In this issue of Hand Clinics, guest editors Drs. Mitchell A. Pet and Charles A. Daly bring their considerable expertise to the topic of Avascular Necrosis of the Carpal Bones: Etiologies and Treatments. Avascular necrosis of the carpal bones is a key cause of wrist pain and limitations to motion, as well as strength limitations. Oftentimes, these conditions devolve into arthritis. AVN (osteonecrosis) in the carpus is death of the surrounding bone marrow tissues; Kienböck disease in particular is osteonecrosis of the lunate. In this issue, top experts provide a state-of-the-art review of AVN of the carpal tissues, with a particular emphasis on diagnosis and treatment. Contains 12 practice-oriented topics including an algorithmic approach to the treatment of Kienbock’s disease; osteotomies, core decompression, and denervation for the treatment of Kienbock’s disease; vascularized bone flaps for the treatment of Kienbock’s disease; arthroscopic interventions for Kienbock’s disease; Preiser’s disease; and more. Provides in-depth clinical reviews on avascular necrosis of the carpal bones, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.