Bioinformatics From Nucleic Acids And Proteins To Cell Metabolism
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| Author | : Dietmar Schomburg |
| Publisher | : John Wiley & Sons |
| Total Pages | : 205 |
| Release | : 2008-09-26 |
| Genre | : Science |
| ISBN | : 3527615180 |
Bioinformatics, in this context the application of computer science to biological problems, has become an indispensable part of any research in the biosciences. Rapid developments in gene sequencing, structure determination as well as rational protein engineering and design have made it necessary for biologists, chemists, and computer scientists to channel their expertise into large scale collaborative projects. This GBF Monograph gives a general overview of the latest versatile activities in bioinformatics: * Biological Data Bases * DNA and RNA * Protein Sequences and Structures * From Molecules to Cell Metabolism The articles have been selected from contributions to a conference on Bioinformatics/Computer Application in the Biosciences, held in October 1995 in Braunschweig at the German National Research Center for Biotechnology.
| Author | : |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2002 |
| Genre | : Cells |
| ISBN | : 9780815332183 |
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 354 |
| Release | : 2012-09-13 |
| Genre | : Science |
| ISBN | : 0309224187 |
Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
| Author | : Dietmar Schomburg |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 660 |
| Release | : 2003-06-18 |
| Genre | : Science |
| ISBN | : 9783540005193 |
The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized – and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement Volumes.
| Author | : Valeria Mapelli |
| Publisher | : Humana Press |
| Total Pages | : 0 |
| Release | : 2014-04-18 |
| Genre | : Science |
| ISBN | : 9781493905621 |
Yeast Metabolic Engineering: Methods and Protocols provides the widely established basic tools used in yeast metabolic engineering, while describing in deeper detail novel and innovative methods that have valuable potential to improve metabolic engineering strategies in industrial biotechnology applications. Beginning with an extensive section on molecular tools and technology for yeast engineering, this detailed volume is not limited to methods for Saccharomyces cerevisiae, but describes tools and protocols for engineering other yeasts of biotechnological interest, such as Pichia pastoris, Hansenula polymorpha and Zygosaccharomyces bailii. Tools and technologies for the investigation and determination of yeast metabolic features are described in detail as well as metabolic models and their application for yeast metabolic engineering, while a chapter describing patenting and regulations with a special glance at yeast biotechnology closes the volume. Written in the highly successful Methods in Molecular Biology series format, most chapters include an introduction to their respective topic, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Yeast Metabolic Engineering: Methods and Protocols aims to familiarize researchers with the current state of these vital and increasingly useful technologies.
| Author | : Kazuhiko Nakatani |
| Publisher | : Springer |
| Total Pages | : 280 |
| Release | : 2016-04-04 |
| Genre | : Science |
| ISBN | : 3319271113 |
This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
| Author | : National Research Council |
| Publisher | : National Academies |
| Total Pages | : 471 |
| Release | : 1989-01-01 |
| Genre | : Science |
| ISBN | : 0309039274 |
Biology has entered an era in which interdisciplinary cooperation is at an all-time high, practical applications follow basic discoveries more quickly than ever before, and new technologiesâ€"recombinant DNA, scanning tunneling microscopes, and moreâ€"are revolutionizing the way science is conducted. The potential for scientific breakthroughs with significant implications for society has never been greater. Opportunities in Biology reports on the state of the new biology, taking a detailed look at the disciplines of biology; examining the advances made in medicine, agriculture, and other fields; and pointing out promising research opportunities. Authored by an expert panel representing a variety of viewpoints, this volume also offers recommendations on how to meet the infrastructure needsâ€"for funding, effective information systems, and other supportâ€"of future biology research. Exploring what has been accomplished and what is on the horizon, Opportunities in Biology is an indispensable resource for students, teachers, and researchers in all subdisciplines of biology as well as for research administrators and those in funding agencies.
| Author | : Ralf Hofestädt |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 244 |
| Release | : 1997-08-06 |
| Genre | : Computers |
| ISBN | : 9783540633709 |
This book constitutes the strictly refereed post-workshop proceedings of the German Conference on Bioinformatics, GCB'96, held in Leipzig, Germany, in September/October 1996. The volume presents 18 revised full papers together with three invited papers; these contributions were selected after a second round of reviewing from the 91 conference presentations. The book addresses current issues in computational biology and biologically inspired computing. The papers are organized in sections on biological and metabolic pathways, sequence analysis, molecular modeling, visualization, and formal languages, and DNA.
| Author | : S. Ignacimuthu |
| Publisher | : Alpha Science Int'l Ltd. |
| Total Pages | : 212 |
| Release | : 2005 |
| Genre | : Computers |
| ISBN | : 9781842652312 |
"This book is intended to give the basics of biological concepts, biological database and internet based bioinformatic tools. We are hopeful that this book will cater to the immediate needs of students, researchers, faculty members and pharmaceutical industries."--Pref.
| Author | : Julianne Zedalis |
| Publisher | : |
| Total Pages | : 1923 |
| Release | : 2017-10-16 |
| Genre | : Biology |
| ISBN | : 9781947172401 |
Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.
