Multiple Testing Problems in Pharmaceutical Statistics

Multiple Testing Problems in Pharmaceutical Statistics
Author: Alex Dmitrienko
Publisher: CRC Press
Total Pages: 323
Release: 2009-12-08
Genre: Mathematics
ISBN: 1584889853

Useful Statistical Approaches for Addressing Multiplicity IssuesIncludes practical examples from recent trials Bringing together leading statisticians, scientists, and clinicians from the pharmaceutical industry, academia, and regulatory agencies, Multiple Testing Problems in Pharmaceutical Statistics explores the rapidly growing area of multiple c

Statistical Power Analysis for the Behavioral Sciences

Statistical Power Analysis for the Behavioral Sciences
Author: Jacob Cohen
Publisher: Routledge
Total Pages: 625
Release: 2013-05-13
Genre: Psychology
ISBN: 1134742770

Statistical Power Analysis is a nontechnical guide to power analysis in research planning that provides users of applied statistics with the tools they need for more effective analysis. The Second Edition includes: * a chapter covering power analysis in set correlation and multivariate methods; * a chapter considering effect size, psychometric reliability, and the efficacy of "qualifying" dependent variables and; * expanded power and sample size tables for multiple regression/correlation.

Resampling-Based Multiple Testing

Resampling-Based Multiple Testing
Author: Peter H. Westfall
Publisher: John Wiley & Sons
Total Pages: 382
Release: 1993-01-12
Genre: Mathematics
ISBN: 9780471557616

Combines recent developments in resampling technology (including the bootstrap) with new methods for multiple testing that are easy to use, convenient to report and widely applicable. Software from SAS Institute is available to execute many of the methods and programming is straightforward for other applications. Explains how to summarize results using adjusted p-values which do not necessitate cumbersome table look-ups. Demonstrates how to incorporate logical constraints among hypotheses, further improving power.

Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book

Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book
Author: Richard A. McPherson
Publisher: Elsevier Health Sciences
Total Pages: 1769
Release: 2011-09-06
Genre: Medical
ISBN: 1455726842

Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test selection and interpretation of results. Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! A user-friendly full-color layout puts all the latest, most essential knowledge at your fingertips. Update your understanding of the scientific foundation and clinical application of today's complete range of laboratory tests. Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection. Reference the information you need quickly and easily thanks to a full-color layout, many new color illustrations and visual aids, and an organization by organ system. Master all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke disorders; coagulation testing for antiplatelet drugs such as aspirin and clopidogrel; biochemical markers of bone metabolism; clinical enzymology; hematology and transfusion medicine; medical microbiology; body fluid analysis; and many other rapidly evolving frontiers in the field. Effectively monitor the pace of drug clearing in patients undergoing pharmacogenomic treatments with a new chapter on this groundbreaking new area. Apply the latest best practices in clinical laboratory management with special chapters on organization, work flow, quality control, interpretation of results, informatics, financial management, and establishing a molecular diagnostics laboratory. Confidently prepare for the upcoming recertification exams for clinical pathologists set to begin in 2016.

Principles and Practice of Structural Equation Modeling

Principles and Practice of Structural Equation Modeling
Author: Rex B. Kline
Publisher: Guilford Publications
Total Pages: 554
Release: 2015-10-08
Genre: Social Science
ISBN: 1462523005

This book has been replaced by Principles and Practice of Structural Equation Modeling, Fifth Edition, ISBN 978-1-4625-5191-0.

Principles and Applications of Molecular Diagnostics

Principles and Applications of Molecular Diagnostics
Author: Nader Rifai
Publisher: Elsevier
Total Pages: 424
Release: 2018-06-13
Genre: Science
ISBN: 0128160624

Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor cells, and plasma DNA; the second half presents clinical applications of molecular diagnostics in genetic disease, infectious disease, hematopoietic malignancies, solid tumors, prenatal diagnosis, pharmacogenetics, and identity testing. A thorough yet succinct guide to using molecular testing technology, Principles and Applications of Molecular Diagnostics is an essential resource for laboratory professionals, biologists, chemists, pharmaceutical and biotech researchers, and manufacturers of molecular diagnostics kits and instruments. - Explains the principles and tools of molecular biology - Describes standard and state-of-the-art molecular techniques for obtaining qualitative and quantitative results - Provides a detailed description of current molecular applications used to solve diagnostics tasks

Henry's Clinical Diagnosis and Management by Laboratory Methods: First South Asia Edition_E-book

Henry's Clinical Diagnosis and Management by Laboratory Methods: First South Asia Edition_E-book
Author: Richard A. McPherson
Publisher: Elsevier Health Sciences
Total Pages: 1820
Release: 2016-08-31
Genre: Medical
ISBN: 8131246779

To interpret the laboratory results. To distinguish the normal from the abnormal and to understand the merits and demerits of the assays under study. The book attempts to train a laboratory medicine student to achievesound knowledge of analytical methods and quality control practices, tointerpret the laboratory results, to distinguish the normal from the abnormaland to understand the merits and demerits of the assays under study.

Principles of Performance and Reliability Modeling and Evaluation

Principles of Performance and Reliability Modeling and Evaluation
Author: Lance Fiondella
Publisher: Springer
Total Pages: 659
Release: 2016-04-06
Genre: Technology & Engineering
ISBN: 3319305999

This book presents the latest key research into the performance and reliability aspects of dependable fault-tolerant systems and features commentary on the fields studied by Prof. Kishor S. Trivedi during his distinguished career. Analyzing system evaluation as a fundamental tenet in the design of modern systems, this book uses performance and dependability as common measures and covers novel ideas, methods, algorithms, techniques, and tools for the in-depth study of the performance and reliability aspects of dependable fault-tolerant systems. It identifies the current challenges that designers and practitioners must face in order to ensure the reliability, availability, and performance of systems, with special focus on their dynamic behaviors and dependencies, and provides system researchers, performance analysts, and practitioners with the tools to address these challenges in their work. With contributions from Prof. Trivedi's former PhD students and collaborators, many of whom are internationally recognized experts, to honor him on the occasion of his 70th birthday, this book serves as a valuable resource for all engineering disciplines, including electrical, computer, civil, mechanical, and industrial engineering as well as production and manufacturing.

Practical Statistical Power Analysis

Practical Statistical Power Analysis
Author: Zhiyong Zhang
Publisher: Isdsa Press
Total Pages: 358
Release: 2018-05
Genre:
ISBN: 9781946728029

The importance of conducting a statistical power analysis at the beginning of a study is universally accepted. Without careful planning, a study can easily fail to detect an existing effect by chance. This book teaches how to conduct power analysis for a range of models from correlation and t-test to structural equation models and multilevel models. Both a graphical Web software WebPower and an R package are introduced to practically conduct the analysis.