Application Of Surface Enhanced Raman Spectroscopy To Biological Systems
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| Author | : M. Ghomi |
| Publisher | : IOS Press |
| Total Pages | : 204 |
| Release | : 2012-02-23 |
| Genre | : Medical |
| ISBN | : 1614990204 |
Raman spectroscopy has been known and used as a technique for 80 years, originally for the study of inorganic substances. Recent advances in underlying technology, such as lasers, detectors, filters and components, have transformed the technique into a very effective modern tool for studying complex biological problems. Professor Mahmoud Ghomi (of the University of Paris XIII) has edited this book on the applications of Raman spectroscopy to biology, covering in a readily accessible way the area from basic studies to the diagnosis of disease. The early chapters provide background information on basic principles underlying the main Raman methods covered in the book, with information on Surface-Enhanced Raman Scattering (SERS) and Surface-Enhanced Fluorescence (SEF), as well as giving accounts of applications to biomolecular and cellular investigations. Among the topics covered are studies of drugs and their complexes with biomolecules on nanoparticles, application of SERS to blood analysis, studies of single cells and of applications to human cancer diagnostics.This will be a useful book for experimental scientists in academic, governmental, industrial and clinical environments and for those entering the field of biomolecular spectroscopy.
| Author | : Yuling Wang |
| Publisher | : Elsevier |
| Total Pages | : 596 |
| Release | : 2021-02-15 |
| Genre | : Science |
| ISBN | : 9780128211212 |
Principles and Clinical Diagnostic Applications of Surface-Enhanced Raman Spectroscopy summaries the principles of SERS and nanoplasmonic materials for SERS, with a focus on applications in clinical diagnostics. This book covers the fundamentals of SERS, materials, experimental aspects and applications of SERS in clinical diagnostics, with discussions on label-free/direct SERS assay, design and synthesis of SERS nanotags, SERS nanotags for point-of-care diagnostics, microfluidic SERS assay, and in vitro and in vivo sensing and imaging. Written by subject experts, this comprehensive volume showcases recent progress in SERS applications in clinical diagnostics, thus helping readers understand when and how to use SERS in a clinical setting. Introduces the basics of SERS/SERS nanotags and suitable nanomaterials for SERS applications Gives an overview on the cutting-edge research on SERS applications for clinical diagnosis, including the latest advances in our understanding of underlying principles to enable material design and clinical applications Gradually builds from the fundamental concepts to the applications of SERS for clinical diagnostics
| Author | : Mahmoud Ghomi |
| Publisher | : IOS Press |
| Total Pages | : 204 |
| Release | : 2012 |
| Genre | : Medical |
| ISBN | : 1607509997 |
| Author | : Ricardo Aroca |
| Publisher | : John Wiley & Sons |
| Total Pages | : 260 |
| Release | : 2006-05-01 |
| Genre | : Science |
| ISBN | : 9780470035658 |
Surface Enhanced Vibrational Spectroscopy (SEVS) has reached maturity as an analytical technique, but until now there has been no single work that describes the theory and experiments of SEVS. This book combines the two important techniques of surface-enhanced Raman scattering (SERS) and surface-enhanced infrared (SEIR) into one text that serves as the definitive resource on SEVS. Discusses both the theory and the applications of SEVS and provides an up-to-date study of the state of the art Offers interpretations of SEVS spectra for practicing analysts Discusses interpretation of SEVS spectra, which can often be very different to the non-enhanced spectrum - aids the practicing analyst
| Author | : Eric Le Ru |
| Publisher | : Elsevier |
| Total Pages | : 688 |
| Release | : 2008-11-17 |
| Genre | : Science |
| ISBN | : 0080931553 |
SERS was discovered in the 1970s and has since grown enormously in breadth, depth, and understanding. One of the major characteristics of SERS is its interdisciplinary nature: it lies at the boundary between physics, chemistry, colloid science, plasmonics, nanotechnology, and biology. By their very nature, it is impossible to find a textbook that will summarize the principles needed for SERS of these rather dissimilar and disconnected topics. Although a basic understanding of these topics is necessary for research projects in SERS with all its many aspects and applications, they are seldom touched upon as a coherent unit during most undergraduate studies in physics or chemistry. This book intends to fill this existing gap in the literature. It provides an overview of the underlying principles of SERS, from the fundamental understanding of the effect to its potential applications. It is aimed primarily at newcomers to the field, graduate students, researchers or scientists, attracted by the many applications of SERS and plasmonics or its basic science. The emphasis is on concepts and background material for SERS, such as Raman spectroscopy, the physics of plasmons, or colloid science, all of them introduced within the context of SERS, and from where the more specialized literature can be followed. - Represents one of very few books fully dedicated to the topic of surface-enhanced Raman spectroscopy (SERS) - Gives a comprehensive summary of the underlying physical concepts around SERS - Provides a detailed analysis of plasmons and plasmonics
| Author | : Marek Prochazka |
| Publisher | : Springer |
| Total Pages | : 230 |
| Release | : 2015-12-12 |
| Genre | : Science |
| ISBN | : 3319239929 |
This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.
