Advances In Alzheimers Research
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Author | : Jeffrey Cummings |
Publisher | : Cambridge University Press |
Total Pages | : 575 |
Release | : 2022-03-31 |
Genre | : Business & Economics |
ISBN | : 1108838669 |
Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Author | : Ahmed Moustafa |
Publisher | : Academic Press |
Total Pages | : 256 |
Release | : 2021-08-28 |
Genre | : Psychology |
ISBN | : 0128213353 |
Nearly 44 million people have Alzheimer's or related dementia worldwide, according to the Alzheimer's Disease International organization. That number is expected to double every 20 years. Unlike other books on the market, Alzheimer's Disease: Understanding Biomarkers, Big Data, and Therapy covers recent advancements in cognitive, clinical, neural, and therapeutic aspects of Alzheimer's and other forms of dementia.First, readers are introduced to cognitive and clinical studies, focusing on the different types of memory impairment, past and future thinking. This includes the prevalence of depression, its relationship to other symptoms, and the quality of life for those with Alzheimer's disease. In addition, the book discusses recent studies on memory dysfunction in advanced-stage Alzheimer's disease, in comparison to early-stage, including a chapter on the underlying factors in the transition from mild cognitive impairment to Alzheimer's diagnosis. Following this section, the book presents recent studies on the role of different cortical and subcortical structures in the development of various symptoms in Alzheimer's disease, as well as different neural biomarkers underlying the development and treatment of the disease. In the last section of the book, therapeutic aspects of Alzheimer's disease, focusing on behavioral and pharmacological treatments of sleep disorders, memory problems, and depression, are reviewed. The book aids readers in understanding the advances in research and care, making it a prime tool for all clinicians, psychologists, researchers, neurologists, and caregivers of dementia patients. - Reviews recent developments of cognitive and clinical studies - Covers factors underlying the transition from mild cognitive impairment to Alzheimer's disease - Discusses different neural biomarkers underlying the development and treatment of Alzheimer's disease - Provides a comparison of the effectiveness of various types of treatments
Author | : National Academies of Sciences Engineering and Medicine |
Publisher | : |
Total Pages | : |
Release | : 2022-04-26 |
Genre | : |
ISBN | : 9780309495035 |
As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.
Author | : Elias K. Michaelis |
Publisher | : Academic Press |
Total Pages | : 400 |
Release | : 2012-08-02 |
Genre | : Medical |
ISBN | : 0123948169 |
"Providing a cross-section of current research, treatments and potential clinical developments, this volume of Advances in Pharmacology is an essential resource for biologists, pharmacologists and those engaged with Alzheimer's research."--P. [4] of cover.
Author | : George Perry |
Publisher | : IOS Press |
Total Pages | : 486 |
Release | : 2013 |
Genre | : Medical |
ISBN | : 1614991537 |
This volume is a companion to the highly successful book published in association with the Journal of Alzheimer's Disease (JAD) on the centennial of Alzheimer's discovery: "Alzheimer's Disease: A Century of Scientific and Clinical Research". Instead of looking back, this collection, "Alzheimer's Disease: Advances for a New Century", will look forward. Using scientometric analysis the most promising developments since the Alzheimer Centennial in 2006 have been substantiated. While prior trends and advances in genetics, amyloid-β, tau, neuropathology, and oxidative stress continue as active areas, emergent areas impacting the transition from normal cognition to Alzheimer's disease such as diagnostic imaging, biomarkers, metabolism, and lifestyle (areas conceived only a few years ago) now dominate the debate.Invited contributors have summarized their landmark publications identified by our analysis and have put them into perspective, explaining the impetus behind the work, the contribution of the results to the field, and who played a role in the work.
Author | : Khalid Iqbal |
Publisher | : John Wiley & Sons |
Total Pages | : 900 |
Release | : 2001 |
Genre | : Medical |
ISBN | : |
Alzheimer's Disease is an ever-present problem affecting millions of people around the world and, as people's average lifespan lengthens, its prevalence is set to increase. A global effort is needed to combat the disease, including research to investigate the causes, development of effective treatments and, ultimately, prevention of the disease. Published every two years, these timely books discuss the very latest research. This new volume in the series: Provides a uniques source of reference to the important work being done in this field Gives academics and clinicians an opportunity to learn about cutting edge developments Covers all aspects of Alzheimer's Disease, including diagnosis, clinical course, epidemiological course and therapeutics and disease mechanisms. Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics and Therapeutics will provide essential information for basic and clinical researchers in Alzheimer's Disease and other dementias as well as for those who care for patients.
Author | : Blas Gil-Extremera |
Publisher | : Bentham Science Publishers |
Total Pages | : 191 |
Release | : 2019-04-03 |
Genre | : Medical |
ISBN | : 9811405123 |
Alzheimer's disease is the most frequent cause of dementia that slowly and progressively causes cognitive impairment and profoundly alters the daily activities of the patients. Approximately, ten percent of all persons over the age of seventy experience significant memory loss, and in more than half of the cases, the cause is Alzheimer's disease. This reference book is an update on the most relevant pathological and clinical findings of this neurological disorder. Chapters cover the basic hypothesis of Alzheimer’s disease, pathological features of the disease in the brain, Alzheimer’s disease diagnosis and therapy. Information provided in the book is focused on research in developed countries. The book offers students of medicine and nursing as well as medical practitioners and specialists (internists, neurologists, gerontologists, and psychiatrists), the necessary information to understand the pathological and clinical aspects of the disease in depth, with the goal of improving medical outcomes in the care of their patients.
Author | : George Perry |
Publisher | : IOS Press |
Total Pages | : 478 |
Release | : 2006 |
Genre | : Medical |
ISBN | : 9781586036195 |
"This is the book edition of the Journal of Alzheimer's Disease, Volume 9, No.3 Supplement (2006)"--T.p. verso.
Author | : Jennifer R. Stelter |
Publisher | : JHU Press |
Total Pages | : 193 |
Release | : 2021-10-19 |
Genre | : Family & Relationships |
ISBN | : 1421441071 |
"The Dementia Connection Model is a recipe to connect families in a way that produces positive interactions and preserves their loved one's level of functioning for as long as possible. The model brings together three concepts in dementia care of what is happening to the person with Alzheimer disease and, more importantly, why these things are happening as the person's condition progresses and how to intervene successfully"--
Author | : Sangram S. Sisodia |
Publisher | : Springer |
Total Pages | : 0 |
Release | : 2010-10-29 |
Genre | : Medical |
ISBN | : 9781441941954 |
This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.