Application Of Signal Processing And Soft Computing To Genomics
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| Author | : Ilya Shmulevich |
| Publisher | : Princeton University Press |
| Total Pages | : 314 |
| Release | : 2014-09-08 |
| Genre | : Science |
| ISBN | : 1400865263 |
Genomic signal processing (GSP) can be defined as the analysis, processing, and use of genomic signals to gain biological knowledge, and the translation of that knowledge into systems-based applications that can be used to diagnose and treat genetic diseases. Situated at the crossroads of engineering, biology, mathematics, statistics, and computer science, GSP requires the development of both nonlinear dynamical models that adequately represent genomic regulation, and diagnostic and therapeutic tools based on these models. This book facilitates these developments by providing rigorous mathematical definitions and propositions for the main elements of GSP and by paying attention to the validity of models relative to the data. Ilya Shmulevich and Edward Dougherty cover real-world situations and explain their mathematical modeling in relation to systems biology and systems medicine. Genomic Signal Processing makes a major contribution to computational biology, systems biology, and translational genomics by providing a self-contained explanation of the fundamental mathematical issues facing researchers in four areas: classification, clustering, network modeling, and network intervention.
| Author | : Ajith Abraham |
| Publisher | : Springer Nature |
| Total Pages | : 931 |
| Release | : 2023-03-27 |
| Genre | : Technology & Engineering |
| ISBN | : 3031275241 |
This book highlights the recent research on soft computing, pattern recognition, nature-inspired computing, and their various practical applications. It presents 69 selected papers from the 14th International Conference on Soft Computing and Pattern Recognition (SoCPaR 2022) and 19 papers from the 14th World Congress on Nature and Biologically Inspired Computing (NaBIC 2022), which was held online, from December 14 to 16, 2022. A premier conference in the field of soft computing, artificial intelligence, and machine learning applications, SoCPaR-NaBIC 2022 brought together researchers, engineers, and practitioners whose work involves intelligent systems, network security, and their applications in industry. Including contributions by authors from over 25 countries, the book offers a valuable reference guide for all researchers, students, and practitioners in the fields of computer science and engineering.
| Author | : Bhanu Prasad |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 384 |
| Release | : 2008-03-20 |
| Genre | : Computers |
| ISBN | : 3540774645 |
Softcomputing techniques play a vital role in the industry. This book presents several important papers presented by some of the well-known scientists from all over the globe. The main techniques of soft computing presented include ant-colony optimization, artificial immune systems, artificial neural networks, Bayesian models. The book includes various examples and application domains such as bioinformatics, detection of phishing attacks, and fault detection of motors.
| Author | : Md. Zia Ur Rahman |
| Publisher | : CRC Press |
| Total Pages | : 202 |
| Release | : 2021-06-30 |
| Genre | : Science |
| ISBN | : 1000375153 |
This book addresses the issue of improving the accuracy in exon prediction in DNA sequences using various adaptive techniques based on different performance measures that are crucial in disease diagnosis and therapy. First, the authors present an overview of genomics engineering, structure of DNA sequence and its building blocks, genetic information flow in a cell, gene prediction along with its significance, and various types of gene prediction methods, followed by a review of literature starting with the biological background of genomic sequence analysis. Next, they cover various theoretical considerations of adaptive filtering techniques used for DNA analysis, with an introduction to adaptive filtering, properties of adaptive algorithms, and the need for development of adaptive exon predictors (AEPs) and structure of AEP used for DNA analysis. Then, they extend the approach of least mean squares (LMS) algorithm and its sign-based realizations with normalization factor for DNA analysis. They also present the normalized logarithmic-based realizations