Basement Membranes And Cell Movement
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| Author | : Jamie Davies |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 255 |
| Release | : 2007-03-20 |
| Genre | : Science |
| ISBN | : 0387308733 |
Branching morphogenesis, the creation of branched structures in the body, is a key feature of animal and plant development. This book brings together, for the first time, expert researchers working on a variety of branching systems to present a state-of-the-art view of the mechanisms that control branching morphogenesis. Systems considered range from single cells, to blood vessel and drainage duct systems to entire body plans, and approaches range from observation through experiment to detailed biophysical modelling. The result is an integrated overview of branching.
| Author | : |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2002 |
| Genre | : Cells |
| ISBN | : 9780815332183 |
| Author | : Ruth Porter |
| Publisher | : John Wiley & Sons |
| Total Pages | : 192 |
| Release | : 2009-09-14 |
| Genre | : Science |
| ISBN | : 0470718595 |
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
| Author | : E.D. Hay |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 478 |
| Release | : 2013-11-11 |
| Genre | : Science |
| ISBN | : 1461537703 |
In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has enor mously increased. Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell biology societies. Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won dered how best to incorporate the new material. For example, we deliberated over the inclusion of chapters on molecular genetics. We decided that with judicious editing we could present the recent findings in molecular biology within the same cell biology framework that was used for the first edition, using three broad headings: what is extracellular matrix, how is it made, and what does it do for cells? Maintaining control over the review of literature on the subject of ECM was not always an easy task, but we felt it was essential to production of a highly readable volume, one compact enough to serve the the student as an introduction and the investigator as a quick update on graduate the important recent discoveries. The first edition of this volume enjoyed con hope the reader finds this edition equally useful. siderable success; we D. Hay Elizabeth vii Contents Introductory Remarks 1 Elizabeth D. Hay PART I. WHAT IS EXTRACELLULAR MATRIX? Chapter 1 Collagen T. F. Linsenmayer 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. The Collagen Molecule . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 2. 1. Triple-Helical Domain(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
| Author | : Joshua Scallan |
| Publisher | : Morgan & Claypool Publishers |
| Total Pages | : 86 |
| Release | : 2010 |
| Genre | : Science |
| ISBN | : 1615040668 |
The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the extracellular matrix and lymphatics. In addition to its role in the regulation of vascular volume, transcapillary fluid filtration also allows for continuous turnover of water bathing tissue cells, providing the medium for diffusional flux of oxygen and nutrients required for cellular metabolism and removal of metabolic byproducts. Transendothelial volume flow has also been shown to influence vascular smooth muscle tone in arterioles, hydraulic conductivity in capillaries, and neutrophil transmigration across postcapillary venules, while the flow of this filtrate through the interstitial spaces functions to modify the activities of parenchymal, resident tissue, and metastasizing tumor cells. Likewise, the flow of lymph, which is driven by capillary filtration, is important for the transport of immune and tumor cells, antigen delivery to lymph nodes, and for return of filtered fluid and extravasated proteins to the blood. Given this background, the aims of this treatise are to summarize our current understanding of the factors involved in the regulation of transcapillary fluid movement, how fluid movements across the endothelial barrier and through the interstitium and lymphatic vessels influence cell function and behavior, and the pathophysiology of edema formation. Table of Contents: Fluid Movement Across the Endothelial Barrier / The Interstitium / The Lymphatic Vasculature / Pathophysiology of Edema Formation
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 504 |
| Release | : 2018-05-28 |
| Genre | : Science |
| ISBN | : 0128098031 |
Extracellular Matrix and Egg Coats, Volume 130, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on The Human Egg's Zona Pellucida, the Structure of Zona Pellucida Module Proteins, The Fish Egg's Zona Pellucidam The Chicken Egg's Zona Pellucidam The Marsupial Egg's Zona Pellucida, the Evolution of Zona Pellucida Proteins, The Mouse Egg's Zona Pellucida, Aspects of ECM, ECM and Morphogenesis, Collagen fibril assembly and function, The Ear's Tectorial Membrane, ECM and Cell Fate, and the Aspects of ECM. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Current Topics in Developmental Biology series - Updated release includes the latest information on the Extracellular Matrix in Development
| Author | : Robert Mecham |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 429 |
| Release | : 2011-02-16 |
| Genre | : Science |
| ISBN | : 3642165559 |
Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
| Author | : Fred W. Keeley |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 297 |
| Release | : 2013-03-15 |
| Genre | : Science |
| ISBN | : 3642360025 |
The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed.
| Author | : James S. Lowe |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 439 |
| Release | : 2018-12-26 |
| Genre | : Medical |
| ISBN | : 0323612806 |
Easy to read, well organized, and focused on high-yield content, Human Histology, 5th Edition, features concise, up-to-date coverage of the core knowledge in this complex field. Ideal for students in all areas of health care, this revised edition is aligned with recent developments in integrated and problem-based learning, providing rapid access to relevant, practical knowledge in histology. It provides students with opportunities to make important connections between histological knowledge, cell biology, anatomy, clinical understanding, and assessment. - Features an easy-to-navigate, full-colour layout that includes summary headings, readable text, quick-reference tables, and key facts – all highlighted by nearly 900 clear illustrations, photos, and graphics throughout. - Covers the latest concepts and advances in histology including developments in the primary cilium, the nuclear pore, extracellular matrix components, dendritic spines, subsets of astrocytes, haematopoiesis, classification of cells in the immune system, macrophage subsets, and much more. - Includes NEW self-assessment questions. - Provides just the right amount of detail for maximum readability and retention. - Highlights key laboratory, clinical, and high-level scientific material in boxes. - Presents advanced concepts such as the molecular and functional relevance of histological features. - Provides review material in the book and online, self-assessment questions plus 180 additional review questions online. - Evolve Instructor Resources, including a downloadable image and test bank, are available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com
| Author | : Anders Rehfeld |
| Publisher | : Springer |
| Total Pages | : 670 |
| Release | : 2017-09-07 |
| Genre | : Medical |
| ISBN | : 3319418734 |
This book has been designed to help medical students succeed with their histology classes, while using less time on studying the curriculum. The book can both be used on its own or as a supplement to the classical full-curriculum textbooks normally used by the students for their histology classes. Covering the same curriculum as the classical textbooks, from basic tissue histology to the histology of specific organs, this book is formatted and organized in a much simpler and intuitive way. Almost all text is formatted in bullets or put into structured tables. This makes it quick and easy to digest, helping the student get a good overview of the curriculum. It is easy to locate specific information in the text, such as the size of cellular structures etc. Additionally, each chapter includes simplified illustrations of various histological features. The aim of the book is to be used to quickly brush up on the curriculum, e.g. before a class or an exam. Additionally, the book includes guides to distinguish between the different histological tissues and organs that can be presented to students microscopically, e.g. during a histology spot test. This guide lists the specific characteristics of the different histological specimens and also describes how to distinguish a specimen from other similar specimens. For each histological specimen, a simplified drawing and a photomicrograph of the specimen, is presented to help the student recognize the important characteristics in the microscope. Lastly, the book contains multiple “memo boxes” in which parts of the curriculum are presented as easy-to-remember mnemonics.
