Aldol Reactions

Aldol Reactions
Author: Rainer Mahrwald
Publisher: Springer Science & Business Media
Total Pages: 214
Release: 2009-05-15
Genre: Science
ISBN: 1402087012

Aldol Reactions provides a comprehensive up-to-date overview of aldol reactions including application of different metal enolates; catalytic aldol additions catalyzed by different Lewis acids and Lewis bases; enantioselective direct aldol additions; antibodies and enzyme catalyzed aldol additions and the recent aggressive development of organocatalyzed aldol additions. The power of each method is demonstrated by several applications in total synthesis of natural products. The pros and cons of these methodologies with regard to stereoselectivity, regioselectivity and application in total synthesis of natural products are discussed. Great importance is set to the diverse possibilities of the manual of aldol reaction to install required configurations in complicated natural product synthesis.

Modern Methods in Stereoselective Aldol Reactions

Modern Methods in Stereoselective Aldol Reactions
Author: Rainer Mahrwald
Publisher: John Wiley & Sons
Total Pages: 604
Release: 2013-02-22
Genre: Science
ISBN: 3527656731

The selective formation of bondings between molecules is one of the major challenges in organic chemistry, and the so-called aldol reaction is one of the most important for this purpose. These reactions are a highly useful tool for developing such novel substances as natural products and pharmaceuticals. Likes its highly successful and much appreciated predecessor, "Modern Aldol Reactions", this ready reference provides a systematic overview of methodologies for installing a required configuration during an aldol addition step, but shifts the focus so as to cover the latest developments. As such, it presents a set of brand new tools, including vinylogous Mukaiyama-aldol reactions and substrate-controlled aldol reactions, as well as asymmetric induction in aldol additions. Furthermore, new developments in existing stereoselective aldol additions are described, such as the deployment of supersilyl groups or organocatalyzed aldol additions. All of these methodologies are presented in the context of their deployment in the total synthesis of natural products.

Name Reactions

Name Reactions
Author: Jie Jack Li
Publisher: Springer Science & Business Media
Total Pages: 670
Release: 2007-02-16
Genre: Science
ISBN: 3540300317

This book differs from others on name reactions in organic chemistry by focusing on their mechanisms. It covers over 300 classical as well as contemporary name reactions. Biographical sketches for the chemists who discovered or developed those name reactions have been included. Each reaction is delineated by its detailed step-by-step, electron-pushing mechanism, supplemented with the original and the latest references, especially review articles. This book contains major improvements over the previous edition and the subject index is significantly expanded.

Name Reactions

Name Reactions
Author: Jie Jack Li
Publisher: Springer Science & Business Media
Total Pages: 704
Release: 2014-01-30
Genre: Science
ISBN: 3319039792

In this fifth edition of Jack Jie Li's seminal "Name Reactions", the author has added twenty-seven new name reactions to reflect the recent advances in organic chemistry. As in previous editions, each reaction is delineated by its detailed step-by-step, electron-pushing mechanism and supplemented with the original and the latest references, especially from review articles. Now with addition of many synthetic applications, this book is not only an indispensable resource for advanced undergraduate and graduate students, but is also a good reference book for all organic chemists in both industry and academia. Unlike other books on name reactions in organic chemistry, Name Reactions, A Collection of Detailed Reaction Mechanisms and Synthetic Applications focuses on the reaction mechanisms. It covers over 320 classical as well as contemporary name reactions.

Named Organic Reactions

Named Organic Reactions
Author: Thomas Laue
Publisher: John Wiley & Sons
Total Pages: 320
Release: 2005-08-19
Genre: Science
ISBN: 0470026448

This Second edition contains consise information on 134 carefully chosen named organic reactions - the standard set of undergraduate and graduate synthetic organic chemistry courses. Each reaction is detailed with clearly drawn mechanisms, references from the primary literature, and well-written accounts covering the mechanical aspects of the reactions, and the details of side reactions and substrate limitations. For the 2nd edition the complete text has been revised and updated, and four new reactions have been added: Baylis-Hillmann Reaction, Sonogashira Reaction, Pummerer Reaction, and the Swern Oxidation und Cyclopropanation. An essential text for students preparing for exams in organic chemistry.

Modern Aldol Reactions, 2 Volume Set

Modern Aldol Reactions, 2 Volume Set
Author: Rainer Mahrwald
Publisher: John Wiley & Sons
Total Pages: 759
Release: 2004-08-06
Genre: Science
ISBN: 3527307141

At long last, the complete spectrum of the aldol reaction is presented here in this two-volume handbook. Top authors guarantee contributions of the highest quality, beginning with fundamentals and then moving on to enolates and catalytic aldol reactions, including the Mukaiyama Reaction. Further sections are devoted to enzymatic aldol reactions in synthesis as well as such related reactions as the Henry, Ene and Aldol-Tishchenko reactions. The wealth of information contained here allows a comprehensive overview of this important topic in organic chemistry, removing the need for the hitherto time-consuming research among the widely dispersed literature. With a foreword by Professor D. A. Evans.

Advanced Organic Chemistry

Advanced Organic Chemistry
Author: Francis A. Carey
Publisher: Springer Science & Business Media
Total Pages: 1344
Release: 2007-09-06
Genre: Medical
ISBN: 038768350X

The two-part, fifth edition of Advanced Organic Chemistry has been substantially revised and reorganized for greater clarity. The material has been updated to reflect advances in the field since the previous edition, especially in computational chemistry. Part B describes the most general and useful synthetic reactions, organized on the basis of reaction type. It can stand-alone; together, with Part A: Structure and Mechanisms, the two volumes provide a comprehensive foundation for the study in organic chemistry. Companion websites provide digital models for students and exercise solutions for instructors.

Microbial Transformations of Steroids

Microbial Transformations of Steroids
Author: William Charney
Publisher: Academic Press
Total Pages: 743
Release: 2014-06-28
Genre: Science
ISBN: 1483261557

Microbial Transformations of Steroids: A Handbook aims to provide those who wish to use microbial transformations of steroids with a single source book starting from 1937 to the present. The handbook first offers information on the history of the microbial transformations of organic compounds, including earliest works on the study of nonsteroids and steroids; significance of discovery of anti-inflammatory action of cortisone; first hydroxylations and dehydrogenations; manufacture of natural and synthetic corticosteroids; and trends in research. The text then ponders on chemical classification of microbial transformations of steroids, as well as the role of enzymes in microbial transformations and the classes of reactions. The publication elaborates on the construction and use of the table. Topics include order of the table, nomenclature, description of the transformation leading to the product, yield, organism, and constants. The book also focuses on taxonomy and use of the table, including system of classification, specific notes on divisions of the table, and source of cultures. The handbook is a valuable source of data for readers interested in the microbial transformations of steroids.

Tandem Organic Reactions

Tandem Organic Reactions
Author: Tse-Lok Ho
Publisher: John Wiley & Sons
Total Pages: 516
Release: 1992-08-17
Genre: Science
ISBN: 9780471570226

The importance of tandem reactions is evident--besides their pragmatic value, they have an aesthetic appeal. The author presents a survey of these reactions that will rivet the attention of numerous chemists to their merits and utility as well as stimulate design and discovery of new sets of tandem reactions. Coverage includes Aldol condensation, Michael Reaction, Dieckmann cyclization, thermal and free radical processes, stitching reactions and much more.