Biological Clocks Rhythms And Oscillations
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| Author | : Daniel B. Forger |
| Publisher | : MIT Press |
| Total Pages | : 369 |
| Release | : 2024-08-06 |
| Genre | : Science |
| ISBN | : 0262552817 |
An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.
| Author | : Daniel B. Forger |
| Publisher | : MIT Press |
| Total Pages | : 369 |
| Release | : 2017-11-16 |
| Genre | : Science |
| ISBN | : 0262036770 |
An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.
| Author | : Vinod Kumar |
| Publisher | : Springer |
| Total Pages | : 663 |
| Release | : 2017-02-15 |
| Genre | : Science |
| ISBN | : 8132236882 |
This book is a concise, comprehensive and up-to-date account of fundamental concepts and potential applications of biological timekeeping mechanisms in animals and humans. It also discusses significant aspects of the organization and importance of timekeeping mechanisms in both groups. Divided into seven sections, it addresses important aspects including fundamental concepts; animal and human clocks; clock interactions; clocks and metabolism and immune functions; pineal, melatonin and timekeeping; and clocks, photoperiodism and seasonal behaviours. The book also focuses on biological clock applications in a 24x7 human society, particularly in connection with life-style associated disorders like obesity and diabetes. It is a valuable resource for advanced undergraduates, researchers and professionals engaged in the study of the science of biological timekeeping.
| Author | : Urs Albrecht |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 306 |
| Release | : 2010-01-23 |
| Genre | : Science |
| ISBN | : 1441912622 |
With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.
| Author | : Michelle L. Gumz |
| Publisher | : Springer |
| Total Pages | : 382 |
| Release | : 2016-02-29 |
| Genre | : Medical |
| ISBN | : 1493934503 |
This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy’s potential for reducing cardiovascular risk. Offering a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease.
| Author | : Christopher S. Colwell |
| Publisher | : John Wiley & Sons |
| Total Pages | : 405 |
| Release | : 2015-07-07 |
| Genre | : Medical |
| ISBN | : 1118467787 |
Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease. Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration. Written in an accessible and informative style, Circadian Rhythms: Health and Disease,will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology.
| Author | : Paolo Sassone-Corsi |
| Publisher | : Springer |
| Total Pages | : 141 |
| Release | : 2016-04-04 |
| Genre | : Medical |
| ISBN | : 3319270699 |
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
| Author | : Leon Kreitzman |
| Publisher | : Profile Books |
| Total Pages | : 288 |
| Release | : 2011-09-30 |
| Genre | : Science |
| ISBN | : 1847653723 |
Popular science at its most exciting: the breaking new world of chronobiology - understanding the rhythm of life in humans and all plants and animals. The entire natural world is full of rhythms. The early bird catches the worm -and migrates to an internal calendar. Dormice hibernate away the winter. Plants open and close their flowers at the same hour each day. Bees search out nectar-rich flowers day after day. There are cicadas that can breed for only two weeks every 17 years. And in humans: why are people who work anti-social shifts more illness prone and die younger? What is jet-lag and can anything help? Why do teenagers refuse to get up in the morning, and are the rest of us really 'larks' or 'owls'? Why are most people born (and die) between 3am-5am? And should patients be given medicines (and operations) at set times of day, because the body reacts so differently in the morning, evening and at night? The answers lie in our biological clocks the mechanisms which give order to all living things. They impose a structure that enables us to change our behaviour in relation to the time of day, month or year. They are reset at sunrise and sunset each day to link astronomical time with an organism's internal time.
| Author | : Stefano Mancuso |
| Publisher | : Springer |
| Total Pages | : 405 |
| Release | : 2015-06-29 |
| Genre | : Science |
| ISBN | : 331920517X |
This second edition of a well-received book focuses on rhythmic behaviour in plants, which regulates all developmental and adaptive responses and can thus be regarded as quintessential to life itself. The chapters provide a timely update on recent advances in this field and comprehensively summarize the current state of knowledge concerning the molecular and physiological mechanisms behind circadian and ultradian oscillations in plants, their physiological implications for growth and development and adaptive responses to a dynamic environment. Written by a diverse group of leading researchers, the book will spark the interest of readers from many branches of science: from physicists and chemists wishing to learn about the multi-faceted rhythms in plants, to biologists and ecologists involved in the state-of-the-art modelling of complex rhythmic phenomena.
| Author | : Pavol Svorc |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 109 |
| Release | : 2019-12-18 |
| Genre | : Medical |
| ISBN | : 1789849004 |
The regular alternation of light and dark affects not only human biological systems, but also the social organization of behavior. The effect of such light modes is manifested in periodic changes in physiological functions and biological rhythms exhibited at every level of life. The book discusses some of the specificities of the circadian rhythms in living organisms and mentions aspects of the control of circadian rhythms as well as experimental and clinical cases that are closely related to circadian disruption. This book can evoke interest in many researchers who want to use this information for the advancement of their research towards a better understanding of the biological time structure.
