Advances in Swine in Biomedical Research

Advances in Swine in Biomedical Research
Author: L.B. Schook
Publisher: Springer Science & Business Media
Total Pages: 482
Release: 1997-01-31
Genre: Medical
ISBN: 9780306454950

Contains papers from the October 1995 symposium, in sections on general aspects, transgenics, and immunology and infectious diseases. Topics include ultrastructure of the liver in piglets fed dietary oils, artificial surfactant as a vehicle for endotracheal epinephrine in pediatric porcine cardiopulmonary arrest, transplantation and genetic manipulation in porcine systems, assessment of public health aspects of porcine xenotransplantation, cellular immune responses controlling infectious diseases, and associations between stress- susceptibility and immune status in pigs. Annotation copyrighted by Book News, Inc., Portland, OR

Advances in Swine in Biomedical Research

Advances in Swine in Biomedical Research
Author: Mike E. Tumbleson
Publisher: Springer Science & Business Media
Total Pages: 510
Release: 1996
Genre: Medical
ISBN: 9780306454967

Contains papers from the October 1995 symposium, in sections on methods and techniques, and nutrition. Subjects include the Yucatan miniature pig model of ventricular septal defect, the minipig as a model for the study of aging in humans, an external thoracic duct venous shunt to allow for long-term

Sourcebook of Models for Biomedical Research

Sourcebook of Models for Biomedical Research
Author: P. Michael Conn
Publisher: Springer Science & Business Media
Total Pages: 756
Release: 2008
Genre: Medical
ISBN: 1588299333

The collection of systems represented in Sourcebook of genomic programs, although this work is certainly well Models for Biomedical Research is an effort to re?ect the represented and indexed. diversity and utility of models that are used in biomedicine. Some models have been omitted due to page limitations That utility is based on the consideration that observations and we have encouraged the authors to use tables and made in particular organisms will provide insight into the ? gures to make comparisons of models so that observations workings of other, more complex, systems. Even the cell not available in primary publications can become useful to cycle in the simple yeast cell has similarities to that in the reader. humans and regulation with similar proteins occurs. We thank Richard Lansing and the staff at Humana for Some models have the advantage that the reproductive, guidance through the publication process. mitotic, development or aging cycles are rapid compared As this book was entering production, we learned of the with those in humans; others are utilized because individual loss of Tom Lanigan, Sr. Tom was a leader and innovator proteins may be studied in an advantageous way and that in scienti?c publishing and a good friend and colleague to have human homologs. Other organisms are facile to grow all in the exploratory enterprise. We dedicate this book to in laboratory settings or lend themselves to convenient analy- his memory. We will miss him greatly.

Critical Needs for Research in Veterinary Science

Critical Needs for Research in Veterinary Science
Author: National Research Council
Publisher: National Academies Press
Total Pages: 238
Release: 2005-10-18
Genre: Technology & Engineering
ISBN: 0309164982

Research in veterinary science is critical for the health and well-being of animals, including humans. Food safety, emerging infectious diseases, the development of new therapies, and the possibility of bioterrorism are examples of issues addressed by veterinary science that have an impact on both human and animal health. However, there is a lack of scientists engaged in veterinary research. Too few veterinarians pursue research careers, and there is a shortage of facilities and funding for conducting research. This report identifies questions and issues that veterinary research can help to address, and discusses the scientific expertise and infrastructure needed to meet the most critical research needs. The report finds that there is an urgent need to provide adequate resources for investigators, training programs, and facilities involved in veterinary research.

Advances in Swine in Biomedical Research

Advances in Swine in Biomedical Research
Author: L.B. Schook
Publisher: Springer Science & Business Media
Total Pages: 510
Release: 2013-03-07
Genre: Medical
ISBN: 1461558859

Similarities in structure and function between pigs and human beings include size, feeding patterns, digestive physiology, dietary habits, kidney structure and function, pulmo nary vascular bed structure, coronary artery distribution, propensity to obesity, respiratory rates, tidal volumes and social behaviors. Since the pig is an omnivore, it provides an adaptable model to evaluate chronic and acute exposures to xenobiotics such as alcohoL caffeine, tobacco, food additives and environmental pollutants. Swine have been used successfully as models to evaluate alcoholism, diabetes, absorption, digestion, total paren teral nutrition, organ transplantation, atherosclerosis, exercise, hypertension. hemorrhagic hypotension, melanoma, gingivitis, obstructive and reflux nephropathy. osteochondrosis. dermal healing and septic shock. A severe and worsening shortage of organs and tissues for transplantation in patients with severe organ failure has encouraged the consideration of inter species or xenotransplan tation. In developing programs toward this end, the pig generally is viewed as the preferred donor because of its size, physiology and availability. The pig harbors relatively few diseases which could be transmitted inadvertently to human patients. The ability to genetically modify swine to ameliorate the consequences of the human immune response offers a further significant advantage. Another important consideration for an animal model is that basic biologic back ground information be available for investigators to design future prospective studies.

