Application of Biomarkers in Cancer Epidemiology

Application of Biomarkers in Cancer Epidemiology
Author: P. Toniolo
Publisher:
Total Pages: 340
Release: 1997
Genre: Medical
ISBN:

This publication originates from an international workshop which addresses a range of methodological issues underlying the use of biological markers of exposure, biological effects and individual susceptibility in cancer epidemiology. It includes a report of the workshop, with a general discussion and recommendation on epidemiology. a series of peer-reviewed authored contributors provide a more personal view on the most important aspects by key researchers.

Cancer Epidemiology and Prevention

Cancer Epidemiology and Prevention
Author: Michael Thun
Publisher: Oxford University Press
Total Pages: 1329
Release: 2017-11-07
Genre: Medical
ISBN: 0190238674

"The definitive reference for budding and experienced cancer epidemiologists alike." -American Journal of Epidemiology "Practitioners in epidemiology and oncology will find immense value in this." -JAMA Since its initial publication in 1982, CANCER EPIDEMIOLOGY AND PREVENTION has served as the premier reference work for students and professionals working to understand the causes and prevention of cancer in humans. Now revised for the first time in more than a decade, this fourth edition provides a comprehensive summary of the global patterns of cancer incidence and mortality, current understanding of the major causal determinants, and a rationale for preventive interventions. Special attention is paid to molecular epidemiologic approaches that address the wider role of genetic predisposition and gene-environment interactions in cancer etiology and pathogenesis. New and timely chapters on environmental and social-epidemiologic factors include: · The role of social class disparities · The role of obesity and physical inactivity · The potential effects of electromagnetic fields and radiofrequency radiation · The principles of cancer chemoprevention For both seasoned professionals and newer generations of students and researchers, this fourth edition of CANCER EPIDEMIOLOGY AND PREVENTION remains the authority in the field -- a work of distinction that every lab, library, student, professional, or researcher should have close at hand.

Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease

Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 335
Release: 2010-06-25
Genre: Medical
ISBN: 0309157277

Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, but that is not always the case. The IOM recommends that the FDA adopt a consistent scientific framework for biomarker evaluation in order to achieve a rigorous and transparent process.

Textbook of Cancer Epidemiology

Textbook of Cancer Epidemiology
Author: Hans-Olov Adami
Publisher: Oxford University Press
Total Pages: 753
Release: 2018-01-09
Genre: Medical
ISBN: 0190676833

"Comprehensive and comprehensible, but also encouraging -- informed by the hope and belief that informed its creation." -Cancer Amid sweeping advances in the science and treatment of cancer, the TEXTBOOK OF CANCER EPIDEMIOLOGY offers students and professionals a definitive, systematic resource for understanding the factors affecting all types of human cancer. This fully updated new edition offers an overview of epidemiology's key concepts and methods as they relate to cancer (including the emerging potential of biomarkers) as well as site-specific chapters on individual cancers' natural history, pathology, descriptive epidemiology, and etiology. Taken together, these chapters forge connections between established science and the ongoing evolution of this dynamic field. Crisply and concisely written by an assembly of internationally recognized researchers, the TEXTBOOK OF CANCER EPIDEMIOLOGY offers a superlative introduction to the subject's consensuses and controversies for those embarking on their careers and a ready reference for seasoned professionals.

Analysis of Cancer Risks in Populations Near Nuclear Facilities

Analysis of Cancer Risks in Populations Near Nuclear Facilities
Author: National Research Council
Publisher: National Academies Press
Total Pages: 424
Release: 2012-06-29
Genre: Medical
ISBN: 0309255716

In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.

Cancer Epidemiology Among Asian Americans

Cancer Epidemiology Among Asian Americans
Author: Anna H. Wu
Publisher: Springer
Total Pages: 295
Release: 2016-10-14
Genre: Medical
ISBN: 3319411187

Cancer Epidemiology in Asian Americans is a comprehensive volume that provides the most current research on cancer etiology within this fast growing population sub-group in the United States. The book explores epidemiologic methods that are typically used in migrant studies, providing descriptive epidemiology of cancer patterns separately in Chinese, Japanese, Filipino and other Asian ethnic groups including Asian Indians, Koreans, Vietnamese, and other Southeast Asians. A major focus of the volume provides reviews of analytic risk factors for specific cancer sites including lung, colorectal, prostate, breast, liver and more. These chapters aim to explain the increases or decreases in incidence rates of various cancers upon migration, paying attention to changing risk factor prevalence, the importance of timing of exposures, and other co-factors important in the etiology of these cancers. Genetic determinants and gene-environment relationships associated with specific cancers are also discussed.. This first of its kind volume that is devoted to studies of cancer in Asian Americans provides a foundation to better understanding of environmental and lifestyle causes of cancer in this group, identifying gaps in our knowledge, and potential strategies for prevention.

Pathology and Epidemiology of Cancer

Pathology and Epidemiology of Cancer
Author: Massimo Loda
Publisher: Springer
Total Pages: 664
Release: 2016-09-01
Genre: Medical
ISBN: 3319351532

This book integrates the disciplines of cancer pathology and epidemiology to provide a synergistic and complementary approach to understanding the molecular mechanisms of cancer. This book provides relevant information on the diagnostic, prognostic and predictive molecular pathology of cancer. Epidemiological studies, including descriptive epidemiology, risk factors and molecular mechanisms of disease inform on the etiology and progression of cancer. The text concentrates on major cancers that are currently prevalent and those for which substantial molecular, pathological and epidemiological data is available. Each section is designed to provide an overview of that cancer type in terms of basic biology, review the current epidemiological data surrounding that cancer type and provide information on common practices and challenges related to the molecular pathology of that cancer type. Several relevant techniques in molecular pathology, which facilitate diagnosis and treatment are also explored. Pathology and Epidemiology of Cancer provides a succinct and comprehensive overview of multiple cancer types to guide clinicians during patient care and to guide scientists for innovations in research. It represents an integral resource for pathologists, epidemiologists, medical students as well as translational, basic and clinical science researchers who are all working to progress the field of cancer in terms of diagnosis, treatment and prevention.

Biomarkers in Cancer Screening and Early Detection

Biomarkers in Cancer Screening and Early Detection
Author: Sudhir Srivastava
Publisher: John Wiley & Sons
Total Pages: 494
Release: 2017-06-07
Genre: Medical
ISBN: 1118468821

Prepared by world leaders on this topic, Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and use in developing personalized cancer treatment. Offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers Provides immediately actionable information and hopefully also inspiration to move discovery and clinical application forward Offers vital knowledge to help develop personalized cancer treatment for individual patients with specific cancers