Atmospheric Pressure Plasma Decontamination Sterilization Chamber
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| Release | : 2001 |
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An atmospheric-pressure plasma decontamination/sterilization chamber is described. The apparatus is useful for decontaminating sensitive equipment and materials, such as electronics, optics and national treasures, which have been contaminated with chemical and/or biological warfare agents, such as anthrax, mustard blistering agent, VX nerve gas, and the like. There is currently no acceptable procedure for decontaminating such equipment. The apparatus may also be used for sterilization in the medical and food industries. Items to be decontaminated or sterilized are supported inside the chamber. Reactive gases containing atomic and metastable oxygen species are generated by an atmospheric-pressure plasma discharge in a He/O.sub. 2 mixture and directed into the region of these items resulting in chemical reaction between the reactive species and organic substances. This reaction typically kills and/or neutralizes the contamination without damaging most equipment and materials. The plasma gases are recirculated through a closed-loop system to minimize the loss of helium and the possibility of escape of aerosolized harmful substances.
| Author | : Spencer P Kuo |
| Publisher | : World Scientific |
| Total Pages | : 210 |
| Release | : 2019-01-25 |
| Genre | : Science |
| ISBN | : 9813279869 |
Cold atmospheric plasma (CAP) generators have been actively developed as a new device for medical treatment. The applications of plasma treatment include 1) disinfection, sterilization, and decontamination, which inactivates or kills bacteria, fungi, viruses and spores; 2) bleeding control, which coagulates blood swiftly; 3) wound healing, which shortens the healing period and benefits the regeneration of the epithelization of tissue to avoid scar formation; etc.Biomedical applications of CAPs are explored via either in-vitro assays, or in-vivo tests using pigs as animal models; tests include sterilization of oral pathogens and biofilm, decontamination of biological warfare agent, blood clotting and rapid control of active life-threatening hemorrhage, and post-operative observation of wound healing after plasma treatment. The conventional approaches in each application are first introduced, then the advantages of plasma treatments are discussed and demonstrated by the test results. The mechanisms of CAPs' biocidal effect, blood clotting effect, and wound healing effect are presented and discussed.
| Author | : Zdenko Machala |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 479 |
| Release | : 2012-02-05 |
| Genre | : Science |
| ISBN | : 9400728514 |
Non-thermal (cold) plasmas at atmospheric pressure have recently found many breakthrough applications in biology, medicine, and food security. Plasmas can efficiently kill bacteria, yeasts, moulds, spores, biofilms and other hazardous microorganisms, including potential bio-terrorism agents. They can be employed for bio-decontamination and sterilization of surfaces, medical instruments, water, air, food, even of living tissues without causing their damage. Direct or indirect plasma interaction with living cells of microorganisms or even humans enables novel bio-medical applications, e.g. treatment of skin diseases and ulcers. Plasma-enhanced blood coagulation coupled with its antiseptic properties proved success in wound healing and opens new possibilities in surgery, emergency medicine and military applications. Plasma treatment allows cell manipulations, their removal and targeted transfer into the injured area, which can accelerate wound healing. Plasma induced apoptosis (programmed cell death) of tumor cells brings forth a great potential for cancer treatment. Besides, plasma enables painless treatment of dental caries, root canal disinfection, and other dentistry applications. This book is a selection of reviewed manuscripts issuing from the NATO Advanced Research Workshop Plasma for bio-decontamination, medicine and food security held in Jasná, Slovakia, on 15-18 March 2011. It provides a comprehensive overview of the current knowledge and research activities focused at the plasma applications in areas such as bio-decontamination, water chemistry, effects on cells; biofilm inactivation, UV sterilization, and medicine, especially tissue treatment and wound healing, as well as dentistry and food security.
| Author | : Selçuk Güçeri |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 306 |
| Release | : 2011-10-12 |
| Genre | : Science |
| ISBN | : 1402084390 |
Plasma decontamination is a rapidly expanding area of modern science and engineering. An increasing number of engineers are using plasma methods for decontamination of chemical and biological agents. Plasma decontamination is effectively applied today to clean and sterilize different surfaces, high volume air and water streams, industrial exhausts, and even living tissue of animals and humans. This book provides a fundamental introduction to virtually all aspects of modern plasma decontamination, as well as the most recent technological achievements in the area. The book is segmented into four specific sections of modern plasma decontamination: (1) plasma bio-decontamination, including disinfection and sterilization of surfaces, water and air streams; (2) plasma decontamination of chemical agents, including cleaning of air, water, and industrial exhaust gases from different pollutants and especially volatile organic compounds VOC; (3) plasma treatment of living tissue, including different subjects of plasma medicine from skin sterilization to tissue engineering; (4) major electric discharges applied for the plasma-assisted decontamination of chemical and biological agents.
| Author | : Alexander Fridman |
| Publisher | : CRC Press |
| Total Pages | : 888 |
| Release | : 2004-04-15 |
| Genre | : Science |
| ISBN | : 9781560328483 |
Plasma engineering is a rapidly expanding area of science and technology with increasing numbers of engineers using plasma processes over a wide range of applications. An essential tool for understanding this dynamic field, Plasma Physics and Engineering provides a clear, fundamental introduction to virtually all aspects of modern plasma science and technology, including plasma chemistry and engineering, combustion, chemical physics, lasers, electronics, methods of material treatment, fuel conversion, and environmental control. The book contains an extensive database on plasma kinetics and thermodynamics, many helpful numerical formulas for practical calculations, and an array of problems and concept questions.