of least mean logarithmic squares (LMLS) and least logarithmic absolute difference (LLAD) adaptive algorithms that include normalized LMLS (NLMLS) algorithm, normalized LLAD (NLLAD) algorithm, and their signed variants. This book ends with an overview of the goals achieved and highlights the primary achievements using all proposed techniques. This book is intended to provide rigorous use of adaptive signal processing algorithms for genetic engineering, biomedical engineering, and bioinformatics and is useful for undergraduate and postgraduate students. This will also serve as a practical guide for Ph.D. students and researchers and will provide a number of research directions for further work. Features Presents an overview of genomics engineering, structure of DNA sequence and its building blocks, genetic information flow in a cell, gene prediction along with its significance, and various types of gene prediction methods Covers various theoretical considerations of adaptive filtering techniques used for DNA analysis, introduction to adaptive filtering, properties of adaptive algorithms, need for development of adaptive exon predictors (AEPs), and structure of AEP used for DNA analysis Extends the approach of LMS algorithm and its sign-based realizations with normalization factor for DNA analysis Presents the normalized logarithmic-based realizations of LMLS and LLAD adaptive algorithms that include normalized LMLS (NLMLS) algorithm, normalized LLAD (NLLAD) algorithm, and their signed variants Provides an overview of the goals achieved and highlights the primary achievements using all proposed techniques Dr. Md. Zia Ur Rahman is a professor in the Department of Electronics and Communication Engineering at Koneru Lakshmaiah Educational Foundation (K. L. University), Guntur, India. His current research interests include adaptive signal processing, biomedical signal processing, genetic engineering, medical imaging, array signal processing, medical telemetry, and nanophotonics. Dr. Srinivasareddy Putluri is currently a Software Engineer at Tata Consultancy Services Ltd., Hyderabad. He received his Ph.D. degree (Genomic Signal Processing using Adaptive Signal Processing algorithms) from the Department of Electronics and Communication Engineering at Koneru Lakshmaiah Educational Foundation (K. L. University), Guntur, India. His research interests include genomic signal processing and adaptive signal processing. He has published 15 research papers in various journals and proceedings. He is currently a reviewer of publishers like the IEEE Access and IGI.
| Author | : B. V. Babu |
| Publisher | : Springer |
| Total Pages | : 1529 |
| Release | : 2014-07-08 |
| Genre | : Technology & Engineering |
| ISBN | : 8132216024 |
The present book is based on the research papers presented in the International Conference on Soft Computing for Problem Solving (SocProS 2012), held at JK Lakshmipat University, Jaipur, India. This book provides the latest developments in the area of soft computing and covers a variety of topics, including mathematical modeling, image processing, optimization, swarm intelligence, evolutionary algorithms, fuzzy logic, neural networks, forecasting, data mining, etc. The objective of the book is to familiarize the reader with the latest scientific developments that are taking place in various fields and the latest sophisticated problem solving tools that are being developed to deal with the complex and intricate problems that are otherwise difficult to solve by the usual and traditional methods. The book is directed to the researchers and scientists engaged in various fields of Science and Technology.
| Author | : Millie Pant |
| Publisher | : Springer Nature |
| Total Pages | : 1403 |
| Release | : 2020-02-24 |
| Genre | : Technology & Engineering |
| ISBN | : 9811507511 |
The book focuses on soft computing and its applications to solve real-world problems in different domains, ranging from medicine and health care, to supply chain management, image processing and cryptanalysis. It includes high-quality papers presented at the International Conference on Soft Computing: Theories and Applications (SoCTA 2018), organized by Dr. B. R. Ambedkar National Institute of Technology, Jalandhar, Punjab, India. Offering significant insights into soft computing for teachers and researchers alike, the book inspires more researchers to work in the field of soft computing.
