Biophysics of the Cochlea

Biophysics of the Cochlea
Author: Ernst Dalhoff
Publisher: World Scientific
Total Pages: 650
Release: 2003
Genre: Medical
ISBN: 9789812704931

This book contains the proceedings of an international hearing-research conference held in Germany 2002. The conference brought together experts in genetics, molecular and cellular biology, physiology, engineering, physics, mathematics, audiology and medicine to synthesize and extend our understanding of how the cochlea works. Topics are discussed experimentally and theoretically at the molecular, cellular and whole-organ levels. Some of the topics are: mechanosensitivity of motor proteins; mechanochemical transduction by motor proteins; mechanoelectrical transduction in the stereocilia of hair cells; electromechanical transduction in the stereocilia, soma and synapses of hair cells; multidimensional vibration of the organ of Corti; and otoacoustic emissions. This book will be invaluable to researchers and students in auditory science.

The Cochlea

The Cochlea
Author: Peter Dallos
Publisher: Springer Science & Business Media
Total Pages: 561
Release: 2012-12-06
Genre: Medical
ISBN: 1461207576

Knowledge about the structure and function of the inner ear is vital to an understanding of vertebrate hearing. This volume presents a detailed overview of the mammalian cochlea from its anatomy and physiology to its biophysics and biochemistry. The nine review chapters, written by internationally distinguished auditory researchers, provide a detailed and unified introduction to sound processing in the cochlea and the steps by which the ensuing signals are prepared for the central nervous system.

Cochlear Mechanics

Cochlear Mechanics
Author: Hendrikus Duifhuis
Publisher: Springer Science & Business Media
Total Pages: 266
Release: 2012-01-07
Genre: Medical
ISBN: 1441961178

The field of cochlear mechanics has received an increasing interest over the last few decades. In the majority of these studies the researchers use linear systems analysis or linear approximations of the nonlinear (NL) systems. Even though it has been clear that the intact cochlea operates nonlinearly, lack of tools for proper nonlinear analysis, and widely available tools for linear analysis still lead to inefficient and possibly incorrect interpretation of the biophysics of the cochlea. An example is the presumption that a change in cochlear stiffness at hair cell level must account for the observed change in tuning (or frequency mapping) due to prestin application. Hypotheses like this need to be addressed in a tutorial that is lucid enough to analyze and explain basic differences. Cochlear Mechanics presents a useful and mathematically justified/justifiable approach in the main part of the text, an approach that will be elucidated with clear examples. The book will be useful to scientists in auditory neuroscience, as well as graduate students in biophysics/biomedical engineering.

Mechanics of Hearing

Mechanics of Hearing
Author: E. de Boer
Publisher: Springer Science & Business Media
Total Pages: 214
Release: 2012-12-06
Genre: Technology & Engineering
ISBN: 9400969112

IUTAM/ICA Symposium, Delft, July 1983

Cochlear Mechanics

Cochlear Mechanics
Author: Frank Böhnke
Publisher: S. Karger AG (Switzerland)
Total Pages: 0
Release: 1999
Genre: Cochlea
ISBN: 9783805569880

This special issue collects our current knowledge of the mechanical processing of acoustic signals by the cochlea and its containing structures. Many workers in diverse disciplines in otology use the facts from cochlear mechanics for the interpretation of their results. Presented here for the first time is the development of a three-dimensional mechanical model of the curved cochlea including fluid-structure couplings. An important approach for future cochlear modeling is shown by the provision of geometrical data for the input of three-dimensional finite element models by microtomographic imaging. A remarkable article tries to demonstrate a connection between outer hair cell mechanics and the complex phenomenon of tinnitus and will be of special interest for stress engineers. Owing to its strong interdisciplinarity, this issue is not only intended for biophysicists, ENT clinicians and audiologists but also for radiologists, biomechanical engineers and computer engineers.

