Biologically Modified Polymeric Biomaterial Surfaces
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Author | : Buddy D. Ratner |
Publisher | : Springer Science & Business Media |
Total Pages | : 214 |
Release | : 1997-02-28 |
Genre | : Medical |
ISBN | : 9780306455124 |
Proceedings of the American Chemical Society Division of Polymer Chemistry International Symposium held in Anaheim, California, April 2-6, 1995
Author | : E. Piskin |
Publisher | : Springer Science & Business Media |
Total Pages | : 191 |
Release | : 2012-12-06 |
Genre | : Technology & Engineering |
ISBN | : 9401118728 |
gap always exists between the material performance generation of new molecules along with the release during in-vivo animal tests and clinical situations, of substances from a multitude of cells. The plasma because of the difference in individual reactions proteins (including coagulation and complement proteins), the blood cells deposited on the material between one animal and another and humans. Likewise, sophisticated in-vitro and in-vivo models surface or circulating in the blood stream and their are being developed to study living body responses. released substances take part in the dynamic process of fibrinolysis and thrombus formation. Progress has been achieved in culturing mammalian cells, particularly human cells, which has lead to new in-vitro models to study cell-biomaterial Tissue response interactions. These techniques are discussed in the other chapters of this volume. Materials implanted in tissues always generate a response. The major tissue response in the extra BIOLOGICAL MODIFICATION vascular system is an inflammatory process, which may be induced chemically or physically. Many Surfaces of polymeric biomaterials may be modified proteins and cells are involved in this very complex by using a variety of biological entities (e.g.
Author | : Andreas Taubert |
Publisher | : John Wiley & Sons |
Total Pages | : 599 |
Release | : 2013-07-23 |
Genre | : Science |
ISBN | : 352764962X |
At the interface of biology, chemistry, and materials science, this book provides an overview of this vibrant research field, treating the seemingly distinct disciplines in a unified way by adopting the common viewpoint of surface science. The editors, themselves prolific researchers, have assembled here a team of top-notch international scientists who read like a "who's who" of biomaterials science and engineering. They cover topics ranging from micro- and nanostructuring for imparting functionality in a top-down manner to the bottom-up fabrication of gradient surfaces by self-assembly, from interfaces between biomaterials and living matter to smart, stimuli-responsive surfaces, and from cell and surface mechanics to the elucidation of cell-chip interactions in biomedical devices. As a result, the book explains the complex interplay of cell behavior and the physics and materials science of artificial devices. Of equal interest to young, ambitious scientists as well as to experienced researchers.
Author | : Maria Cristina Tanzi |
Publisher | : Woodhead Publishing |
Total Pages | : 503 |
Release | : 2017-06-20 |
Genre | : Technology & Engineering |
ISBN | : 0081007434 |
Characterization of Polymeric Biomaterials presents a comprehensive introduction on the topic before discussing the morphology and surface characterization of biomedical polymers. The structural, mechanical, and biological characterization is described in detail, followed by invaluable case studies of polymer biomaterial implants. With comprehensive coverage of both theoretical and experimental information, this title will provide scientists with an essential guide on the topic of these materials which are regularly used for clinical applications, such as implants and drug delivery devices. However, a range of novel polymers and the development and modification of existing medical polymers means that there is an ongoing need to satisfy particular design requirements. This book explains the critical and fundamentals methods to characterize polymer materials for biomedical applications. - Presents a self-contained reference on the characterization of polymeric biomaterials - Provides comprehensive information on how to characterize biomedical polymers in order to improve design and synthesis - Includes useful case studies that demonstrate the characterization of biomaterial implants
Author | : Severian Dumitriu |
Publisher | : CRC Press |
Total Pages | : 922 |
Release | : 2013 |
Genre | : Medical |
ISBN | : 142009470X |
The third edition of a bestseller, this comprehensive reference presents the latest polymer developments and most up-to-date applications of polymeric biomaterials in medicine. Expanded into two volumes, the first volume covers the structure and properties of synthetic and natural polymers as well as bioresorbable hybrid membranes, drug delivery systems, cell bioassay systems, and electrospinning for regenerative medicine. This substantially larger resource includes state-of-the-art research and successful breakthroughs in applications that have occurred in the last ten years.
