Aptasensors For Point Of Care Diagnostics
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| Author | : Arpana Parihar |
| Publisher | : CRC Press |
| Total Pages | : 375 |
| Release | : 2023-12-18 |
| Genre | : Technology & Engineering |
| ISBN | : 1003829503 |
The design and fabrication of aptamer-based biosensors for point-of-care testing of disease diagnostic and prognostic is an upthrust and interdisciplinary area of research. This book covers the design and development of novel cost-effective aptamer-based biosensors for disease diagnostic and prognostic including an understanding of health care management in terms of timely updates of disease situations in a particular geographical area. It also discusses the scaling up and market trend of aptamer-based devices for extension of research from lab to market, and end users. Features: Explains the design and fabrication of aptasensors-based diagnostic devices. Includes novel approaches and comprehensive technology overview for diagnosis management towards early-stage detection of various biomarkers associated with several health conditions. Demonstrates possible benefits of combined diagnostics and therapeutic possibilities using aptamer-based point-of-care technologies devices. Discusses emerging implications and recent advances of biosensing platforms for designing and developing aptamer-based point-of-care testing (POCT) devices. Explores aptamer-based approach to develop advanced platforms for medical applications and open arena for state-of-the-art future research. This book is aimed at researchers and graduate students in biomedical engineering, diagnostics, nanobiotechnology, and materials science.
| Author | : Arpana Parihar |
| Publisher | : IOP Publishing Limited |
| Total Pages | : 0 |
| Release | : 2023-10-16 |
| Genre | : Medical |
| ISBN | : 9780750350105 |
This book will demonstrate the current advancement in the field of point-of-care aptasensors-based diagnostic devices, and their working principles, with a historical overview of their utility along with future developments
| Author | : Pankaj Suman |
| Publisher | : Springer Nature |
| Total Pages | : 245 |
| Release | : 2020-10-12 |
| Genre | : Medical |
| ISBN | : 981155823X |
This book presents the timeline of immunodiagnostics evolution, including advancements in immunological/nucleic acid probes, assay design, labelling techniques, and devices for signal transduction and acquisition. In the past few years, enzyme and nanocatalyst-based immune assays have undergone numerous modifications to enhance their sensitivity and potential for automation. Further, to reduce production costs and the use of laboratory animals, engineering small antibodies and nucleic acid probes (aptamers) has become increasingly popular in the development of novel and powerful bioassays. In light of the notable advancements in immunodiagnostics, this book highlights the combined efforts of clinicians, biotechnologists, material scientists, nanotechnologists and basic scientists in a coherent and highly structured way. The book takes readers on the journey of immunodiagnostic technologies, from their introduction to the present.
| Author | : Raju Khan |
| Publisher | : Academic Press |
| Total Pages | : 439 |
| Release | : 2021-08-25 |
| Genre | : Technology & Engineering |
| ISBN | : 0128236515 |
Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient’s life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems. Covers design and development of advanced platforms for rapid diagnosis of cancerous biomarkers Takes a multidisciplinary approach to sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications Offers an insight into how to develop cost-effective diagnostics for early detection of cancer
| Author | : Raju Khan |
| Publisher | : CRC Press |
| Total Pages | : 547 |
| Release | : 2024-10-04 |
| Genre | : Technology & Engineering |
| ISBN | : 1040118607 |
This reference book provides updated knowledge on fundamentals and applications of aptasensors in food science. It discusses aptamer selection strategies including Systematic Evolution of Ligands through EXponential enrichment (SELEX), Capture SELEX, Cell SELEX, and GO SELEX strategies for aptasensor design involving well-studied and newly emerged nanomaterials, food analysis focusing on its safety, aptasensing techniques relevant to detection of food pathogens, pesticides, veterinary drug residues, toxins, heavy metals, allergens, and future perspectives of aptamers in food science and technology. The book focuses on recent developments in aptasensors and their use in detection of contaminants in food. The book is an excellent resource for R&D organizations dedicated to the development of biosensors in general and aptasensors in particular for the detection of environmental contaminants in the food supply chain. Also, the contents of the book will be useful to researchers, postgraduate students, analytical chemists, food scientists, and regulatory authorities.
| Author | : Yiyang Dong |
| Publisher | : Springer Nature |
| Total Pages | : 470 |
| Release | : 2021-03-25 |
| Genre | : Science |
| ISBN | : 9813348380 |
This book outlines comprehensively the main medical uses of aptamers, from diagnosis to therapeutics in fourteen chapters. Pioneering topics covered include aptamer pharmaceuticals, aptamers for malign tumors, aptamers for personalized therapeutics and aptamers for point-of-care testing. The book offers an essential guide for medical scientists interested in developing aptamer-based schemes for better theranostics. It is therefore of interest for not only academic researchers, but also practitioners and medical researchers in various fields of medical science, medical research and bio-analytical chemistry.
