Biological Activity Of Natural Products
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Author | : Jaroslava Švarc-Gajić |
Publisher | : Nova Science Publishers |
Total Pages | : 0 |
Release | : 2013 |
Genre | : Health & Fitness |
ISBN | : 9781628089264 |
Many thousands of years ago, humans were introduced to the toxicants of minerals and plants of microbial origin, and since that time, natural bioactive compounds have been used in traditional medicine for treating different health conditions, but also as aphrodisiacs and as a means of suicide or murder. Modern medicine acknowledges natural bioactive compounds as valuable medicinal sources for both diagnostic and curative purposes. Natural compounds serve as templates for the production of new drugs with improved pharmacological properties. This book explains the term bioactivity and deals with the bioactive compounds of plants, animals, microbial and marine origin. Their use by traditional medicinal approach, as well as by modern medicine is further elaborated. Both beneficial and toxic properties of different chemical classes, including alkaloids, peptides, terpenoids, bioactive amines etc., are described. Their isolation at the industrial scale is presented through several technological processes which are explained in detail for several compound classes. The research explains how natural sources can be exploited my modern and traditional medicine, and presents the risks and benefits associated with their use. In addition, a new approach to studying bioactivity, that includes computational modelling and softwares for in silico description and prediction, is explained. A chemometric approach to studying bioactivity is demonstrated through several models given for some natural bioactive compounds and their derivatives.
Author | : Atta-ur- Rahman |
Publisher | : Elsevier |
Total Pages | : 421 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 0444595155 |
Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 37 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable source for researchers and engineers working in natural products and medicinal chemistry. - Describes the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - A valuable source for researchers and engineers working in natural product and medicinal chemistry
Author | : Goutam Brahmachari |
Publisher | : John Wiley & Sons |
Total Pages | : 544 |
Release | : 2015-03-23 |
Genre | : Science |
ISBN | : 3527337946 |
Ein multidisziplinärer Überblick über die aktuellen Themen und Zukunftstrends in der Erforschung von Naturstoffen mit Schwerpunkt auf pharmazeutischen und medizinischen Anwendungen.
Author | : Goutam Brahmachari |
Publisher | : World Scientific |
Total Pages | : 695 |
Release | : 2012 |
Genre | : Science |
ISBN | : 9814335371 |
Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.
Author | : Anne E. Osbourn |
Publisher | : Springer Science & Business Media |
Total Pages | : 588 |
Release | : 2009-07-07 |
Genre | : Science |
ISBN | : 0387854983 |
Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.
Author | : H.K. Wagner |
Publisher | : Springer Science & Business Media |
Total Pages | : 299 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3642666825 |
The fact that, of the approximately 600,000 plant species existing on the earth, only some 5 % have been specifically investigated chemically or pharmacologi cally, is a challenge to chemists spezializing in na tural substances and to pharmacologists. In view of the limited number of research capacities and the ever diminishing financial means, this challenge can only be met if, together with an improvement and refinement of methods of analysis, medicinal plant research is carried out on a broader interdisciplinary basis, with comparable, scientifically recognized screening methods, and if it is better coordinated, with greater use of modern documentation means. It is thus necessary in the future to concentrate specifically on projects leading to the development of new medicinal prepara tions. The plenary lectures hold in the present symposium of the 1st International Congress for Research on Medi cinal Plants reflect these efforts and tendencies. At the same time they provide a survey of some of the fields of medicinal plant research which are at present most actual and most intensively researched. They range from plant screening, isolation and structure eluci dation of new principles, to the therapeutical opti mization of a natural product. The lectures given at this congress show clearly the necessity, in addition to national phytochemical so cieties, for a central international organisation, in which all active medicinal plant researchers in the world are included. Their aim should be to provide the impulse for more optimal, rational research, aimed at the solution of specific projects.
Author | : Raffaele Pezzani |
Publisher | : |
Total Pages | : 296 |
Release | : 2021 |
Genre | : |
ISBN | : 9783036503059 |
Phytotherapy is probably the oldest form of medicine; however, it represents a new therapeutic tool for healthcare workers. Indeed plants are an infinite source of novel molecules, with countless possible combinations. This collection of articles (a Special Issue from Molecules) brings together the most up-to-date studies on the use of plant-derived compounds, ranging from their anti-inflammatory, antioxidant, and anticancer effects to the revision of the prominent literature.
Author | : J. Mulzer |
Publisher | : Springer Science & Business Media |
Total Pages | : 363 |
Release | : 2013-04-17 |
Genre | : Medical |
ISBN | : 3662040425 |
Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products. Total synthesis of natural products with interesting biological activities is paving the way for the preparation of new and improved analogs. The methods of combinatorial chemistry permit the selection of the best drug from a large number of candidates. Beyond synthesis and evaluation of organic molecules a number of new bioorganic methods are coming to the fore and will be discucced in this isue of the ERnst schering Research Foundation workshop proceedings.
Author | : Ana M. L Seca |
Publisher | : |
Total Pages | : 206 |
Release | : 2020 |
Genre | : |
ISBN | : 9783039366187 |
Nature represents an amazing source of inspiration, since it produces a great diversity of natural compounds selected by evolution, which exhibit multiple biological activities and applications. A large and very active research field is dedicated to identifying biosynthesized compounds, to improve/develop new methodologies, to produce/reuse natural compounds, and to assess their potential for pharmaceutical, cosmetic and food industries, among others, and additionally, to understand their mechanism of action. This book is dedicated to presenting the most recent results on the development of natural compounds' applications. Ten original research works, organized by applications, and two reviews are included. Each of them contributes to the knowledge advance, insofar as they present new applications for known products, new methodologies to obtain new products, or the evaluation of a given application, with the applications related to health promotion being the most frequently considered. These works are significant contributions and reinforce the dynamic field of natural products' applications.
Author | : Jie Jack Li |
Publisher | : Springer Science & Business Media |
Total Pages | : 292 |
Release | : 2013-03-14 |
Genre | : Science |
ISBN | : 3642340652 |
'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.