Author | : Buddy D. Ratner |
Publisher | : Springer Science & Business Media |
Total Pages | : 200 |
Release | : 2013-06-29 |
Genre | : Science |
ISBN | : 1489919538 |
Applications of synthetic materials in medicine date back over 4000 year2. The Egyptians used linen as sutures. In the Roman Empire, gold was used in dentistry. Perhaps even earlier, ivory and bone may have been used in the body by practitioners of the healing arts. The historical origins of modem biomaterials science are also hard to precisely trace, but many of the ideas that define biomaterials as we know them today evolved in the late 1950s and early 1960s. Surface modification technology has played a prominent role in biomaterials science, and has paralleled the evolution of the modem field. In a symposium organized by the Artifical Heart Program of the NIH National Heart Institute and the Artificial Kidney program of the NIH National Institute of Arthritis and Metabolic Diseases, held in Atlantic City, New Jersey, in 1968, there were already a number of presentations on surface modification. Surface characterization at that time included scanning electron microscopy, ellipsometry, contact angle methods, and infrared internal reflection methods.
Author | : Gilson Khang |
Publisher | : CRC Press |
Total Pages | : 1480 |
Release | : 2017-06-26 |
Genre | : Medical |
ISBN | : 9814745138 |
Millions of patients suffer from end-stage organ failure or tissue loss annually, and the only solution might be organ and/or tissue transplantation. To avoid poor biocompatibility–related problems and donor organ shortage, however, around 20 years ago a new, hybridized method combining cells and biomaterials was introduced as an alternative to whole-organ and tissue transplantation for diseased, failing, or malfunctioning organs—regenerative medicine and tissue engineering. This handbook focuses on all aspects of intelligent scaffolds, from basic science to industry to clinical applications. Its 10 parts, illustrated throughout with excellent figures, cover stem cell engineering research, drug delivery systems, nanomaterials and nanodevices, and novel and natural biomaterials. The book can be used by advanced undergraduate- and graduate-level students of stem cell and tissue engineering and researchers in macromolecular science, ceramics, metals for biomaterials, nanotechnology, chemistry, biology, and medicine, especially those interested in tissue engineering, stem cell engineering, and regenerative medicine.
Author | : Sangamesh G. Kum bar |
Publisher | : Newnes |
Total Pages | : 421 |
Release | : 2014-01-21 |
Genre | : Technology & Engineering |
ISBN | : 0123972906 |
Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Due to this versatility they are rapidly replacing other classes of biomaterials such as ceramics or metals. As a result, the demand for biomedical polymers has grown exponentially and supports a diverse and highly monetized research community. Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical polymers are expected to achieve a CAGR of 9.8% until 2015, supporting a current research community of approximately 28,000+. Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field. Coverage extends across synthesis, characterization, design consideration and biomedical applications. The work supports scientists researching the formulation of novel polymers with desirable physical, chemical, biological, biomechanical and degradation properties for specific targeted biomedical applications. - Combines chemistry, biology and engineering for expert and appropriate integration of design and engineering of polymeric biomaterials - Physical, chemical, biological, biomechanical and degradation properties alongside currently deployed clinical applications of specific biomaterials aids use as single source reference on field. - 15+ case studies provides in-depth analysis of currently used polymeric biomaterials, aiding design considerations for the future
Author | : Severian Dumitriu |
Publisher | : CRC Press |
Total Pages | : 920 |
Release | : 2013-01-17 |
Genre | : Science |
ISBN | : 1420094718 |
Biomaterials have had a major impact on the practice of contemporary medicine and patient care. Growing into a major interdisciplinary effort involving chemists, biologists, engineers, and physicians, biomaterials development has enabled the creation of high-quality devices, implants, and drug carriers with greater biocompatibility and biofunctiona
Author | : Carlos Federico Jasso-Gastinel |
Publisher | : William Andrew |
Total Pages | : 233 |
Release | : 2016-09-14 |
Genre | : Technology & Engineering |
ISBN | : 0323443982 |
Modification of Polymer Properties provides, for the first time, in one title, the latest information on gradient IPNs and gradient copolymers. The book covers the broad range of polymer modification routes in a fresh, current view representing a timely addition to the technical literature of this important area. Historically, blends, copolymers, or filled polymers have been developed to meet specific properties, or to optimize the cost/properties relationship. Using the gradient structure approach with conventional radical polymerization, it has been shown that it is possible to optimize properties if appropriate gradients in the composition of copolymer chains are obtained. An overview of the gradient structure approach for designing polymers has not appeared in the recent literature and this title covers the different methods used to modify properties, offering the whole range of ways to modify polymers in just one volume and making this an attractive option for a wide audience of practitioners. The approach for each chapter is to explain the fundamental principles of preparation, cover properties modification, describe future research and applications as examples of materials that may be prepared for specific applications, or that are already in use, in present day applications. The book is for readers that have a basic background in polymer science, as well as those interested in the different ways to combine or modify polymer properties. - Provides an integrated view on how to modify polymer properties - Presents the entire panorama of polymer properties modification in one reference, covering the essential information in each topic - Includes the optimization of properties using gradients in polymers composition or structure