Assessing Health-related Quality of Life for Patients with Parkinson's Disease and Atypical Parkinsonian Disorders

Assessing Health-related Quality of Life for Patients with Parkinson's Disease and Atypical Parkinsonian Disorders
Author: Kindra Kaye Noe
Publisher:
Total Pages: 106
Release: 2009
Genre: Parkinson's disease
ISBN:

Advances in the treatment of Parkinson's disease (PD) and atypical Parkinsonian disorders (APD) have made it easier for physicians to treat the physical aspects of these diseases. However, it is becoming increasingly evident that more than just the physical symptoms need to be treated in order to improve overall quality of life (QoL) among PD and APD patients. This study assesses the key factors that influence health-related QoL for both PD and APD patients and compares across the two disease groups as well as among the APD group. Three hundred and fifty three patients were used in this study and diagnosed with having PD (187), PSP (50), MSA (65), DLB (34), or CBD (17). Each patient completed the short form-12 (SF-12), Beck's Depression Inventory (BDI), Unified Parkinson's Disease Rating Scale (UPDRS), Mini-Mental State Examination (MMSE), Schwab and England (SE) and the Hoehn and Yahr rating scale (HY) which measured for QoL, depression, mood, behavior, motor functioning, activities of daily living, cognitive function and disease severity. We also looked at age and gender identification. After analyzing the results, APD patients were found to have overall lower health-related QoL than PD patients in earlier age groups when comparing SF-12 PCS scores. MCS scores between PD and APD were not significantly different. In addition, no significant differences were found between SF-12 scores when comparing PSP, MSA, CBD and DLB. Depression was found to be the main determinant of health-related QoL among all disease groups, and was a stronger predictor of QoL for PD than APD. Mood, behavior and mentation were predictors of QoL for PD and DLB. Motor functioning, age and gender were significant determinants of QoL only for PD, while disease severity was a determining factor for MSA and CBD patients. In addition, activities of daily living was a predictor of QoL for PD, DLB, and PSP. This study shows that various factors affect health-related QoL differently among different disease groups and should be taken into consideration by physicians in order to provide the best medical care possible.

Parkinson's Disease and Quality of Life

Parkinson's Disease and Quality of Life
Author: Lucien Cote
Publisher: Routledge
Total Pages: 210
Release: 2014-01-21
Genre: Medical
ISBN: 131782640X

Learn to handle the problems that Parkinson's patients face Through Parkinson's Disease and Quality of Life, you will discover common problem areas seen in patients with Parkinson's disease. This book explores problems that interfere with functional independence of patients and gives examples of occupational therapy intervention and treatment techniques. Parkinson's Disease and Quality of Life boldly deals with many seldom talked about real-life issues facing people with Parkinson's disease, including continued sexual intimacy and urinary incontinence. Although these issues may not be curable, this book provides you with effective treatments through data and case studies. Parkinson's Disease and Quality of Life offers caregivers a step-by-step plan to get organized. It includes a plan to put together a workbook of all relevant information, as well as tips on how to safeguard every room for a Parkinson's disease patient. This book helps remind you that the families of the patient must not be forgotten and that they can get the help they need through support groups, community resources, and from professional staffing such as nurses and aides. Parkinson's Disease and Quality of Life will assist you in helping your patients by: using music therapy to help calm patients realizing the legal impact of Parkinson's disease by discussing living wills, health care proxies, durable power of attorney, and revocable and irrevocable trusts with your clients discovering that cognitive changes, dementia, and depression can complicate the treatment of the disease and be more disabling than the loss of motor function exploring the nursing home as a viable options for clients as well as their families Parkinson's Disease and Quality of Life also brings to light the important subject of knowing the patients insurance policies and working out contingency plans, like living wills, before they are needed. This book gives you much-needed information on accessing benefits for Parkinson's patients, including medicare, social security, Veteran's benefits, and much more. Parkinson's Disease and Quality of Life is full of methods and ideas to improve the lives of the Parkinson's patient as well as their families.

