Basic Principles of Formulation Types

Basic Principles of Formulation Types
Author: Tharwat F. Tadros
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 324
Release: 2018-05-22
Genre: Science
ISBN: 3110587963

Volume 2 of Formulation Science and Technology is a survey of the different types of formulations used in the chemical industry and offers numerous real-world examples of foams, gels, latexes etc. It offers in-depth explanations for research scientists, universities, and industry practitioners looking for a complete understanding of which type formulation works best for a certain application and why.

Essential Chemistry for Formulators of Semisolid and Liquid Dosages

Essential Chemistry for Formulators of Semisolid and Liquid Dosages
Author: Vitthal S. Kulkarni
Publisher: Academic Press
Total Pages: 256
Release: 2015-10-15
Genre: Science
ISBN: 012801072X

A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosity, microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations. - Unique coverage of the underlying chemistry that makes possible stable dosages - Quality content written by experienced experts from the drug development industry - Valuable information for academic and industrial scientists developing topical and liquid dosage formulations for pharmaceutical as well as skin care and cosmetic products

Pharmaceutical Formulation

Pharmaceutical Formulation
Author: Geoffrey D Tovey
Publisher: Royal Society of Chemistry
Total Pages: 432
Release: 2018-06-25
Genre: Medical
ISBN: 1849739412

Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product. Modern formulation science deals with biologics as well as small molecules. Regulatory and quality demands, in addition to advances in processing technologies, result in growing challenges as well as possibilities for the field. Pharmaceutical Formulation provides an up to date source of information for all who wish to understand the principles and practice of formulation in the drug industry. The book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. The first chapters introduce readers to different dosage forms, including oral liquid products, topical products and solid dosage forms such as tablets and capsules. Subsequent chapters cover pharmaceutical coatings, controlled release drug delivery and dosage forms designed specifically for paediatric and geriatric patients. The final chapter provides an introduction to the vital role intellectual property plays in drug development. Covering modern processing methods and recent changes in the regulatory and quality demands of the industry, Pharmaceutical Formulation is an essential, up to date resource for students and researchers working in academia and in the pharmaceutical industry.

Dosage Form Design Parameters

Dosage Form Design Parameters
Author:
Publisher: Academic Press
Total Pages: 816
Release: 2018-07-25
Genre: Medical
ISBN: 012814422X

Dosage Form Design Parameters, Volume II, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. - Examines the history and recent developments in drug dosage forms for pharmaceutical sciences - Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism - Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design

Developing Solid Oral Dosage Forms

Developing Solid Oral Dosage Forms
Author: Yihong Qiu
Publisher: Academic Press
Total Pages: 976
Release: 2009-03-10
Genre: Medical
ISBN: 008093272X

Developing Solid Oral Dosage Forms is intended for pharmaceutical professionals engaged in research and development of oral dosage forms. It covers essential principles of physical pharmacy, biopharmaceutics and industrial pharmacy as well as various aspects of state-of-the-art techniques and approaches in pharmaceutical sciences and technologies along with examples and/or case studies in product development. The objective of this book is to offer updated (or current) knowledge and skills required for rational oral product design and development. The specific goals are to provide readers with: - Basics of modern theories of physical pharmacy, biopharmaceutics and industrial pharmacy and their applications throughout the entire process of research and development of oral dosage forms - Tools and approaches of preformulation investigation, formulation/process design, characterization and scale-up in pharmaceutical sciences and technologies - New developments, challenges, trends, opportunities, intellectual property issues and regulations in solid product development - The first book (ever) that provides comprehensive and in-depth coverage of what's required for developing high quality pharmaceutical products to meet international standards - It covers a broad scope of topics that encompass the entire spectrum of solid dosage form development for the global market, including the most updated science and technologies, practice, applications, regulation, intellectual property protection and new development trends with case studies in every chapter - A strong team of more than 50 well-established authors/co-authors of diverse background, knowledge, skills and experience from industry, academia and regulatory agencies

Food Formulation

Food Formulation
Author: Shivani Pathania
Publisher: John Wiley & Sons
Total Pages: 340
Release: 2021-03-15
Genre: Technology & Engineering
ISBN: 1119614740

Reviews innovative processing techniques and recent developments in food formulation, identification, and utilization of functional ingredients Food Formulation: Novel Ingredients and Processing Techniques is a comprehensive and up-to-date account of novel food ingredients and new processing techniques used in advanced commercial food formulations. This unique volume will help students and industry professionals alike in understanding the current trends, emerging technologies, and their impact on the food formulation techniques. Contributions from leading academic and industrial experts provide readers with informed and relevant insights on using the latest technologies and production processes for new product development and reformulations. The text first describes the basis of a food formulation, including smart protein and starch ingredients, healthy ingredients such as salt and sugar replacers, and interactions within the food components. Emphasizing operational principles, the book reviews state-of-the-art 3D printing technology, encapsulation and a range of emerging technologies including high pressure, pulsed electric field, ultrasound and supercritical fluid extraction. The final chapters discuss recent developments and trends in food formulation, from foods that target allergies and intolerance, to prebiotic and probiotic food formulation designed to improve gut health. A much-needed reference on novel sourcing of food ingredients, processing technologies, and application, this book: Explores new food ingredients as well as impact of processing on ingredient interactions Describes new techniques that improve the flavor and acceptability of functional food ingredients Reviews mathematical tools used for recipe formulation, process control and consumer studies Includes regulations and legislations around tailor-made food products Food Formulation: Novel Ingredients and Processing Techniques is an invaluable resource for students, educators, researchers, food technologists, and professionals, engineers and scientists across the food industry.

