biosensing devices described can significantly shorten the time required for successful detection and enhance efforts in more time-consuming directions, e.g. remote sensing systems and validation in real-sample analysis.The authors describe advances in all stages of biosensor development: theselection of biochemical components, their use in biosensor assembly, detection principles and improvements and applications for real sample assays.

Portable Chemical Sensors

Portable Chemical Sensors
Author: Dimitrios P. Nikolelis
Publisher: Springer Science & Business Media
Total Pages: 350
Release: 2012-02-02
Genre: Science
ISBN: 9400728727

Biosensors are making a large impact in environmental, food, biomedical, and other applications. In comparison to standard analytical detection methods, such as minimal sample preparation and handling, they offer advantages including real time detection, rapid detection of the analytes of concern, use of non-skilled personnel, and portability. The aim of this book is to focus on research related to the rapid detection of agents and weapons of bioterrorism and provide a comprehensive review of the research topics most pertinent to advancing devices applicable to the rapid real-time detection of toxicants such as microbes, pathogens, toxins, or nerve gases. The ongoing war on terrorism and the rising security concerns are driving the need for newer faster biosensors against bio-warfare agents for both military and civil defence applications. The volume brings together contributions from the most eminent international researchers in the field, covering various aspects of work not so far published in any scientific journal and often going beyond the “state of art “ . Readers of these review articles will learn new technological schemes that can lead to the construction of devices that will minimize the risk of bio-terrorism.

Commercial and Pre-Commercial Cell Detection Technologies for Defence Against Bioterror

Commercial and Pre-Commercial Cell Detection Technologies for Defence Against Bioterror
Author: L.M. Lechuga
Publisher: IOS Press
Total Pages: 180
Release: 2008-07-03
Genre: Medical
ISBN: 160750328X

As a response to the rapidly emerging threat of bioterrorism, the objectives of this volume on Commercial and Pre-Commercial Cell Detection Technologies for Defence against Bioterror are to exchange information on commercially available technologies and equipment for defense against bioterrorism; to further the development of new biosensor system prototypes into a commercially available apparatus and to explore human factors in BWA biosensors. The new commercial and pre-commercial technologies that are currently emerging in the world are presented and explained. Furthermore, there is a discussion about the interaction of modern detection systems with society and a trial for improvement of the relation between the scientific community and commercial entities. There are four major areas highlighted: the first is a presentation of the most advanced biosensors and biodetection system which can be found in the market or are quite close to commercialization. Systems as the BIOHAWKTM, SASS 2000, RAPTOR, Bionas® 2500, OWLS, or a portable SPR are presented in this section. The second issue is a presentation of the advances in the research of biodetection devices as DNA and protein microchips, micro and nanophotonic sensors, CMOS microsensor chips, electrochemical arrays, physical platforms, electro optical detection, mass detection, etc. Then, there is a description of the latest developments in the employment of bioreceptor layers for the selective detection of BWA, as protein signatures, molecular imprinted polymers, membrane engineering (MIME), cell signatures, monoclonal antibodies, synthetic antibodies and lytic phages, among others. The last part is the discussion of the human factor: societal issues related to sensor development and employment for BWA detection.

Biosensors in Food Safety and Quality

Biosensors in Food Safety and Quality
Author: Poonam Mishra
Publisher: CRC Press
Total Pages: 665
Release: 2022-04-25
Genre: Science
ISBN: 0429535538

Biosensors in food safety and quality have become indispensable in today’s world due to the requirement of food safety and security for human health and nutrition. This book covers various types of sensors and biosensors that can be used for food safety and food quality monitoring, but these are not limited to conventional sensors, such as temperature sensors, optical sensors, electrochemical sensors, calorimetric sensors, and pH sensors. The chapters are framed in a way that readers can experience the novel fabrication procedures of some advanced sensors, including lab-on-a-chip biosensors, IoT-based sensors, microcontroller-based sensors, and so on, particularly for fruits and vegetables, fermented products, plantation products, dairy-based products, heavy metal analysis in water, meat, fish, etc. Its simplistic presentation and pedagogical writing provide the necessary thrust and adequate information for beginners, scientists, and researchers. The book offers comprehensive coverage of the most essential topics, which include the following: Fundamentals of biosensors Overview of food safety and quality analysis Major toxicants of food and water Fabrication techniques of biosensors applicable for different segments of the food industry This book serves as a reference for scientific investigators who work on the assurance of food safety and security using biosensing principles as well as researchers developing biosensors for food analysis. It may also be used as a textbook for graduate-level courses in bioelectronics.

Recognition Receptors in Biosensors

Recognition Receptors in Biosensors
Author: Mohammed Zourob
Publisher: Springer Science & Business Media
Total Pages: 864
Release: 2010-01-08
Genre: Technology & Engineering
ISBN: 1441909192

Recognition receptors play a key role in the successful implementation of chemical and biosensors. Molecular recognition refers to non-covalent speci?c binding between molecules, one of which is typically a macromolecule or a molecular assembly, and the other is the target molecule (ligand or analyte). Biomolecular recognition is typically driven by many weak interactions such as hydrogen bo- ing, metal coordination, hydrophobic forces, van der Waals forces, pi-pi interactions and electrostatic interaction (due to permanent charges, dipoles, and quadrupoles) the polarization of charge distributions by the interaction partner leading to ind- tion and dispersion forces, and Pauli-exclusion-principle-derived inter-atomic repulsion, and a strong, “attractive” force arising largely from the entropy of the solvent and termed the hydrophobic effect. In recent years, there has been much progress in understanding the forces that drive the formation of such complexes, and how these forces are relate to the physical properties of the interacting molecules and their environment allows rational design of molecules and materials that interact in speci?c and desired ways. This book presents a signi?cant and up-to-date review of the various recognition elements, their immobilization, characterization techniques by a panel of dist- guished scientists. This work is a comprehensive approach to the recognition receptors area presenting a thorough knowledge of the subject and an effective integration of these receptors on sensor surfaces in order to appropriately convey the state-of the-art fundamentals and applications of the most innovative approaches.

