Biological And Biomechanical Performance Of Biomaterials
Download Biological And Biomechanical Performance Of Biomaterials full books in PDF, epub, and Kindle. Read online free Biological And Biomechanical Performance Of Biomaterials ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
| Author | : Jean-Pierre Boutrand |
| Publisher | : Woodhead Publishing |
| Total Pages | : 592 |
| Release | : 2019-11-21 |
| Genre | : Technology & Engineering |
| ISBN | : 0081026447 |
Biocompatibility and Performance of Medical Devices, Second Edition, provides an understanding of the biocompatibility and performance tests for ensuring that biomaterials and medical devices are safe and will perform as expected in the biological environment. Sections cover key concepts and challenges faced in relation to biocompatibility in medical devices, discuss the evaluation and characterization of biocompatibility in medical devices, describe preclinical performance studies for bone, dental and soft tissue implants, and provide information on the regulation of medical devices in the European Union, Japan and China. The book concludes with a review of histopathology principles for biocompatibility and performance studies. - Presents diverse insights from experts in government, industry and academia - Delivers a comprehensive overview of testing and interpreting medical device performance - Expanded to include new information, including sections on managing extractables, accelerating and simplifying medical device development through screening and alternative biocompatibility methods, and quality strategies which fasten device access to market
| Author | : Mangal Roy |
| Publisher | : Elsevier Inc. Chapters |
| Total Pages | : 19 |
| Release | : 2013-03-12 |
| Genre | : Science |
| ISBN | : 0128071036 |
In joint replacement surgery with suboptimal bone, allograft materials are often used to achieve biological fixation of the metallic implant to the host bone and reducing the implant fixation time. The most commonly used techniques are cemented and hydroxyapatite (HA)-coated metallic implants. Typically, HA coatings are suggested for patients with better bone stock, whereas recommended implant fixation process for most other osteoporotic patients is bone cements. In general, there is a long-standing need to improve the performance of hip and other devices for longer in vivo implant lifetime that can help in reducing the number of revision surgeries, as well as minimizing physical and mental trauma to the patient. To achieve these goals, it is important to understand the mechanical and biological properties of coatings that can influence not only its short- and long-term bioactivity but also life span in vivo. Over the years, it has been recognized that the stability of a coated implant is governed by its physical and mechanical properties. A coating that separates from the implant provides no advantage over an uncoated implant and undesirable due to problems with debris materials, which can lead to osteolysis. Therefore, it is important to properly characterize the coated implants in terms of its physical and mechanical properties. In this chapter, specific details on coating characterization techniques including sample dimensions, sample preparation, experimental procedure and data interpretation are discussed. In particular, the standards and requirements of regulatory organizations are presented elucidating the significance and use of each characterization. It is important to appreciate that mechanical properties of coatings can only be determined with certain coating specification such as coating thickness. This chapter is designed even for non-experts to follow mechanical property characterizations of coatings on medical implants.
| Author | : Jonathan Black |
| Publisher | : CRC Press |
| Total Pages | : 526 |
| Release | : 2005-12-20 |
| Genre | : Medical |
| ISBN | : 9780849339592 |
Bioengineers need a thorough grounding in biocompatibility - the biological performance of materials. Until now, there were no publications suitable for a neophyte in the field; prior publications were either not comprehensive or focused on rather narrow interests. Drawing on the author's 35 years of experience as a teacher, researcher, and consultant in biomaterials science and engineering (BSE), Biological Performance of Materials: Fundamentals of Biocompatibility, Fourth Edition focuses primarily on principles of biological performance at a relatively fundamental level, analyzing interactions between living organisms and nonliving materials used in medical devices - the subject that sets BSE apart as a distinct field of investigation. Following an introductory section, the book is divided into three sections: the material response to biological systems, host response to biomaterials, and test methods for determining biological response in vitro as well as in animal models and clinical settings. Supplemental "Interparts" summarize the physical properties of commonly used metallic, polymeric, and ceramic biomaterials. They also provide a guide to understanding the clinical performance of implanted biomaterials.
