An Experimental And Molecular Analysis Of Pattern Formation In The Developing Vertebrate Limb
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Developmental Patterning of the Vertebrate Limb
Author | : J.Richard Hinchliffe |
Publisher | : Springer Science & Business Media |
Total Pages | : 434 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 1461533104 |
Following pioneering work by Harrison on amphibian limbs in the 1920s and by Saunders (1948) on the apical ridge in chick limbs, limb development became a classical model system for investigating such fundamental developmental issues as tissue interactions and induction, and the control of pattern formation. Earlier international conferences, at Grenoble 1972, Glasgow 1976,and Storrs, Connecticut 1982, reflected the interests and technology of their time. Grenoble was concerned with ectoderm-mesenchyme interaction, but by the time of the Glasgow meeting, the zone of polarizing activity (ZPA) and its role in control of patterning was the dominant theme. Storrs produced the first intimations that the ZPA could be mimicked by retinoic acid (RA), but the diversity of extracellular masrix ~olecules,particularly in skeletogenesis,was the main focus of attention. By 1990, the paradigms had again shifted. Originally, the planners of the ARW saw retinoic acid (as a possible morphogen controlling skeletal patterning), the variety of extracellular matrix components and their roles, and the developmental basis of limb evolution as the leading contemporary topics. However, as planning proceeded, it was clear that the new results emerging from the use of homeobox gene probes (first developed to investigate the genetic control of patterning of Drosophila embryos) to analyse the localised expression of "patterning genes" in limb buds would also be an important theme.
Experimental and Theoretical Advances in Biological Pattern Formation
Author | : Hans G. Othmer |
Publisher | : Springer Science & Business Media |
Total Pages | : 384 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 1461524334 |
This volume contains the proceedings of the NATO ARW on 'Biological Pattern Formation' held at Merton College, University of Oxford, on 27-31 August, 1992. The objective of the workshop was to bring together a select group of theoreticians and experimental biologists to present the latest results in the area of biological pattern formation and to foster interactiqn across dis- plines. The workshop was divided into 5 main areas: (i) limb development, (ii) Dictyostelium discoideum, (iii) Drosophila, (iv) cell movement, (v) g- eral pattern formation. We thank all the participants for their contributions, enthusiasm, and willingness to collaborate. There was a genuine, open, and extremely fru- ful interaction between the experimentalists and theoreticians which made the workshop a success. We also thank The Welcome Trust for providing additional funding. The local organization fell mainly on Denise McKittrick and Beverley Bhaskhare at the Mathematical Institute, Oxford, and Jeanette Hudson and the staff of Merton College. We greatly appreciate their help and patience. We also thank Jonathan Sherratt, Wendy Brandts and Debbie Benson for helping out in the conference and for providing a happy welcome to parti- pants on a typically cold, wet and windy English summer day.
Patterning in Vertebrate Development
Author | : Cheryll Tickle |
Publisher | : Frontiers in Molecular Biology |
Total Pages | : 272 |
Release | : 2003 |
Genre | : Language Arts & Disciplines |
ISBN | : 9780199638697 |
'Patterning in Vertebrate Development' is a new volume in the 'Frontiers in Molecular Biology' series which provides a range of comprehensive, and authoritative reviews of current research into patterning, a fundamental process in developmental biology.
Limb Development and Regeneration
Author | : John F. Fallon |
Publisher | : Wiley-Liss |
Total Pages | : 546 |
Release | : 1993-06-29 |
Genre | : Science |
ISBN | : |
This volume (in two parts) appears at a pivotal time for the study of pattern formation. The data from decades of experimental manipulation of the limb are now being used to help gain perspective and understanding on the explosion of descriptive information on the molecular biology of amniote development. These proceedings of the Fourth International Conference on Limb Development and Regeneration, held in Asilomar, California, July 1992, comprise 81 papers on such topics as the role of Hox genes in limb development; expression of homeobox genes in limb regeneration; why does a limb look like a limb?; lessons from extra digits, analysis of the mutant axolotl short toes; endothelial cell differentiation in the chick limb; in vitro mammalian limb differentiation as an experimental model; and retinoic acid and limb pattern formation. Parts A and B are not sold separately. Annotation c. by Book News, Inc., Portland, Or.
Vertebrate Pattern Formation
Author | : |
Publisher | : Elsevier |
Total Pages | : 458 |
Release | : 2024-06-01 |
Genre | : Science |
ISBN | : 0128234628 |
Vertebrate Pattern Formation, Volume 159 in the Current Topics in Developmental Biology series, highlights advances in the field, with this volume presenting interesting chapters on timely topics, including Hox genes patterning the vertebrate body, Endodermal patterning, The use of organoids/gastruloids to understand development, Cell shape and movements controlling development, Neural crest and placodes in vertebrate development, Patterning of the neural tube, Non-canonical Wnt signaling in axial extension, The control of transitions along the main body axis, Emergence of a left-right symmetric body plan in vertebrate embryos, Formation of the vascular system, Generation of patterns in the paraxial mesoderm, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series Updated release includes the latest information on the Vertebrate Pattern Formation
Vertebrate Limb and Somite Morphogenesis
Author | : British Society for Developmental Biology |
Publisher | : |
Total Pages | : 498 |
Release | : 1977 |
Genre | : Chickens |
ISBN | : |
Biological Physics of the Developing Embryo
Author | : Gabor Forgacs |
Publisher | : Cambridge University Press |
Total Pages | : 346 |
Release | : 2005-11-24 |
Genre | : Science |
ISBN | : 9780521783378 |
During development cells and tissues undergo changes in pattern and form that employ a wider range of physical mechanisms than at any other time in an organism's life. This book demonstrates how physics can be used to analyze these biological phenomena. Written to be accessible to both biologists and physicists, major stages and components of the biological development process are introduced and then analyzed from the viewpoint of physics. The presentation of physical models requires no mathematics beyond basic calculus.
HOX Gene Expression
Author | : Spyros Papageorgiou |
Publisher | : Springer Science & Business Media |
Total Pages | : 158 |
Release | : 2007-08-28 |
Genre | : Medical |
ISBN | : 0387689907 |
Hox Gene Expression starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. It deals with homeotic genes, their evolution, structure, normal and abnormal function. Researchers and graduate students in biology and medicine will benefit from this integrated overview of Hox gene activities.
The Development of the Vertebrate Limb
Author | : J. R. Hinchliffe |
Publisher | : Oxford University Press, USA |
Total Pages | : 306 |
Release | : 1980 |
Genre | : Biography & Autobiography |
ISBN | : |