Biological Inorganic Chemistry
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| Author | : Robert R. Crichton |
| Publisher | : Elsevier |
| Total Pages | : 383 |
| Release | : 2007-12-11 |
| Genre | : Science |
| ISBN | : 0080556221 |
The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment. Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on.Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject.Many colour illustrations. Enables easier visualization of molecular mechanismsWritten by a single author. Ensures homgeneity of style and effective cross referencing between chapters
| Author | : Ivano Bertini |
| Publisher | : University Science Books |
| Total Pages | : 794 |
| Release | : 2007 |
| Genre | : Science |
| ISBN | : 9781891389436 |
Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.
| Author | : Robert R. Crichton |
| Publisher | : Elsevier |
| Total Pages | : 504 |
| Release | : 2019-09-10 |
| Genre | : Science |
| ISBN | : 0444642269 |
Practical Approaches to Biological Inorganic Chemistry, Second Edition, reviews the use of spectroscopic and related analytical techniques to investigate the complex structures and mechanisms of biological inorganic systems that contain metals. Each chapter presents an overview of the technique, including relevant theory, a clear explanation of what it is, how it works, and how the technique is actually used to evaluate biological structures. New chapters cover Raman Spectroscopy and Molecular Magnetochemistry, but all chapters have been updated to reflect the latest developments in discussed techniques. Practical examples, problems and many color figures are also included to illustrate key concepts. The book is designed for researchers and students who want to learn both the basics and more advanced aspects of key methods in biological inorganic chemistry. Presents new chapters on Raman Spectroscopy and Molecular Magnetochemistry, as well as updated figures and content throughout Includes color images throughout to enable easier visualization of molecular mechanisms and structures Provides worked examples and problems to help illustrate and test the reader’s understanding of each technique Written by leading experts who use and teach the most important techniques used today to analyze complex biological structures
| Author | : Stephen J. Lippard |
| Publisher | : University Science Books |
| Total Pages | : 444 |
| Release | : 1994 |
| Genre | : Medical |
| ISBN | : 9780935702729 |
The use of unnatural metals - which have been introduced into human biology as diagnostic probes and drugs - is another active area of tremendous medical significance.
| Author | : Robert R. Crichton |
| Publisher | : Academic Press |
| Total Pages | : 693 |
| Release | : 2018-05-23 |
| Genre | : Science |
| ISBN | : 0128117427 |
Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Third Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems. The fascinating world of the role of metals in biology, medicine and the environment has progressed significantly since the very successful Second Edition of the book published in 2012. Beginning with an overview of metals and selected nonmetals in biology, the book supports the interdisciplinary nature of this vibrant area of research by providing an introduction to basic coordination chemistry for biologists and structural and molecular biology for chemists. Having built this accessible foundation, the book progresses to discuss biological ligands for metal ions, intermediary metabolism and bioenergetics, and methods to study metals in biological systems. The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment. Now in its Third Edition, this popular and award-winning resource highlights recent exciting advances and provides a thorough introduction for both researchers approaching the field from a variety of backgrounds, as well as advanced students. Winner of a 2019 Textbook Excellence Award (Texty) from the Textbook and Academic Authors Association Includes a thorough survey of metals in biological systems: in the human body, in medicine and in the environment Previous winner (Second Edition) of the 2013 Textbook Excellence Award (Texty) from the Text and Academic Authors Association Features new sections: an overview of the different functions of essential metal ions; toxic metals in diagnosis and therapeutics; crystal and ligand field theory and their limitations; molecular orbital theory; genetic and molecular biological approaches to study metals; more complex cofactors and their biosynthesis; photosynthetic oxidation of water; man-made environmental pollution; and metals as poisons
| Author | : Enzo Alessio |
| Publisher | : John Wiley & Sons |
| Total Pages | : 625 |
| Release | : 2011-02-25 |
| Genre | : Science |
| ISBN | : 352763312X |
This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic.
| Author | : K. Hussain Reddy |
| Publisher | : New Age International |
| Total Pages | : 372 |
| Release | : 2007 |
| Genre | : Biomineralization |
| ISBN | : 9788122414370 |
The Coverage In This Book Is Organised In Terms Of The Syllabus Prescribed In Ugc Model Curriculum 2001 For Both Undergraduate And Postgraduate Students Of Chemistry And Biological Sciences.The Book Provides A Comprehensive And In-Depth Treatment Of The Subject. In Addition To Explaining The Basic Principles And Applications In Bioinorganic Chemistry, The Book Also Describes: * Photosynthesis. * Metal Complexes And Their Interaction With Nucleic Acids. * Effect Of Inorganic Pollutants On Biological Systems.The Book Would Serve As An Ideal Text For Students Of Chemistry And Biological Sciences. Researchers In Related Areas Would Find It An Extremely Useful Reference Source.
| Author | : Lawrence Que |
| Publisher | : Sterling Publishing Company |
| Total Pages | : 574 |
| Release | : 2000 |
| Genre | : Science |
| ISBN | : 9781891389023 |
This text provides detailed coverage of physical methods used in bioinorganic chemistry. By integrating theory with experimentation, and providing a more biological orientation, the book aims to serve as a major textbook for students of bioinorganic chemistry.
| Author | : Dieter Rehder |
| Publisher | : OUP Oxford |
| Total Pages | : 0 |
| Release | : 2014-03 |
| Genre | : Science |
| ISBN | : 9780199655199 |
Bioinorganic Chemistry provides a broad overview of this dynamic field, reviewing the key chemical elements that have important biological function, and exploring how the chemistry of these elements is central to the function of biological systems.
| Author | : Wolfgang Kaim |
| Publisher | : John Wiley & Sons |
| Total Pages | : 510 |
| Release | : 2013-08-01 |
| Genre | : Science |
| ISBN | : 1118659260 |
The field of Bioinorganic Chemistry has grown significantly in recent years; now one of the major sub-disciplines of Inorganic Chemistry, it has also pervaded other areas of the life sciences due to its highly interdisciplinary nature. Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, Second Edition provides a detailed introduction to the role of inorganic elements in biology, taking a systematic element-by-element approach to the topic. The second edition of this classic text has been fully revised and updated to include new structure information, emerging developments in the field, and an increased focus on medical applications of inorganic compounds. New topics have been added including materials aspects of bioinorganic chemistry, elemental cycles, bioorganometallic chemistry, medical imaging and therapeutic advances. Topics covered include: Metals at the center of photosynthesis Uptake, transport, and storage of essential elements Catalysis through hemoproteins Biological functions of molybdenum, tungsten, vanadium and chromium Function and transport of alkaline and alkaline earth metal cations Biomineralization Biological functions of the non-metallic inorganic elements Bioinorganic chemistry of toxic metals Biochemical behavior of radionuclides and medical imaging using inorganic compounds Chemotherapy involving non-essential elements This full color text provides a concise and comprehensive review of bioinorganic chemistry for advanced students of chemistry, biochemistry, biology, medicine and environmental science.