Commercial Biosensors and Their Applications

Commercial Biosensors and Their Applications
Author: Mustafa Kemal Sezgintürk
Publisher: Elsevier
Total Pages: 374
Release: 2020-06-12
Genre: Science
ISBN: 0128196858

Commercial Biosensors and Their Applications: Clinical, Food, and Beyond offers professionals an in-depth look at some of the most significant applications of commercially available biosensor-based instrumentation in the clinical, food quality control, bioprocess monitoring, and bio threat fields. Featuring contributions by an international team of scientists, this book provides readers with an unparalleled opportunity to see how their colleagues around the world are using these powerful tools. This book is an indispensable addition to the reference libraries of biosensor technologists, analytical chemists, clinical chemists, biochemists, physicians, medical doctors, engineers, and clinical biochemists. The book discusses the need for portable, rapid, and smart biosensing devices and their use as cost-effective, in situ, real-time analytical tools in a variety of fields. Devotes several chapters to applications of biosensors to clinical samples, exploring how biosensors are currently used for in-home diabetes monitoring, point-of-care diagnostics, non-invasive sensing, and biomedical research Includes a section on food applications covering how biosensors can detect genetically modified organisms, toxins, allergens, hormones, microorganisms, species-specificity, pesticides, insecticides, and related components Discusses nanobiosensor and applications, including a chapter on nanotechnological approaches and materials in commercial biosensors

Biosensors

Biosensors
Author: Chandra Mouli Pandey
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 265
Release: 2019-03-04
Genre: Science
ISBN: 311063824X

This book focuses on the state-of-the-art of biosensor research and development for specialists and non-specialists. It introduces the fundamentals of the subject with relevant characteristics of transducer elements, as well as biochemical recognition molecules. This book is ideal for researchers of nanotechnology, materials science and biophysics.

Bio-Inspired Innovation and National Security

Bio-Inspired Innovation and National Security
Author: National Defense University
Publisher: NDU Press
Total Pages: 356
Release: 2010-10
Genre: History
ISBN: 1780390408

Despite the vital importance of the emerging area of biotechnology and its role in defense planning and policymaking, no definitive book has been written on the topic for the defense policymaker, the military student, and the private-sector bioscientist interested in the "emerging opportunities market" of national security. This edited volume is intended to help close this gap and provide the necessary backdrop for thinking strategically about biology in defense planning and policymaking. This volume is about applications of the biological sciences, here called "biologically inspired innovations," to the military. Rather than treating biology as a series of threats to be dealt with, such innovations generally approach the biological sciences as a set of opportunities for the military to gain strategic advantage over adversaries. These opportunities range from looking at everything from genes to brains, from enhancing human performance to creating renewable energy, from sensing the environment around us to harnessing its power.

Biosensors

Biosensors
Author: Rajmohan Joshi
Publisher: Gyan Publishing House
Total Pages: 324
Release: 2006
Genre: Biosensors
ISBN: 9788182053755

A biosensor is a device for the detection of an analyte that combines a biological component with a physiochemical detector component. A typical biosensor consists of three parts: a sensitive biological element, a transducer in between and a detector element. The most widespread example of a commercial biosensor is the blood glucose biosensor, which uses an enzyme to break blood glucose down. In so doing it transfers an electron to an electrode and this is converted into a measure of blood glucose concentration. The high market demand for such sensors has fuelled development of associated sensor technologies. This book covers recent developments that combine the fields of biotechnology and electrical engineering with applications in the detection of very low levels of chemicals and biological agents in the body. It provides an authentic overview of a wide range of biosensing systems, discussing the elements of different transducers used in sensors and the selective elements that are employed. The style is relatively non-mathematical and informal in approach. The contents of the book will be ideal for graduate and postgraduate students of biotechnology, analytical and physical chemistry. It will also be invaluable to all those concerned with the environmental and biomedical applications of such biosensing systems.

State of the Art in Biosensors

State of the Art in Biosensors
Author: Toonika Rinken
Publisher: BoD – Books on Demand
Total Pages: 326
Release: 2013-03-13
Genre: Science
ISBN: 9535110357

The main challenge in biosensor development is their application for various practical tasks to provide a continuous and reliable flow of information about the indicators of natural and industrial processes and the surroundings, so enabling adequate feedback and control. Biosensors can provide essential information, as the quality of life depends mainly on our knowledge about what we breathe, what we eat and how our bodies are able to metabolize the material, which we contact. This book includes 14 chapters, written by 52 authors and is focused on the applications of biosensors for monitoring the parameters of environment, the quality of food and biomarkers of health.