Biology And Signal Transduction Mechanisms Of Nerve Growth Factor Induced Apoptosis In Medulloblastomas
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| Author | : David A. Frank |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 358 |
| Release | : 2002-12-31 |
| Genre | : Medical |
| ISBN | : 1402073402 |
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
| Author | : |
| Publisher | : |
| Total Pages | : 790 |
| Release | : 2001 |
| Genre | : Dissertations, Academic |
| ISBN | : |
| Author | : |
| Publisher | : |
| Total Pages | : 816 |
| Release | : 2000 |
| Genre | : Dissertation abstracts |
| ISBN | : |
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 552 |
| Release | : 2017-02-15 |
| Genre | : Science |
| ISBN | : 0128122641 |
Neurotrophins, the latest volume in the Vitamins and Hormones series first published in 1943, and the longest-running serial published by Academic Press, provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions, and the biological actions of neurotrophins related to clinical conditions and disease. Each volume is thoroughly reviewed and focuses on a single molecule or disease that is related to vitamins or hormones, with the topic broadly interpreted to include related substances such as transmitters, cytokines, growth factors, and others. - Provides cutting-edge reviews concerning the molecular and cellular biology of vitamins and hormones - Contains expertise from world-renowned contributors - Focuses on a single molecule or disease that is related to vitamins or hormones, with the topic broadly interpreted to include related substances such as transmitters, cytokines, growth factors, and others - Presents in-depth, current information from the molecular to clinical level
| Author | : |
| Publisher | : |
| Total Pages | : 1398 |
| Release | : 1987 |
| Genre | : Medicine |
| ISBN | : |
| Author | : Hans J. ten Donkelaar |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 544 |
| Release | : 2006-09-07 |
| Genre | : Medical |
| ISBN | : 3540346597 |
Progress in developmental neurobiology and advances in (neuro) genetics have been spectacular. The high resolution of modern imaging techniques applicable to developmental disorders of the human brain and spinal cord have created a novel insight into the developmental history of the central nervous system (CNS). This book provides a comprehensive overview of the development of the human CNS in the context of its many developmental disorders. It provides a unique combination of data from human embryology, animal research and developmental neuropathology, and there are more than 400 figures in over a hundred separate illustrations.
| Author | : Georg F. Weber |
| Publisher | : Springer |
| Total Pages | : 486 |
| Release | : 2015-07-22 |
| Genre | : Medical |
| ISBN | : 3319132784 |
Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the topic of molecular therapies in cancer. A further deficit in the relevant literature is a progressive sub-specialization that typically limits textbooks on cancer drugs to cover either pharmacology or medicinal chemistry or signal transduction, rather than explaining molecular drug actions across all those areas; Molecular Therapies of Cancer fills this void. The book is divided into five sections: 1. Molecular Targeting of Cancer Cells; 2. Emerging and Alternative Treatment Modalities; 3. Molecular Targeting of Tumor-Host Interactions; 4. Anti-Cancer Drug Pharmacokinetics; and 5. Supportive Therapies.
| Author | : Carsten Nieder |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 308 |
| Release | : 2003 |
| Genre | : Medical |
| ISBN | : 9783540422310 |
This book describes and summarizes the radiation responses of both normal and neoplastic tissues with a focus on rational strategies for the modification of these responses. Emerging data from molecular oncology and radiobiology are reviewed in depth. The book covers not only general principles of radiation-induced reactions but also a large number of preclinical and clinical data that will guide the reader through this complex and dynamic field and will provide valuable information for the development of further research projects.
| Author | : |
| Publisher | : |
| Total Pages | : 1398 |
| Release | : 1994 |
| Genre | : Medicine |
| ISBN | : |
| Author | : |
| Publisher | : |
| Total Pages | : 2692 |
| Release | : 2002 |
| Genre | : Chemistry |
| ISBN | : |