| Author | : Yuling Wang |
| Publisher | : Elsevier |
| Total Pages | : 465 |
| Release | : 2021-09-17 |
| Genre | : Science |
| ISBN | : 012823198X |
Principles and Clinical Diagnostic Applications of Surface-Enhanced Raman Spectroscopy summarizes the principles of surface-enhanced Raman scattering/spectroscopy (SERS) and plasmonic nanomaterials for SERS, with a focus on SERS applications in clinical diagnostics. This book covers the key concepts from the fundamentals, materials, experimental aspects, and applications of SERS in clinical diagnostics with discussions on label-free/direct SERS assay, design and synthesis of SERS nanotags, SERS nanotags for point-of-care diagnostics, microfluidic SERS assay, and in vitro and in vivo sensing and imaging. Written by experts from around the world, this comprehensive volume showcases the recent progress of SERS applications in clinical diagnostics and helps readers understand when and how to use SERS in a clinical setting. - Introduces the basics of SERS and suitable nanomaterials for SERS application - Gives an overview of the cutting-edge research on SERS applications for clinical diagnosis, including the latest advances in our understanding of underlying principles to enable material design and clinical applications - Gradually builds from the fundamental concepts to the applications of SERS for clinical diagnostics
| Author | : Katrin Kneipp |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 473 |
| Release | : 2006-06-21 |
| Genre | : Science |
| ISBN | : 3540335676 |
Almost 30 years after the first reports on surface-enhanced Raman signals, the phenomenon of surface-enhanced Raman scattering (SERS) is now well established. SERS gained particular interest after single-molecule Raman spectroscopy had been demonstrated. This book summarizes and discusses present theoretical approaches that explain the phenomenon of SERS and reports on new and exciting experiments and applications of the fascinating spectroscopic effect.
| Author | : Zhong-Qun Tian |
| Publisher | : John Wiley & Sons Incorporated |
| Total Pages | : 400 |
| Release | : 2010-06-14 |
| Genre | : Science |
| ISBN | : 9780470068083 |
Surface-Enhanced Raman Spectroscopy: Principles, Experiments, and Applications is a comprehensive, up to date, and balanced treatment of the theoretical and practical aspects of Surface-Enhanced Raman Scattering (SERS), a useful branch of spectroscopy for several areas of science. This book describes the basic principles of SERS, including SERS mechanisms, performing SERS measurements, and interpreting data. Also emphasized are applications in electrochemistry; catalysis; surface processing and corrosion; Self-Assemble-Layer and L-B Films; polymer science; biology; medicine and drug analysis; sensors; fuel cells; forensics; and archaeology. It is an essential guide for student and professional analytical chemists.
| Author | : Swati Jain |
| Publisher | : Bentham Science Publishers |
| Total Pages | : 263 |
| Release | : 2021-12-28 |
| Genre | : Science |
| ISBN | : 9815039121 |
Surface enhanced Raman spectroscopy (SERS) is a technique applied in multidisciplinary research. Its use has tremendously grown in the last 40 years owing to improved nanofabrication, biomolecules extraction and sensitive signal acquisition techniques. This book focuses on the underlying principles of SERS by emphasizing on basic concepts and background information about the subject. Chapters explain the physics of Raman spectroscopy while also indicating its relevance to designing protocols and methodologies for biosensing and imaging. The book gives updated and recent details on colloids and nanostructures, their fabrication, surface engineering and immobilization methods, all in context to SERS based biosensing. Key Features: - Covers basic knowledge and new research about surface enhanced Raman spectroscopy (SERS) - Provides a complete framework on SERS based biosensing with concise chapters - Focuses on different active molecules critical to SERS and associated developed nanoassemblies - Presents information about ongoing research on SERS imaging applications - Highlights bottlenecks of SERS technique in biosensing - Includes references for further reading This book serves as a reference book for researchers and academicians and will also provide a reasonable understanding on the topic of SERS to newcomers irrespective of their background in a simple manner. The book is of interest to all readers within the scientific community involved with Raman spectroscopy, including chemists, physicists, biologists, material scientists as well as biomedical engineers.