Formulation Technology

Formulation Technology
Author: Hans Mollet
Publisher: John Wiley & Sons
Total Pages: 445
Release: 2008-11-21
Genre: Science
ISBN: 3527612939

Many chemical substances or compounds - organic or inorganic, natural or synthetic - are not used in their pure form. In order for the active ingredient to be most effective or to obtain the ideal delivery form for the market, the actual synthesis and purification steps are followed by formulation to give end products that range from powders, agglomerates, and granules to suspensions, emulsions, microemulsions, microcapsules, instant preparations, liposomes, and tablets. Formulation combines colloid and surface chemistry with chemical process engineering; sometimes it consists of a simple mixing operation, sometimes it requires an entire series of rather complicated engineering procedures such as comminution, dispersion, emulsification, agglomeration or drying. This book covers basic physico-chemical theory as well as its applications in the chemical industry for the production of pharmaceuticals, agrochemicals, pigments and dyes, food, detergents, cosmetics and many other products; it also provides chemists and chemical engineers with the necessary practical tools for the understanding of the structure/ activity relationship.

Introduction to Applied Optimization

Introduction to Applied Optimization
Author: Urmila Diwekar
Publisher: Springer Science & Business Media
Total Pages: 342
Release: 2013-03-09
Genre: Mathematics
ISBN: 1475737459

This text presents a multi-disciplined view of optimization, providing students and researchers with a thorough examination of algorithms, methods, and tools from diverse areas of optimization without introducing excessive theoretical detail. This second edition includes additional topics, including global optimization and a real-world case study using important concepts from each chapter. Introduction to Applied Optimization is intended for advanced undergraduate and graduate students and will benefit scientists from diverse areas, including engineers.

PSYCHOLOGICAL SUPPORT BY COGNITIVE BEHAVIORAL THERAPY FOR NEUROFIBROMATOSIS TYPE 1

PSYCHOLOGICAL SUPPORT BY COGNITIVE BEHAVIORAL THERAPY FOR NEUROFIBROMATOSIS TYPE 1
Author: Edenilson Brandl
Publisher: Edenilson Brandl
Total Pages: 1475
Release:
Genre: Psychology
ISBN:

Neurofibromatosis Type 1 (NF1) is a complex genetic disorder that affects various aspects of a person's physical, emotional, and psychological health. As a condition with visible and often life-altering manifestations, NF1 presents unique challenges that go beyond the physical symptoms. The emotional toll, the psychological burden, and the societal pressures faced by those living with NF1 require a holistic and compassionate approach to care. This is where Cognitive Behavioral Therapy (CBT) emerges as a powerful tool for managing the mental health challenges associated with this condition. In this book, "Psychological Support by Cognitive Behavioral Therapy for Neurofibromatosis Type 1," I aim to provide a comprehensive guide that bridges the gap between the medical and psychological aspects of living with NF1. The focus here is on utilizing CBT to address the mental health challenges faced by individuals with NF1 and their families. This book explores the intricacies of how trauma, anxiety, depression, and other mental health issues can manifest in those living with a chronic genetic disorder, and how CBT can be tailored to meet their specific needs. As someone deeply passionate about the intersection of genetics and psychology, I have structured this book to offer both scientific insights and practical therapeutic tools. The first section introduces the biological and genetic foundations of NF1, providing a clear understanding of how genetic mutations can influence both the body and the mind. This is followed by a detailed exploration of CBT techniques, strategies, and tools, designed to help individuals with NF1 cope with the emotional and psychological challenges of their condition. Special attention is given to pain management, identity struggles, and the daily stressors that accompany life with NF1. My hope is that this book will serve as a valuable resource for patients, families, caregivers, and mental health professionals alike. By combining the latest scientific knowledge with practical therapeutic approaches, I believe we can help individuals with NF1 not only manage their symptoms but also improve their overall quality of life. Cognitive Behavioral Therapy provides a structured, evidence-based approach to fostering resilience, building coping skills, and developing healthier patterns of thinking and behavior—essential tools for navigating the complexities of living with Neurofibromatosis Type 1. It is my belief that with the right psychological support, individuals with NF1 can live fulfilling lives despite the challenges they face. This book is dedicated to all those living with Neurofibromatosis Type 1, their loved ones, and the professionals who are committed to improving their mental and emotional well-being.

Pharmaceutics

Pharmaceutics
Author: Alekha Dash
Publisher: Elsevier
Total Pages: 588
Release: 2023-09-13
Genre: Medical
ISBN: 032399797X

Pharmaceutics: Basic Principles and Application to Pharmacy Practice, Second Edition is a valuable textbook covering the role and application of pharmaceutics within pharmacy practice. This updated resource is geared toward meeting and incorporating the current curricular guidelines on pharmaceutics and laboratory skills mandated by the American Council for Pharmacy Education. It includes a number of student-friendly features, including chapter objectives and summaries, practical examples, case studies, numerous images and key-concept text boxes. Two new chapters are included, as well as a new end of chapter section covering "critical reflections and practice applications". Divided into three sections – Physical Principles and Properties of Pharmaceutics; Practical Aspects of Pharmaceutics; and Biological Applications of Pharmaceutics – this new edition covers all aspects of pharmaceutics and providing a single and compelling source for students. - Facilitates an integrated and extensive coverage of the study of pharmaceutics due to the clear and engaging language used by the authors - Includes chapter objectives and summaries to illustrate and reinforce key ideas - Meets curricular guidelines for pharmaceutics and laboratory skills mandated by the Accreditation Council for Pharmacy Education (ACPE) - Includes new practice questions, answers, and case studies for experiential learning