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| Release | : 2004 |
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Steady-state atmospheric pressure nonthermal plasmas can splendidly debilitate bacteria in liquids, gases and on surfaces, as well as can disintegrate hazardous chemicals. The nonthermal gas discharge at atmospheric pressure, such as resistive barrier discharge is investigated for low temperature sterilization purposes. In specific, exploring and understanding the hidden secrets of the plasma sterilization mechanisms and the intensification of the main microbial reduction pathways are the objectives of the research. A dual-mode steady-state atmospheric pressure resistive barrier ionized gas (plasma) generator has been designed and developed to meet the environmental health and federally mandated safety standards. Electrical, chemical, optical, and biological studies are carried out on the Steady-State, Atmospheric Pressure Resistive Barrier Discharge, with the intent of identifying the chemically and biologically active species produced. The goals of the research work are to prepare an effective, inexpensive plasma sterilization process and to identify and escalate the main contributing active species responsible for plasma sterilization. The effectiveness of ionized gases produced by the resistive barrier plasma discharge on sterilizing bacteria has been analyzed. Bacteria at a dilution that achieved a countable number of colonies were exposed or not exposed to ionized gases for various periods of time and monitored to determine the effects of ionized gas treatment.
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| Total Pages | : 42 |
| Release | : 1999 |
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Our Phase I effort was meant to demonstrate that an effective technology for rapid surface sterilization of biological contaminants and neutralization of chemical warfare agents could be developed based on the application of an atmospheric pressure plasma. We used both a DC corona and dielectric barrier discharge for the sterilization tests which were conducted on a variety of substrates including metals and chemically resistant fabrics. Medically accepted biological indicator spores (Bacillus subtilis var niger and Bacillus stearothermophilus) were used to determine the effectiveness of the plasma discharge. The chemical neutralization tests were conducted using a DC corona discharge on a metal substrate contaminated with either diisopropylmethyl phosphonate or dimethylmethyl phosphonate. These simulants are of similar chemical structure to classes of chemical warfare agents like GB and Sarin. Results include decomposition of the chemical agent simulants with decomposition by-products including water, acetic acid and gases like CO2; complete sterilization in 15 minutes of some substrates contaminated with up to 105 spores over about a 1 cm2 and the concentration of the model pathogens and the surface characteristics of the contaminated substrate affects the sterilization results. A rough surface with defects is difficult to completely sterilize on short time scales
| Author | : NN Misra |
| Publisher | : Academic Press |
| Total Pages | : 382 |
| Release | : 2016-07-15 |
| Genre | : Technology & Engineering |
| ISBN | : 012801489X |
Cold Plasma in Food and Agriculture: Fundamentals and Applications is an essential reference offering a broad perspective on a new, exciting, and growing field for the food industry. Written for researchers, industry personnel, and students interested in nonthermal food technology, this reference will lay the groundwork of plasma physics, chemistry, and technology, and their biological applications. Food scientists and food engineers interested in understanding the theory and application of nonthermal plasma for food will find this book valuable because it provides a roadmap for future developments in this emerging field. This reference is also useful for biologists, chemists, and physicists who wish to understand the fundamentals of plasma physics, chemistry, and technology and their biological interactions through applying novel plasma sources to food and other sensitive biomaterials. Examines the topic of cold plasma technology for food applications Demonstrates state-of-the-art developments in plasma technology and potential solutions to improve food safety and quality Presents a solid introduction for readers on the topics of plasma physics and chemistry that are required to understand biological applications for foods Serves as a roadmap for future developments for food scientists, food engineers, and biologists, chemists, and physicists working in this emerging field
| Author | : Yusuf Tutar |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 152 |
| Release | : 2018-05-16 |
| Genre | : Medical |
| ISBN | : 1789231124 |
Plasma can be defined as the extracellular matrix of blood cells. Plasma components, their role in human health risk evaluation, and their functional and clinical analyses are covered in this book. Furthermore, physical plasma-ionized gas is one of the four fundamental states of matter. This homonym has begun to emerge because it can interact with living systems. The physical plasma biomedical applications are reviewed in drug delivery and wound healing medical applications. This approach revolutionizes the therapeutic approaches in medicine and may open up new concepts and clinical applications. The book is an essential source for researchers in the field and provides a platform for different professions.
| Author | : Prasun Kumar |
| Publisher | : Springer Nature |
| Total Pages | : 694 |
| Release | : 2021-07-20 |
| Genre | : Medical |
| ISBN | : 9811626774 |
This book presents the latest knowledge on both the physiological and the microbiological aspects of wound healing. Fresh insights into the process of cutaneous wound healing are described, which involves tissue regeneration and repair processes consisting of a sequence of molecular and cellular events. The management of infected wounds is then discussed in detail, covering the roles of traditional medicine practices, novel anti-infective formulations, non-antibiotic approaches, and probiotic bacteria. A section devoted to the interdisciplinary approach to wound care addresses topics including in vitro and in vivo research models, the development of advanced wound dressings, tissue engineering, and the potential applications of bioscaffolds. The authors are all leading researchers in the field. This book is an attempt to showcase current research status and future directions in the area of wound-healing research, which must be of interest to a large group of readers and researchers interested in this field.
