Antioxidants In Human Health And Disease
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| Author | : Balz Frei |
| Publisher | : Academic Press |
| Total Pages | : 624 |
| Release | : 1994-09-22 |
| Genre | : Health & Fitness |
| ISBN | : |
This book serves as a comprehensive overview of the current scientific knowledge on the health effects of dietary and supplemental antioxidants (such as vitamins C and E). Chapters integrate information from basic research and animal studies, epidemiologic studies, and clinical intervention trials. The popular media has taken great interest in antioxidants, with numerous articles emphasizing their role in preventing disease and the possible slowing of the aging process. These antioxidant vitamins may be important in preventing not only acute deficiency symptoms, but also chronic disorders such as heart disease and certain types of cancer. This book, therefore, is not only for scientists and doctors, but also for health writers, journalists, and informed lay people. The text focuses on several human conditions for which there is now good scientific evidence that oxidation is an important etiological component. Specifically, antioxidants may prevent or slow down the progression of: Cancer, Cardiovascular disease, Immune system disorders, Cataracts, Neurological disorders, Degeneration due to the aging process.
| Author | : Silvana Andreescu |
| Publisher | : ACS Symposium |
| Total Pages | : 0 |
| Release | : 2016-08 |
| Genre | : Science |
| ISBN | : 9780841231009 |
This book provides a comprehensive overview of the oxidative stress related mechanisms in biological systems and the involvement of reactive oxygen and nitrogen species (ROS and RNS), the damage of DNA, proteins, and lipids caused by oxidative stress, the protection of cells and tissues against free radicals, the relation of the oxidative stress to aging and human diseases including cancer and neurological disorders, and the development of new therapeutic approaches to modulate oxidative stress. The current state-of-the-art methodologies including the development of sensors and biosensors for the detection of ROS/RNS and of biomarkers of oxidative stress are also discussed. The book is organized in three overlapping parts, starting with general considerations of the oxidative stress, homeostasis pathways, and ROS mechanisms, followed by chapters discussing the involvement of ROS in particular diseases and concluding with analytical aspects of oxidative stress monitoring. The book provides a solid background on oxidative stress and ROS/RNS generation for novice learners while also offering scientists and practitioners already involved in this field a wealth of information covering the most recent developments in the study of oxidative stress, the role of radical species, novel antioxidant therapies, and methods for assessing free radicals and oxidative stress.
| Author | : Vibha Rani |
| Publisher | : Springer |
| Total Pages | : 427 |
| Release | : 2014-11-14 |
| Genre | : Science |
| ISBN | : 8132220358 |
The role of oxidative stress in human disease has become an area of intense interest. Free radicals, a normal product of metabolism, exist in all aerobic cells in balance with biochemical antioxidants. Environmental stress increases the levels of free radicals drastically, thereby disturbing the equilibrium between free radical production and the antioxidant capability causing oxidative stress. Over the years, ROS has been implicated in the pathologies of various diseases like cancer, neurological disorder, cardiovascular diseases rheumatoid arthritis, diabetes etc. This book provides an in depth critical state-of-art reviews from established investigators on free radicals, ROS associated pathogenesis of human diseases, biomarkers of oxidative damage, antioxidants, phytonutrients and other related health concerns of modern society. The present book is aimed at graduate students, researchers in academia, industry and clinicians with the interest in redox biology. Special attention has been devoted to the topic of ROS signalling, oxidative stress induced human pathologies & antioxidative therapies. The book consists of four parts in specified topics based on the current literatures for the better understanding of the readers with respect to their subject-wise interests. The first section of the book provides an overview about the ROS production and their measuring tools and techniques followed by the mechanisms involved in the oxidative stress in the second section. The third section describes the involvement of oxidative stress in different human diseases and the last section focuses on the different strategies to ameliorate oxidative stress induced stress.
| Author | : Antonis Zampelas |
| Publisher | : CRC Press |
| Total Pages | : 340 |
| Release | : 2015-06-09 |
| Genre | : Medical |
| ISBN | : 1466580119 |
Antioxidant use in health promotion and disease prevention either through dietary intake or supplementation is controversial. This book reviews the latest evidence-based research in the area, principally through prospective cohort studies and randomized controlled trials. It assesses major dietary antioxidants and discusses their use in diseases such as cancer, diabetes, stroke, coronary heart disease, HIV/AIDS, and neurodegenerative and immune diseases. The use of antioxidants in health is also discussed along with common adverse effects associated with antioxidant use.
