Antioxidant-Based Therapies for Disease Prevention and Management

Antioxidant-Based Therapies for Disease Prevention and Management
Author: Pallavi Singh Chauhan
Publisher: CRC Press
Total Pages: 287
Release: 2021-12-23
Genre: Science
ISBN: 1000290387

This informative volume presents a valuable overview of the therapeutic aspects as well as applications of antioxidants. It discusses the basic mechanisms of therapy-based oxidative damage and categorization of nutritional antioxidants and covers the sources of antioxidants as well as their extraction and quantification. The volume considers the controversies of the usefulness or disadvantages of antioxidant supplementation in relation to adaptation and performance and also looks at the effectiveness of bioactives and antioxidant-based therapies for specific health issues, such as anemia, infectious diseases, urinary tract infections, Parkinson’s diseases, and diabetes. The book discusses the sensing of oxidative stress and the effectiveness of antioxidant treatment, followed by an introduction to several biomarkers to estimate the bioefficacy of dietary/supplemental antioxidants in various forms. Also considered are free radicals that can cause “oxidative stress,” a process that can trigger cell damage, and how antioxidant molecules have been shown to counteract oxidative stress in laboratory experiments.

Antioxidant-Based Therapies for Disease Prevention and Management

Antioxidant-Based Therapies for Disease Prevention and Management
Author: Pallavi Singh Chauhan
Publisher: CRC Press
Total Pages: 296
Release: 2021-12-22
Genre: Medical
ISBN: 1000290328

This informative volume presents a valuable overview of the therapeutic aspects as well as applications of antioxidants. It discusses the basic mechanisms of therapy-based oxidative damage and categorization of nutritional antioxidants and covers the sources of antioxidants as well as their extraction and quantification. The volume considers the controversies of the usefulness or disadvantages of antioxidant supplementation in relation to adaptation and performance and also looks at the effectiveness of bioactives and antioxidant-based therapies for specific health issues, such as anemia, infectious diseases, urinary tract infections, Parkinson’s diseases, and diabetes. The book discusses the sensing of oxidative stress and the effectiveness of antioxidant treatment, followed by an introduction to several biomarkers to estimate the bioefficacy of dietary/supplemental antioxidants in various forms. Also considered are free radicals that can cause “oxidative stress,” a process that can trigger cell damage, and how antioxidant molecules have been shown to counteract oxidative stress in laboratory experiments.

Nutritional Antioxidant Therapies: Treatments and Perspectives

Nutritional Antioxidant Therapies: Treatments and Perspectives
Author: Kaïs Hussain Al-Gubory
Publisher: Springer
Total Pages: 572
Release: 2018-03-10
Genre: Medical
ISBN: 3319676253

This book offers a collection of expert reviews on the use of plant-based antioxidant therapies in disease prevention and treatment. Topics discussed include the uses of plant and nutritional antioxidants in the contexts of reproductive health and prenatal development, healthcare and aging, noncommunicable chronic diseases, and environmental pollution. The text is complemented by a wealth of color figures and summary tables.

Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids

Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 530
Release: 2000-08-27
Genre: Medical
ISBN: 0309069491

This volume is the newest release in the authoritative series of quantitative estimates of nutrient intakes to be used for planning and assessing diets for healthy people. Dietary Reference Intakes (DRIs) is the newest framework for an expanded approach developed by U.S. and Canadian scientists. This book discusses in detail the role of vitamin C, vitamin E, selenium, and the carotenoids in human physiology and health. For each nutrient the committee presents what is known about how it functions in the human body, which factors may affect how it works, and how the nutrient may be related to chronic disease. Dietary Reference Intakes provides reference intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for different groups based on age and gender, along with a new reference intake, the Tolerable Upper Intake Level (UL), designed to assist an individual in knowing how much is "too much" of a nutrient.