| Author | : Johanna Buschmann |
| Publisher | : Woodhead Publishing |
| Total Pages | : 352 |
| Release | : 2017-05-10 |
| Genre | : Technology & Engineering |
| ISBN | : 0081004923 |
Biomechanics of Tendons and Ligaments: Tissue Reconstruction looks at the structure and function of tendons and ligaments. Biological and synthetic biomaterials for their reconstruction and regeneration are reviewed, and their biomechanical performance is discussed. Regeneration tendons and ligaments are soft connective tissues which are essential for the biomechanical function of the skeletal system. These tissues are often prone to injuries which can range from repetition and overuse, to tears and ruptures. Understanding the biomechanical properties of ligaments and tendons is essential for their repair and regeneration. - Contains systematic coverage on how both healthy and injured tendons and ligaments work - Includes coverage of repair and regeneration strategies for tendons and ligaments - Presents an Interdisciplinary analysis on the topic
| Author | : Christopher Siedlecki |
| Publisher | : Woodhead Publishing |
| Total Pages | : 486 |
| Release | : 2018-03-05 |
| Genre | : Science |
| ISBN | : 0081004990 |
Hemocompatibility of Biomaterials for Clinical Applications: Blood-Biomaterials Interactions summarizes the state-of-the-art on this important subject. The first part of the book reviews the latest research on blood composition and response, mechanisms of coagulation, test standards and methods. Next, the book assesses techniques for modifying biomaterial surfaces and developing coatings to improve hemocompatibility. In the final sections, users will find discussions on ways to improve the hemocompatibility of particular classes of biomaterials and a review of methods for improving medical devices. - Provides comprehensive information on the fundamentals of hemocompatibility and new technologies - Combines research in the biomaterials field in a digestible format for clinical applications - Provides a complete overview biomaterials in current use and test methods
| Author | : Amirhossein Goharian |
| Publisher | : Elsevier |
| Total Pages | : 421 |
| Release | : 2017-03-15 |
| Genre | : Technology & Engineering |
| ISBN | : 0128047585 |
Trauma Plating Systems is the first reference and systematic book in the topic of trauma plating system in view of biomechanical, material, biological, and clinical aspects. The effects of these aspects on effectiveness of trauma plating fixation are deeply reviewed, discussed, and challenged from which promising evaluation and development concepts are explored. This book is divided into five sections: Section I covers general concepts of biomechanical, material, biological, and clinical aspects. Then it provides fundamentals of trauma plating systems, principles of biomechanical evaluation methods, and biomechanics of plating fixation in Section II. Section III reviews current metallic materials with their advantages and disadvantages in plating fixation of bone fractures and new promising materials with their potential benefits to enhance the effectiveness of plating fixation. Section IV represents currently concerned biomechanical-clinical challenges of plating fixation for various bone fractures, and Section V presents current and new development concepts of this type of trauma implants. This book as an accessible and easy usable textbook for various disciplines of audiences who are dealing with trauma plating system and fixation such as orthopedic surgeons, trauma implant manufacturers, biomechanical researchers, biomaterial researchers, and all biomedical or medical students and residents in different levels of education. Author has been diligent in both engineering and research environments in terms of research, testing, analysis, validation, verification, clinical studies, and technical writing. His main interest and effort is to integrate biomechanical, material, biological, and clinical requirements of orthopedic implants for creation of novel design conception in this industry. He has developed the website http://orthoimplant-development.com/ for further communication in development of orthopedic implants. - Smooth writing style for effective following, fast reading, and easy accessibility of the content - Detailed and insight reviews, discussions, and new ideas in evaluation methods and design conception - Disclosing of a novel conceptual plating system (Advance Healing Fixation System—AHealFS) with advanced biomechanical and clinical benefits in various stages of healing period potential to bring an interesting science breakthrough in fixation of bone fractures
| Author | : William Murphy |
| Publisher | : Springer |
| Total Pages | : 676 |
| Release | : 2016-06-11 |
| Genre | : Technology & Engineering |
| ISBN | : 1493933051 |
This book provides tabular and text data relating to normal and diseased tissue materials and materials used in medical devices. Comprehensive and practical for students, researchers, engineers, and practicing physicians who use implants, this book considers the materials aspects of both implantable materials and natural tissues and fluids. Examples of materials and topics covered include titanium, elastomers, degradable biomaterials, composites, scaffold materials for tissue engineering, dental implants, sterilization effects on material properties, metallic alloys, and much more. Each chapter author considers the intrinsic and interactive properties of biomaterials, as well as their appropriate applications and historical contexts. Now in an updated second edition, this book also contains two new chapters on the cornea and on vocal folds, as well as updated insights, data, and citations for several chapters.
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 2069 |
| Release | : 2018-09-01 |
| Genre | : Science |
| ISBN | : 0128051442 |
Encyclopedia of Biomedical Engineering, Three Volume Set is a unique source for rapidly evolving updates on topics that are at the interface of the biological sciences and engineering. Biomaterials, biomedical devices and techniques play a significant role in improving the quality of health care in the developed world. The book covers an extensive range of topics related to biomedical engineering, including biomaterials, sensors, medical devices, imaging modalities and imaging processing. In addition, applications of biomedical engineering, advances in cardiology, drug delivery, gene therapy, orthopedics, ophthalmology, sensing and tissue engineering are explored. This important reference work serves many groups working at the interface of the biological sciences and engineering, including engineering students, biological science students, clinicians, and industrial researchers. Provides students with a concise description of the technologies at the interface of the biological sciences and engineering Covers all aspects of biomedical engineering, also incorporating perspectives from experts working within the domains of biomedicine, medical engineering, biology, chemistry, physics, electrical engineering, and more Contains reputable, multidisciplinary content from domain experts Presents a ‘one-stop’ resource for access to information written by world-leading scholars in the field
| Author | : |
| Publisher | : ASM International |
| Total Pages | : 453 |
| Release | : 2009-01-01 |
| Genre | : |
| ISBN | : 1615031359 |
"The Materials Information Society, MPMD-Materials and Processes for Medical Devices."
| Author | : Henri Bourg |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2010 |
| Genre | : Biomedical engineering |
| ISBN | : 9781608764761 |
Despite the huge impact that biomaterials have had on patients' quality of life, improvements in device performance and the development of alternatives to augment available therapies are continuously being sought. This book explores the development and application of biomaterials over the past 25 years, examining the current clinical demand, the scientific rationale, and the technical challenges to be overcome. Furthermore, this book introduces the blood components involved in hemostasis and thrombosis, followed by the common biomaterials applied in blood-contacting devices. The complications induced by the interactions between blood and biomaterials is also briefly addressed, as well as the commonly used techniques for improving biomaterials' hemocompatibility. In addition, the authors give some valuable insight into calcium orthophosphate cements and concretes, as excellent biomaterials suitable for both dental and bone grafting application. Despite the growth of potential hydrogel based therapies, the route to market for new products is constrained by the need to develop an appropriate regulatory and metrological framework under which they will be assessed. This book outlines the role that metrology has to play in the regulation of emerging hydrogel-based therapies and detail possible strategies for assessing their safety and effectiveness. Other chapters examine the surface of CoCrMo alloy prior and after exposure into different solutions simulating oral conditions, recent research on delivery of gold nanoparticles inside the cells and their potential applications in nanomedicine, and the widely used biomedical applications for hydrogels.