The Auditory System and Human Sound-Localization Behavior

The Auditory System and Human Sound-Localization Behavior
Author: John van Opstal
Publisher: Academic Press
Total Pages: 438
Release: 2016-03-29
Genre: Science
ISBN: 0128017252

The Auditory System and Human Sound-Localization Behavior provides a comprehensive account of the full action-perception cycle underlying spatial hearing. It highlights the interesting properties of the auditory system, such as its organization in azimuth and elevation coordinates. Readers will appreciate that sound localization is inherently a neuro-computational process (it needs to process on implicit and independent acoustic cues). The localization problem of which sound location gave rise to a particular sensory acoustic input cannot be uniquely solved, and therefore requires some clever strategies to cope with everyday situations. The reader is guided through the full interdisciplinary repertoire of the natural sciences: not only neurobiology, but also physics and mathematics, and current theories on sensorimotor integration (e.g. Bayesian approaches to deal with uncertain information) and neural encoding. - Quantitative, model-driven approaches to the full action-perception cycle of sound-localization behavior and eye-head gaze control - Comprehensive introduction to acoustics, systems analysis, computational models, and neurophysiology of the auditory system - Full account of gaze-control paradigms that probe the acoustic action-perception cycle, including multisensory integration, auditory plasticity, and hearing impaired

Cochlear Implants

Cochlear Implants
Author: Graeme Clark
Publisher: Springer Science & Business Media
Total Pages: 864
Release: 2006-04-18
Genre: Medical
ISBN: 0387215506

The cochlear implant is a device that bypasses a nonfunctional inner ear and stimulates the auditory nerve directly. Written by the "father" of the multi-electrode implant, this comprehensive text and reference gives an account of the principles underlying cochlear implants and their clinical application. For the clinician, the book will provide guidance in the treatment of patients; for the engineer and researcher it will provide the background for further research; and for the student, it will provide a through understanding of the subject.

From Sound to Synapse

From Sound to Synapse
Author: C. Daniel Geisler
Publisher:
Total Pages: 410
Release: 1998
Genre: Medical
ISBN: 9780195100259

This readable, well-illustrated text describes the exquisite job that the mammalian ear does in transforming sound into nerve impulses. The reader is led along the same pathway followed by an acoustic signal--from the outer ear, through the middle ear, and into the inner ear where the minuscule vibrations of the sound waves are transformed into nerve impulses. At each stage, the basic mechanisms are described qualitatively in terms of current theory and illustrated with experimental data.

Biophysics

Biophysics
Author: William Bialek
Publisher: Princeton University Press
Total Pages: 653
Release: 2012-12-17
Genre: Science
ISBN: 1400845572

A physicist's guide to the phenomena of life Interactions between the fields of physics and biology reach back over a century, and some of the most significant developments in biology—from the discovery of DNA's structure to imaging of the human brain—have involved collaboration across this disciplinary boundary. For a new generation of physicists, the phenomena of life pose exciting challenges to physics itself, and biophysics has emerged as an important subfield of this discipline. Here, William Bialek provides the first graduate-level introduction to biophysics aimed at physics students. Bialek begins by exploring how photon counting in vision offers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. He draws from these lessons three general physical principles—the importance of noise, the need to understand the extraordinary performance of living systems without appealing to finely tuned parameters, and the critical role of the representation and flow of information in the business of life. Bialek then applies these principles to a broad range of phenomena, including the control of gene expression, perception and memory, protein folding, the mechanics of the inner ear, the dynamics of biochemical reactions, and pattern formation in developing embryos. Featuring numerous problems and exercises throughout, Biophysics emphasizes the unifying power of abstract physical principles to motivate new and novel experiments on biological systems. Covers a range of biological phenomena from the physicist's perspective Features 200 problems Draws on statistical mechanics, quantum mechanics, and related mathematical concepts Includes an annotated bibliography and detailed appendixes

Hearing

Hearing
Author: Aage R. Moller
Publisher: Academic Press
Total Pages: 326
Release: 2000-05-25
Genre: Medical
ISBN: 0125042558

There is a new trend in the education of audiologists that emphasizes the basics of hearing--Hearing: Its Physiology and Pathophysiology addresses this trend. It covers not only the basics of hearing but also the basics of pathophysiology, which is not covered in a comprehensive way in any other text today. This book recognizes the fact that the diseased auditory system does indeed function, but in a different way than the normal system. Few books have addressed the pathophysiology of the ear and the auditory nervous system. Most books on hearing begin with a detailed description of the physics of sound, which scares many readers away because they believe they need to understand acoustics to understand how the ear functions. Hearing: Its Physiology and Pathophysiology does not assume that the readers are physicists, which would be analogous to assuming that visual physiologists would need to know quantum mechanics to understand how the visual nervous system functions. * This book provides a thorough understanding of the anatomy and function of the auditory system * To the basic scientist, it will provide an understanding of the auditory system and how it works * To the clinician, it will provide insight into the normal and diseased auditory system