Neurodegenerative Diseases

Neurodegenerative Diseases
Author: Shamim I. Ahmad
Publisher: Springer Science & Business Media
Total Pages: 421
Release: 2012-03-12
Genre: Medical
ISBN: 1461406536

The editor of this volume, having research interests in the field of ROS production and the damage to cellular systems, has identified a number of enzymes showing ·OH scavenging activities details of which are anticipated to be published in the near future as confirmatory experiments are awaited. It is hoped that the information presented in this book on NDs will stimulate both expert and novice researchers in the field with excellent overviews of the current status of research and pointers to future research goals. Clinicians, nurses as well as families and caregivers should also benefit from the material presented in handling and treating their specialised cases. Also the insights gained should be valuable for further understanding of the diseases at molecular levels and should lead to development of new biomarkers, novel diagnostic tools and more effective therapeutic drugs to treat the clinical problems raised by these devastating diseases.

Plant Antioxidants and Health

Plant Antioxidants and Health
Author: Halina Maria Ekiert
Publisher: Springer
Total Pages: 861
Release: 2022-06-26
Genre: Science
ISBN: 9783030781590

This book provides a comprehensive reference guide to plant-derived antioxidants, their beneficial effects, mechanisms of action, and role in disease prevention and improving general health (anti-ageing effect). The content is divided into three main parts, the first of which covers various antioxidants (such as polyphenols, carotenoids, tocopherols, tocotrienols, glutathione, ascorbic acid), their origins, plant biochemistry and industrial utilization. In turn, the book’s second, main part focuses on antioxidants’ beneficial health effects, explains biochemical fundamentals such as the free radical theory and oxidative stress, and discusses antioxidants’ role in e.g. cancer, cardiovascular diseases, inflammation, degenerative diseases and ageing. The third part reviews general laboratory methods for antioxidant screening, preservation and determination. Written by an international team of experts, this highly interdisciplinary book will benefit a broad range of health professionals and researchers working in biochemistry, biotechnology, nutrition, plant science and food chemistry. It offers an indispensable, up-to-date guide for anyone interested in antioxidants and the role of a plant-based diet in disease prevention and control

Nutrition and HIV

Nutrition and HIV
Author: Saurabh Mehta
Publisher: CRC Press
Total Pages: 326
Release: 2018-05-15
Genre: Medical
ISBN: 1351058185

The world continues to lose more than a million lives each year to the HIV epidemic, and nearly two million individuals were infected with HIV in 2017 alone. The new Sustainable Development Goals, adopted by countries of the United Nations in September 2015, include a commitment to end the AIDS epidemic by 2030. Considerable emphasis on prevention of new infections and treatment of those living with HIV will be needed to make this goal achievable. With nearly 37 million people now living with HIV, it is a communicable disease that behaves like a noncommunicable disease. Nutritional management is integral to comprehensive HIV care and treatment. Improved nutritional status and weight gain can increase recovery and strength of individuals living with HIV/AIDS, improve dietary diversity and caloric intake, and improve quality of life. This book highlights evidence-based research linking nutrition and HIV and identifies research gaps to inform the development of guidelines and policies for the United Nations’ Sustainable Development Goals. A comprehensive approach that includes nutritional interventions is likely to maximize the benefit of antiretroviral therapy in preventing HIV disease progression and other adverse outcomes in HIV-infected men and women. Modification of nutritional status has been shown to enhance the quality of life of those suffering HIV/AIDS, both physically in terms of improved body mass index and immunological markers, and psychologically, by improving symptoms of depression. While the primary focus for those infected should remain on antiretroviral treatment and increasing its availability and coverage, improvement of nutritional status plays a complementary role in the management of HIV infection.

Antioxidants and Disease Prevention

Antioxidants and Disease Prevention
Author: Harinder Garewal
Publisher: CRC Press
Total Pages: 210
Release: 2024-11-01
Genre: Medical
ISBN: 1040281621

The role of antioxidants and other nutritional agents in disease prevention is a widely discussed subject, attracting attention from professionals in all areas of medicine. This often-debated and rapidly evolving area of medicine could have important implications for how diseases are treated.

Plant-derived Bioactives

Plant-derived Bioactives
Author: Mallappa Kumara Swamy
Publisher: Springer Nature
Total Pages: 619
Release: 2020-05-11
Genre: Science
ISBN: 9811517614

Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs.

Free Radicals in Biology and Medicine

Free Radicals in Biology and Medicine
Author: Barry Halliwell
Publisher: Oxford University Press
Total Pages: 961
Release: 2015
Genre: Medical
ISBN: 0198717474

Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.