Guide to Assessment Scales in Parkinson’s Disease

Guide to Assessment Scales in Parkinson’s Disease
Author: Pablo Martinez-Martin
Publisher: Springer
Total Pages: 96
Release: 2014-10-16
Genre: Medical
ISBN: 1907673881

This Guide assesses the key clinimetric attributes in the assessment of Parkinson's Disease (PD), with the intention to offer rapid and pragmatic information on the most relevant scales used in PD. Parkinson’s disease affects approximately 4 million people globally and is most commonly seen in people over the age of 50. The disease is a progressive disorder of the nervous system, and presents a number of movement and cognitive symptoms, thereby greatly affecting a patients quality of life. The use of scales for assessment in neurological disorders such as PD arises from the need to quantify disorders and states (such constructs as disability, symptoms, quality of life). Assessment scales are often categorised into two categories: generic (i.e. those scales usable in any health condition), and specific (i.e. scales developed for exclusive use in PD). They can have a variety of components: single-item and multi-item or composite scale; unidimensional and multidimensional; and as disease-centered and patient-centered measures. The creation and validation of scales is complex, with scales undergoing numerous studies to assess criteria such as acceptability, reliability, and responsiveness. In the process of validation of a scale the following attributes should be tested to ascertain whether a scale is an effective instrument of measurement.

Etiology of Parkinson's Disease

Etiology of Parkinson's Disease
Author: Jonas H. Ellenberg
Publisher: CRC Press
Total Pages: 600
Release: 1995-03-01
Genre: Medical
ISBN: 9780824788230

This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.

Guide to Assessment Scales in Parkinson’s Disease

Guide to Assessment Scales in Parkinson’s Disease
Author: Pablo Martinez-Martin
Publisher: Springer
Total Pages: 100
Release: 2013-12-11
Genre: Medical
ISBN: 9783319040240

Parkinson’s disease (PD) affects approximately 4 million people globally and is most commonly seen in people over the age of 50. The disease is a progressive disorder of the nervous system, and presents a number of movement and cognitive symptoms, thereby greatly affecting a patients quality of life. The use of scales for assessment in neurological disorders such as PD arises from the need to quantify disorders and states (such constructs as disability, symptoms, quality of life). Assessment scales are often categorised into two categories: generic (ie. those scales usable in any health condition), and specific (ie. scales developed for exclusive use in PD). They can have a variety of components: single-item and multi-item or composite scale; unidimensional and multidimensional; and as disease-centered and patient-centered measures. The creation and validation of scales is complex, with scales undergoing numerous studies to assess criteria such as acceptability, reliability, and responsiveness. In the process of validation of a scale the following attributes should be tested to ascertain whether a scale is an effective instrument of measurement. This Guide assesses the key clinimetric attributes in the assessment of PD, with the intention to offer rapid and pragmatic information on the most relevant scales used in PD.

Non-Motor Symptoms of Parkinson's Disease

Non-Motor Symptoms of Parkinson's Disease
Author: K. Ray Chaudhuri
Publisher: Oxford University Press, USA
Total Pages: 517
Release: 2014
Genre: Medical
ISBN: 0199684243

Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus on the NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians. The NMS of PD have a significant impact on patient quality of life and mortality and include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require research into novel (non-dopaminergic) drug therapies for the future. Edited by members of the UK Parkinson's Disease Non-Motor Group (PD-NMG) and with contributions from international experts, this new edition summarizes the current understanding of NMS symptoms in Parkinson's disease and points the way towards future research.

Atypical Parkinsonian Disorders

Atypical Parkinsonian Disorders
Author: Irene Litvan
Publisher: Springer Science & Business Media
Total Pages: 515
Release: 2007-10-27
Genre: Medical
ISBN: 159259834X

A comprehensive review of what is known not only about the cause and treatment of atypical parksonian disorders, but also the issues that clinicians, researchers, patients, and caregivers face in dealing with them. The authors cover the basic science (history, epidemiology, genetics, pathology, nosology, computer modeling, and animal models), detailed clinical and laboratory assessments, and available diagnostic tools, including neuropsychiatric, neurologic, neuropsychologic, speech, electrophysiologic, and imaging evaluations. Current and future therapeutic approaches are also detailed, along with extensive discussions about future research directions.

Autonomic Dysfunction in Parkinson's Disease

Autonomic Dysfunction in Parkinson's Disease
Author: Cristian Falup-Pecurariu
Publisher: Academic Press
Total Pages: 316
Release: 2021-09-28
Genre: Technology & Engineering
ISBN: 0323851231

Autonomic dysfunction is one of the most prevalent non-motor symptoms that occurs in Parkinson's disease. Autonomic Dysfunction in Parkinson's Disease provides up to date information on this important topic, which affects quality of life of these patients. This include a large number of domains: orthostatic hypotension, excessive sweating, dry eyes, constipation, weight loss, increased sensitivity to heat and cold, sexual dysfunction. - Provides comprehensive reviews on different topics of autonomic dysfunction in Parkinson's disease - Each chapter covers a specific autonomic symptom: classification, assessment, treatment - Presents the newest information on each autonomic symptom in Parkinson's disease