Biomechanics In Tumor Cell Membrane Repairing Cancer Metastasis And T Cell Activation
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| Author | : Cheng Dong |
| Publisher | : Springer |
| Total Pages | : 378 |
| Release | : 2018-10-27 |
| Genre | : Medical |
| ISBN | : 3319952943 |
This book covers multi-scale biomechanics for oncology, ranging from cells and tissues to whole organ. Topics covered include, but not limited to, biomaterials in mechano-oncology, non-invasive imaging techniques, mechanical models of cell migration, cancer cell mechanics, and platelet-based drug delivery for cancer applications. This is an ideal book for graduate students, biomedical engineers, and researchers in the field of mechanobiology and oncology. This book also: Describes how mechanical properties of cancer cells, the extracellular matrix, tumor microenvironment and immuno-editing, and fluid flow dynamics contribute to tumor progression and the metastatic process Provides the latest research on non-invasive imaging, including traction force microscopy and brillouin confocal microscopy Includes insight into NCIs’ role in supporting biomechanics in oncology research Details how biomaterials in mechano-oncology can be used as a means to tune materials to study cancer
| Author | : John P. Bilezikian |
| Publisher | : Academic Press |
| Total Pages | : 2074 |
| Release | : 2008-09-29 |
| Genre | : Medical |
| ISBN | : 0080568750 |
Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. - Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field - The essential resource for anyone involved in the study of bones and bone diseases - Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics - Readers can easily search and locate information quickly as it will be online with this new edition
| Author | : Caterina A. M. La Porta |
| Publisher | : Cambridge University Press |
| Total Pages | : 187 |
| Release | : 2017-04-20 |
| Genre | : Science |
| ISBN | : 1108150330 |
Recent years have witnessed an increasing number of theoretical and experimental contributions to cancer research from different fields of physics, from biomechanics and soft-condensed matter physics to the statistical mechanics of complex systems. Reviewing these contributions and providing a sophisticated overview of the topic, this is the first book devoted to the emerging interdisciplinary field of cancer physics. Systematically integrating approaches from physics and biology, it includes topics such as cancer initiation and progression, metastasis, angiogenesis, cancer stem cells, tumor immunology, cancer cell mechanics and migration. Biological hallmarks of cancer are presented in an intuitive yet comprehensive way, providing graduate-level students and researchers in physics with a thorough introduction to this important subject. The impact of the physical mechanisms of cancer are explained through analytical and computational models, making this an essential reference for cancer biologists interested in cutting-edge quantitative tools and approaches coming from physics.
| Author | : Kursad Turksen |
| Publisher | : John Wiley & Sons |
| Total Pages | : 320 |
| Release | : 2018-02-21 |
| Genre | : Science |
| ISBN | : 1119282489 |
A comprehensive resource on the recent developments of stem cell use in wound healing With contributions from experts in the field, Wound Healing offers a thorough review of the most recent findings on the use of stem cells to heal wounds. This important resource covers both the basic and translational aspects of the field. The contributors reveal the great progress that has been made in recent years and explore a wide range of topics from an overview of the stem cell process in wound repair to inflammation and cancer. They offer a better understanding of the identities of skin stem cells as well as the signals that govern their behavior that contributes to the development of improved therapies for scarring and poorly healing wounds. Comprehensive in scope, this authoritative resource covers a wealth of topics such as: an overview of stem cell regeneration and repair, wound healing and cutaneous wound healing, the role of bone marrow derived stems cells, inflammation in wound repair, role and function of inflammation in wound repair, and much more. This vital resource: Provides a comprehensive overview of stem cell use in wound healing, including both the basic and translational aspects of the field Covers recent developments and emerging subtopics within the field Offers an invaluable resource to clinical and basic researchers who are interested in wound healing, stem cells, and regenerative medicine Contains contributions from leading experts in the field of wound healing and care Wound Healing offers clinical researchers and academics a much-needed resource written by noted experts in the field that explores the role of stem cells in the repair and restoration of healing wounds.
| Author | : Sam Thiagalingam |
| Publisher | : Cambridge University Press |
| Total Pages | : 597 |
| Release | : 2015-04-09 |
| Genre | : Mathematics |
| ISBN | : 0521493390 |
An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
| Author | : Francesco S. Pavone |
| Publisher | : Taylor & Francis |
| Total Pages | : 465 |
| Release | : 2016-04-19 |
| Genre | : Science |
| ISBN | : 1439849153 |
Second-harmonic generation (SHG) microscopy has shown great promise for imaging live cells and tissues, with applications in basic science, medical research, and tissue engineering. Second Harmonic Generation Imaging offers a complete guide to this optical modality, from basic principles, instrumentation, methods, and image analysis to biomedical a
| Author | : Claudia Mierke |
| Publisher | : Iph001 |
| Total Pages | : 500 |
| Release | : 2018-10-24 |
| Genre | : Science |
| ISBN | : 9780750317511 |
This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.
| Author | : Thorsten Cramer |
| Publisher | : Springer |
| Total Pages | : 272 |
| Release | : 2016-08-24 |
| Genre | : Medical |
| ISBN | : 3319421182 |
This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.
| Author | : Dmitry I. Gabrilovich |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 471 |
| Release | : 2014-02-10 |
| Genre | : Medical |
| ISBN | : 1489980563 |
Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never before been discussed in previous monographs. The last decades were characterized by substantial progress in the understanding of the role of the immune system in tumor progression. Researchers have learned how to manipulate the immune system to generate tumor specific immune response, which raises high expectations for immunotherapy to provide breakthroughs in cancer treatment. It is increasingly clear that tumor-induced abnormalities in the immune system not only hampers natural tumor immune surveillance, but also limits the effect of cancer immunotherapy. Therefore, it is critically important to understand the mechanisms of tumor-induced immune suppression to make any progress in the field and this monograph provides these important insights.
| Author | : Jamie A. Goode |
| Publisher | : John Wiley & Sons |
| Total Pages | : 322 |
| Release | : 2001-11-28 |
| Genre | : Science |
| ISBN | : 9780471499596 |
Several fundamentally important questions form the basis for this book. What are the relationships between tumour formation and tumour pH? What are the effects of tumour pH and hypoxia on carcinogenesis or tumorigenesis? What are the therapeutic consequences of tumour pH? It is hypothesised that low extracellular pH is not only an important consequence of tumour growth but may also promote further tumorigenic transformation. Furthermore, in vitro studies suggest that low pH strongly affects the efficacy of chemo- and radiotherapy. Better understanding of the influence of pH on tumour growth, coupled with manipulation of the pH of the tumour microenvironment, may lead to the development of more effective therapies.
