The process of globalization based on major forms of entertainment consumption has promoted the interest of enlarged social actors toward cultural experiencing. Disseminated by social media, new forms of information and knowledge about exotic tourism destinations have endorsed an increasing interest in forms of cultural tourism. This cultural tourism turnout results from a significant change in the traveler’s demands and behaviors and has led to a new and renovated interest in cultural heritage that must be studied further. The Handbook of Research on Cultural Tourism and Sustainability explores theoretical concepts related to cultural tourism and cultural routes and provides original viewpoints and empirical research with case studies and best practices for the future of cultural tourism. Covering a range of topics such as creative tourism and sustainable tourism, this major reference work is ideal for academicians, practitioners, professionals, policymakers, government officials, instructors, and students.