Background and Aims: Behavioral and psychological symptoms of dementia (BPSD) represent a heterogeneous group of non-cognitive symptoms and behaviors occurring in subjects with dementia. They constitute a major component of the dementia syndrome. This study aims to evaluate the BPSD and to assess their management.Methods:A retrospective study, involving 45 diagnosed patients with dementia (DSM 5) and followed in the psychiatry department of Hedi Chaker University Hospital in Sfax (Tunisia) between January 2016 and September 2018. Sociodemographic, clinical and therapeutic data was collected from their medical records.Results:The mean age was 75.6 years (range 52-95 years), with a sex-ratio of 0.7. The different types of dementia were Alzheimeru2019s disease (77.8%), vascular dementia (20%) and fronto-temporal dementia (2.2%). Nearly two-thirds of patients (75.6%) had at least one BPSD, 26.6% had u2265 4 symptoms. Most frequent BPSD were delirium (55.6%), agitation (53%), hallucinations (51%), aggressiveness (38%). Mood disorders, apathy, anxiety and disinhibition were least frequent. Nearly one-third (31%) of patients were on cholinesterase inhibitors, 56% were on atypical antipsychotics, 20% were on antidepressant and 24.4% were on benzodiazepine. The majority of cases (71.1%) were on polytherapy with psychotropic drugs. Adverse drug reaction monitoring has been determined only for 39.5% of patients.Conclusions:BPSD occur on as dementia evolves, regardless of the dementia type. Their care is not always suited to recommendations. Improving our recognition and management of BPSD is considered necessary because it can have a positive impact on the quality of life of our patients and potentially delay the transition from home to institutional care.