| Author | : Lester Packer |
| Publisher | : Elsevier |
| Total Pages | : 539 |
| Release | : 1999-03-16 |
| Genre | : Technology & Engineering |
| ISBN | : 0080527280 |
Antioxidant Food Supplements in Human Health discusses new discoveries in the areas of oxygen and nitric oxide metabolism and pathophysiology, redox regulation and cell signaling, and the identification of natural antioxidants and their mechanisms of action on free radicals and their role in health and disease. An essential resource for researchers, students, and professionals in food science and nutrition, gerontology, physiology, pharmacology, and related areas. Health effects of antioxidant nutrients Nutrients of vitamins C and E, selenium, alpha-lipoic acid, coenzyme Q10, carotenoids, and flavonoids Natural source antioxidants, including pine bark, ginko biloba, wine, herbs,uyaku, and carica papaya
| Author | : Balz Frei |
| Publisher | : Academic Press |
| Total Pages | : 621 |
| Release | : 2012-12-02 |
| Genre | : Science |
| ISBN | : 0080571689 |
This book serves as a comprehensive overview of the current scientific knowledge on the health effects of dietary and supplemental antioxidants (such as vitamins C and E). Chapters integrate information from basic research and animal studies, epidemiologic studies, and clinical intervention trials. The popular media has taken great interest in antioxidants, with numerous articles emphasizing their role in preventing disease and the possible slowing of the aging process. These antioxidant vitamins may be important in preventing not only acute deficiency symptoms, but also chronic disorders such as heart disease and certain types of cancer. This book, therefore, is not only for scientists and doctors, but also for health writers, journalists, and informed lay people. The text focuses on several human conditions for which there is now good scientific evidence that oxidation is an important etiological component. Specifically, antioxidants may prevent or slow down the progression of: Cancer, Cardiovascular disease, Immune system disorders, Cataracts, Neurological disorders, Degeneration due to the aging process.
| Author | : Nina Pegg |
| Publisher | : |
| Total Pages | : 242 |
| Release | : 2020-09-15 |
| Genre | : Medical |
| ISBN | : 9781632418319 |
Living organisms require oxygen for survival, but it is also a highly reactive molecule that can damage organisms by producing reactive oxygen species. Oxidation is the chemical reaction that produces free radicals and thereby leads to chain reactions with the potential to damage the cells of organisms. Antioxidants inhibit oxidation. Ascorbic acid or thiols are antioxidants that can terminate these chain reactions. Organisms have a complex system of antioxidant metabolites and enzymes that work in tandem to prevent oxidative damage to DNA, proteins and lipids. However, reactive oxygen species have useful cellular functions as well, such as redox signaling. Antioxidant systems therefore do not remove oxidants completely but keep them at an optimum level. The role of oxidative stress in degenerative diseases, such as diabetes, kidney disease, neurological disorders, obesity, cancer and aging is understood. This makes antioxidant dietary supplements a potential strategy to overcome these conditions. This book provides comprehensive insights into antioxidants and their role in human health and disease. It will also provide interesting topics for research, which interested readers can take up. With state-of-the-art inputs by acclaimed experts of this field, this book targets students and professionals.
| Author | : Halina Maria Ekiert |
| Publisher | : Springer |
| Total Pages | : 861 |
| Release | : 2022-06-26 |
| Genre | : Science |
| ISBN | : 9783030781590 |
This book provides a comprehensive reference guide to plant-derived antioxidants, their beneficial effects, mechanisms of action, and role in disease prevention and improving general health (anti-ageing effect). The content is divided into three main parts, the first of which covers various antioxidants (such as polyphenols, carotenoids, tocopherols, tocotrienols, glutathione, ascorbic acid), their origins, plant biochemistry and industrial utilization. In turn, the book’s second, main part focuses on antioxidants’ beneficial health effects, explains biochemical fundamentals such as the free radical theory and oxidative stress, and discusses antioxidants’ role in e.g. cancer, cardiovascular diseases, inflammation, degenerative diseases and ageing. The third part reviews general laboratory methods for antioxidant screening, preservation and determination. Written by an international team of experts, this highly interdisciplinary book will benefit a broad range of health professionals and researchers working in biochemistry, biotechnology, nutrition, plant science and food chemistry. It offers an indispensable, up-to-date guide for anyone interested in antioxidants and the role of a plant-based diet in disease prevention and control
| Author | : Ronald Ross Watson |
| Publisher | : Academic Press |
| Total Pages | : 1504 |
| Release | : 2013-10-26 |
| Genre | : Science |
| ISBN | : 012398467X |
Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more. Explores neuronal protection by polyphenol metabolites and their application to medical care Defines modulation of enzyme actions to help researchers see and study polyphenols’ mechanisms of action, leading to clinical applications Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases
| Author | : Tapan Kumar Basu |
| Publisher | : Wallingford [England] : CABI Pub. |
| Total Pages | : 490 |
| Release | : 1999 |
| Genre | : Medical |
| ISBN | : |
Antioxidants and their mechanisms of action; Food factors as antioxidants; Coronary heart disease; Malignant disease; Other diseases; Indicators of oxidative stress; Consumer issues.