Using Animal Models in Biomedical Research

Using Animal Models in Biomedical Research
Author: Pierce K. H. Chow
Publisher: World Scientific
Total Pages: 309
Release: 2008
Genre: Medical
ISBN: 9812812024

Ch. 1. Scientific considerations and choice of species. ch. 1.1. The rationale for the use of animal models in biomedical research / Pierce Chow. ch. 1.2. Experimental animal models in biomedical resarch / Robert Ng. ch. 1.3. Nonhuman primates as models in biomedical research / Jason Vilano and Bryan Ogden -- ch. 2. Regulatory considerations in the use of animal models. ch. 2.1. Laws, regulations and guidelines for biomedical research in Singapore / Boon Theng Kuah. ch. 2.2. The functions of the institutional animal care and use committee / Pierce Chow. ch. 2.3. Responsibilities of principal investigators and research protocol evaluation / Hock Soo Ong. ch. 2.4. The 3R's, research variables and the use of alternatives / Hock Soo Ong. ch. 2.5. Use of statistics as determinant for number of animals used / Huihua Li. ch. 2.6. The advantages of accreditation with AAALAC / Bryan Ogden -- ch. 3. Animal handling and surgical procedures. ch. 3.1. General handling, restraint, oral dosing/gavage and injections in laboratory animals / Bryan Ogden. ch. 3.2. Blood collection from laboratory animals / Jason Villano. ch. 3.3. Antibiotic coverage and therapy / Darvi Sergio. ch. 3.4. Animal preparation and transport / Robert Ng. ch. 3.5. Preparation and implementation of animal surgery / Robert Ng. ch. 3.6. Animal intubation / Robert Ng. ch. 3.7. Anaesthesia and maintenance of homeostasis / Robert Ng. ch. 3.8. Animal euthanasia / Darvi Sergio. ch. 3.9. Rodent sentinel programme / Peik Khin Tan -- ch. 4. Basic animal investigative methods. ch. 4.1. Bioimaging in animals / David Ng [und weitere]. ch. 4.2. Histology sampling and techniques / In Chin Song. ch. 4.3. Animal tissue perfusion and preservation / Robert Ng. ch. 4.4. Animal cell culture / Kai Zhang and Peggy Yong. ch. 4.5. Application of microsurgical techniques in animal research / Bien Keem Tan [und weitere] -- ch. 5. Animal welfare considerations. ch. 5.1. Species specific caging configuration and design / Cindy Phua. ch. 5.2. Postoperative care and pain management / Jason Villano. ch. 5.3. Animal feeds and nutritional requirements / Peik Khin Tan -- ch. 6. Safety management of an animal facility. ch. 6.1. Occupational health and safety programme / Angela Goh. ch. 6.2. New employee and external users orientation / Inria Kurniawan Then. ch. 6.3. Radiation safety awareness in animal research / S. Somanesan. ch. 6.4. Emergency crisis management / Irene Kee. ch. 6.5. Zoonoses and laboratory animal allergies / Jason Villano -- ch. 7. Supporting facilities design. ch. 7.1. Clinical skills laboratory / Robert Ng. ch. 7.2. Animal research supporting laboratories / Robert Ng. ch. 7.3. Animal research and housing facilities / Robert Ng -- ch. 8. The development of comprehensive animal facilities in Singapore. ch. 8.1. History of the Department of Experimental Surgery as a reflection of translational research development in Singapore / Robert Ng

Use of Laboratory Animals in Biomedical and Behavioral Research

Use of Laboratory Animals in Biomedical and Behavioral Research
Author: National Research Council
Publisher: National Academies Press
Total Pages: 113
Release: 1988-02-01
Genre: Science
ISBN: 0309038391

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Swine Nutrition

Swine Nutrition
Author: Austin J. Lewis
Publisher: CRC Press
Total Pages: 1030
Release: 2000-12-21
Genre: Nature
ISBN: 1420041843

With 42 chapters authored by leading international experts, Swine Nutrition: Second Edition is a comprehensive reference that covers all aspects of the nutrition of pigs. Content includes characteristics of swine and the swine industry with emphasis on the gastrointestinal tract; various classes of nutrients, how these nutrients are metabolized by swine, and the factors affecting their utilization; the practical aspects of swine nutrition from birth through gestation, lactation in sows, and the feeding of adult boars; and nutritional aspects of the various feedstuffs commonly fed to swine. Rounding the book is coverage of various techniques used in swine nutrition research.