| Author | : George Jabboure Netto |
| Publisher | : Springer |
| Total Pages | : 631 |
| Release | : 2018-12-10 |
| Genre | : Medical |
| ISBN | : 3319968300 |
​The recent advances in genomics are continuing to reshape our approach to diagnostics, prognostics and therapeutics in oncologic and other disorders. A paradigm shift in pharmacogenomics and in the diagnosis of genetic inherited diseases and infectious diseases is unfolding as the result of implementation of next generation genomic technologies. With rapidly growing knowledge and applications driving this revolution, along with significant technologic and cost changes, genomic approaches are becoming the primary methods in many laboratories and for many diseases. As a result, a plethora of clinical genomic applications have been implemented in diagnostic pathology laboratories, and the applications and demands continue to evolve rapidly. This has created a tremendous need for a comprehensive resource on genomic applications in clinical and anatomic pathology. We believe that our current textbook provides such a resource to practicing molecular pathologists, hematopathologists and other subspecialized pathologists, general pathologists, pathology and other trainees, oncologists, geneticists and a growing spectrum of other clinicians. With periodic updates and a sufficiently rapid time from submission to publication, this textbook will be the resource of choice for many professionals and teaching programs. Its focus on genomics parallels the evolution of these technologies as primary methods in the clinical lab. The rapid evolution of genomics and its applications in medicine necessitates the (frequent) updating of this publication. This text will provide a state-of-the art review of the scientific principles underlying next generation genomic technologies and the required bioinformatics approaches to analyses of the daunting amount of data generated by current and emerging genomic technologies. Implementation roadmaps for various clinical assays such as single gene, gene panels, whole exome and whole genome assays will be discussed together with issues related to reporting and the pathologist’s role in interpretation and clinical integration of genomic tests results. Genomic applications for site-specific solid tumors and hematologic neoplasms will be detailed. Genomic applications in pharmacogenomics, inherited genetic diseases and infectious diseases will also be discussed. The latest iteration of practice recommendations or guidelines in genomic testing put forth by stakeholder professional organizations such as the College of American Pathology and the Association for Molecular Pathology, will be discussed as well as regulatory issues and laboratory accreditation related to genomic testing. All chapters will be written by experts in their fields and will include the most up to date scientific and clinical information.
| Author | : Tarun K. Sharma |
| Publisher | : Springer Nature |
| Total Pages | : 572 |
| Release | : 2021-06-26 |
| Genre | : Technology & Engineering |
| ISBN | : 9811616965 |
This book focuses on soft computing and how it can be applied to solve real-world problems arising in various domains, ranging from medicine and healthcare, to supply chain management, image processing and cryptanalysis. It gathers high-quality papers presented at the International Conference on Soft Computing: Theories and Applications (SoCTA 2020), organized online. The book is divided into two volumes and offers valuable insights into soft computing for teachers and researchers alike; the book will inspire further research in this dynamic field.
| Author | : Edward R. Dougherty |
| Publisher | : Hindawi Publishing Corporation |
| Total Pages | : 456 |
| Release | : 2005 |
| Genre | : DNA microarrays |
| ISBN | : 9775945070 |
Recent advances in genomic studies have stimulated synergetic research and development in many cross-disciplinary areas. Processing the vast genomic data, especially the recent large-scale microarray gene expression data, to reveal the complex biological functionality, represents enormous challenges to signal processing and statistics. This perspective naturally leads to a new field, genomic signal processing (GSP), which studies the processing of genomic signals by integrating the theory of signal processing and statistics. Written by an international, interdisciplinary team of authors, this invaluable edited volume is accessible to students just entering this emergent field, and to researchers, both in academia and in industry, in the fields of molecular biology, engineering, statistics, and signal processing. The book provides tutorial-level overviews and addresses the specific needs of genomic signal processing students and researchers as a reference book. The book aims to address current genomic challenges by exploiting potential synergies between genomics, signal processing, and statistics, with special emphasis on signal processing and statistical tools for structural and functional understanding of genomic data. The first part of this book provides a brief history of genomic research and a background introduction from both biological and signal-processing/statistical perspectives, so that readers can easily follow the material presented in the rest of the book. In what follows, overviews of state-of-the-art techniques are provided. We start with a chapter on sequence analysis, and follow with chapters on feature selection, classification, and clustering of microarray data. We then discuss the modeling, analysis, and simulation of biological regulatory networks, especially gene regulatory networks based on Boolean and Bayesian approaches. Visualization and compression of gene data, and supercomputer implementation of genomic signal processing systems are also treated. Finally, we discuss systems biology and medical applications of genomic research as well as the future trends in genomic signal processing and statistics research.
| Author | : Pandian Vasant |
| Publisher | : IGI Global |
| Total Pages | : 1173 |
| Release | : 2013-08-31 |
| Genre | : Technology & Engineering |
| ISBN | : 1466644516 |
"This book explores emerging technologies and best practices designed to effectively address concerns inherent in properly optimizing advanced systems, demonstrating applications in areas such as bio-engineering, space exploration, industrial informatics, information security, and nuclear and renewable energies"--Provided by publisher.