| Author | : Luis Rodrigo |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 236 |
| Release | : 2020-09-30 |
| Genre | : Medical |
| ISBN | : 1839625236 |
Gram-negative Escherichia coli (E. coli) bacteria are the most numerous commensal aerobic germs located in the human colon. Diarrhea caused by E. coli pathogenic strains is a major cause of death in developing countries, especially the sub-Saharan and South Asian areas. Some strains cause diarrhea, and all of them may produce an infectious disease. This book includes ten chapters covering the main aspects of infections related to E. coli, their pathogenic mechanisms, treatments, and resistance to diverse antibiotics.
| Author | : Dr. Inamuddin |
| Publisher | : Elsevier |
| Total Pages | : 432 |
| Release | : 2019-06-15 |
| Genre | : Technology & Engineering |
| ISBN | : 0128165227 |
Advanced Biosensors for Health Care Applications highlights the different types of prognostic and diagnostic biomarkers associated with cancer, diabetes, Alzheimer's disease, brain and retinal diseases, cardiovascular diseases, bacterial infections, as well as various types of electrochemical biosensor techniques used for early detection of the potential biomarkers of these diseases. Many advanced nanomaterials have attracted intense interests with their unique optical and electrical properties, high stability, and good biocompatibility. Based on these properties, advanced nanoparticles have been used as biomolecular carriers, signal producers, and signal amplifiers in biosensor design. Recent studies reported that there are several diagnostic methods available, but the major issue is the sensitivity and selectivity of these approaches. This book outlines the need of novel strategies for developing new systems to retrieve health information of patients in real time. It explores the potential of nano-multidisciplinary science in the design and development of smart sensing technology using micro-nanoelectrodes, novel sensing materials, integration with MEMS, miniaturized transduction systems, novel sensing strategy, that is, FET, CMOS, System-on-a-Chip (SoC), Diagnostic-on-a-Chip (DoC), and Lab-on-a-Chip (LOC), for diagnostics and personalized health-care monitoring. It is a useful handbook for specialists in biotechnology and biochemical engineering. Describes advanced nanomaterials for biosensor applications Relates the properties of available nanomaterials to specific biomarkers applications Includes diagnosis and electrochemical studies based on biosensors Explores the potential of nano-multidisciplinary science to design and develop smart sensing technologies Describes novel strategies for developing a new class of assay systems to retrieve the desired health information
| Author | : Pranjal Chandra |
| Publisher | : Springer |
| Total Pages | : 403 |
| Release | : 2017-12-30 |
| Genre | : Medical |
| ISBN | : 981104726X |
This book presents recent research on cancer detection methods based on nanobiosensors, which offer ultrasensitive point-of-care diagnosis. Several methods for diagnosing cancer have been discovered and many more are currently being developed. Conventional clinical approaches to detecting cancers are based on a biopsy followed by histopathology, or on the use of biomarkers (protein levels or nucleic acid content). Biopsy is the most widely used technique; however, it is an invasive technique and is not always applicable. Furthermore, biomarker-based detection cannot be relied on when the biomarkers are present in an extremely low concentration in the body fluids and in malignant tissues. Thus, in recent years highly sensitive and robust new cancer diagnosis techniques have been developed for clinical application, and may offer an alternative strategy for cancer diagnosis. As such, this book gathers the latest point-of-care cancer diagnostic methods and protocols based on biomedical sensors, microfluidics, and integrated systems engineering. It also discusses recent developments and diagnostics tests that can be conducted outside the laboratory in remote areas. These technologies include electrochemical sensors, paper-based microfluidics, and other kit-based diagnostic methods that can be adapted to bring cancer detection and diagnostics to more remote settings around the globe. Overall, the book provides students, researchers, and clinicians alike a comprehensive overview of interdisciplinary approaches to cancer diagnosis.
| Author | : Gorachand Dutta |
| Publisher | : Springer Nature |
| Total Pages | : 252 |
| Release | : 2022-12-02 |
| Genre | : Science |
| ISBN | : 9811971307 |
This book reviews the potential of next-generation point-of-care diagnosis in healthcare. It also discusses the printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive biomarkers detection. The book presents the development of sensory systems based on the use of nanomaterials. It examines different biosensors for medical diagnosis using surface modification strategies of transducers. It presents electrochemical concepts based on different nanobiomaterials and nanocomposites for cancer theranostics. Notably, the book examines the recent advances in wearable, cost-effective hemodynamic sensors to detect diseases at an early stage. It further explores the combination of redox cycling and electrochemical detection to develop ultrasensitive and reproducible biosensors for point-of-care testing. Finally, the book summarizes the significant challenges in the point of care diagnostics and its future opportunities in healthcare.
