Apicomplexan Parasites

Apicomplexan Parasites
Author: Katja Becker
Publisher: John Wiley & Sons
Total Pages: 548
Release: 2011-01-19
Genre: Medical
ISBN: 3527633901

This handbook is the first dealing with the discovery of drugs directed against apicomplexan parasites. Amongst others, this group of endoparasites includes the causative agents of Malaria, Toxoplasmosis, and Babesiosis, the latter occurring mainly in animals. Written by renowned scientific experts from academia and industry, the book focuses on currentdrug development approaches for all apicomplexan diseases making it appealing to a large audience, ranging from research labs in academia to the human and veterinarian pharmaceutical industry. This work is the second volume of the new book series 'Drug Discovery in Infectious Diseases', edited by Prof. Dr Paul M. Selzer.

Malaria

Malaria
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 312
Release: 1991-02-01
Genre: Medical
ISBN: 9780309045278

Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

Falciparum Malaria

Falciparum Malaria
Author: Tabish Qidwai
Publisher: Elsevier
Total Pages: 238
Release: 2024-04-14
Genre: Medical
ISBN: 0323957838

Falciparum Malaria: Diagnostic Tools, Therapeutic Advances, and Future Opportunities discusses the current state of therapeutic options for malaria, antimalarial drugs and drug targets. The book also covers recent progress in the development of vaccines and other approaches for malaria treatment, prevention and control and explores diagnostic tools and biomarkers. Sections examine potential biomarkers and their applications, molecular diagnostic tools, multi-omic approaches for the characterization of therapeutic action of potential new antimalarials, therapeutic advances in falciparum malaria, antimalarial drugs, targeting parasite apicoplast for antimalarial drug discovery, cellular and adjunctive therapies for malaria treatment, and future opportunities. With contributions from experts in the field, this book is an ideal resource for academics, researchers, graduates and industry engaged in malaria research, its diagnosis, and treatment. - Reviews current therapeutic strategies of falciparum malaria - Covers antimalarial drugs, peptides, vaccines and RNAi approaches against malaria - Explores antimalarial drug targets in parasites - Discusses biomarkers and new diagnostic tools

Travel Medicine E- Book

Travel Medicine E- Book
Author: Phyllis Kozarsky
Publisher: Elsevier Health Sciences
Total Pages: 1827
Release: 2008-06-06
Genre: Medical
ISBN: 0323070566

The second edition of this popular text features a team of international experts who discuss all aspects of travel medicine-from immunizations and pre-travel advice for adults and children...to the latest information on cruise travel, bird flu, and SARS...to the essentials of post-travel screening. It reflects current ‘best practices’ and remains both the leading comprehensive reference text on the principles and practice of travel medicine and a rich resource of practical guidance that you can use daily. And, as an Expert Consult title, this thoroughly updated second edition comes with access to the complete contents online, fully searchable-enabling you to consult it rapidly from any computer with an Internet connection. Discusses common travel illnesses, including traveler’s diarrhea and malaria to help you treat whatever you see. Addresses environmental problems such as altitude sickness, extremes in temperatures, and sun exposure to help your patients prepare for high-risk activites in extreme environments. Offers advice on establishing and running a travel clinic. Provides access to the complete contents online, fully searchable, enabling you to consult it rapidly from any computer with an Internet connection. Features revised chapters to reflect current best practices as well as completely updated chapters, keeping you abreast of this rapidly changing field. Presents a new chapter on cruise travel to help you provide complete travel medicine advice. Provides cross references for the ISTM “body of knowledge? to specific chapters and/or passages in the book to help you prepare for the ISTM travel medicine examination. Uses a new logical organization that speeds you to the information you need. Provides cross references for the ISTM “body of knowledge? to specific chapters and/or passages in the book to help you prepare for the ISTM travel medicine examination.

Biotechnological Advances for Microbiology, Molecular Biology, and Nanotechnology

Biotechnological Advances for Microbiology, Molecular Biology, and Nanotechnology
Author: Jyoti Ranjan Rout
Publisher: CRC Press
Total Pages: 741
Release: 2022-04-27
Genre: Science
ISBN: 1000369447

Biotechnological Advances for Microbiology, Molecular Biology, and Nanotechnology: An Interdisciplinary Approach to the Life Sciences presents cutting-edge research associated with the beneficial implications of biotechnology on human welfare. The volume mainly focuses on the highly demanding thrust areas of biotechnology that are microbiology, molecular biology, and nanotechnology. The book provides a detailed overview of the beneficial roles of microbes and nanotechnology-based engineered particles in biological developments. Also, it highlights the role of epigenetic machinery and redox modulators during the development of diseases. In addition, it provides research on nanotechnology-based applications in tissue engineering, stem cell, and regenerative medicines. Overall, the book provides an extended platform for acquiring the methodological knowledge needed for today’s biotechnological applications, such as DNA methylation, redox homeostasis, CRISPR, nano-based drug delivery systems, proteomics, genomics, metagenomics, bioluminescence, bioreactors, bioremediation, biosensors, etc. Divided into three sections, the book first highlights some recent trends in applied microbiology used in different areas, such as crop improvement, wastewater treatment, drug delivery, healthcare management, and more. The volume goes on to cover some advances in cellular and molecular mechanisms, such as CRISPR technology in biological systems, induced stem cells in disease prevention, integrated omics technology, and others. The volume also explores the indispensable role of nanotechnology in the precisely modulating intricate functioning of an organism in diagnostic and therapy along its application in tissue engineering and regenerative medicine and in food science as well as its role in ecological sustainability. This multidisciplinary volume will be highly valuable for the researchers, scientists, biologists, and faculty and students striving to expand their horizon of knowledge in their respective fields.

Comprehensive Analysis of Parasite Biology

Comprehensive Analysis of Parasite Biology
Author: Sylke Müller
Publisher: John Wiley & Sons
Total Pages: 574
Release: 2016-10-10
Genre: Medical
ISBN: 3527339043

Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art "omics" technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented.