Advanced Nanoformulations

Advanced Nanoformulations
Author: Md Saquib Hasnain
Publisher: Academic Press
Total Pages: 873
Release: 2023-03-24
Genre: Medical
ISBN: 0323885799

Advanced Nanoformulations: Theranostic Nanosystems, Volume Three examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications. - Contains in-depth discussions of the advanced formulations using nanosystems including high-quality graphics, flowcharts, and graphs for enhanced understanding - Reviews the literature on advanced formulations while also suggesting new avenues - Includes contributions in all areas of advanced formulations, providing a thorough and interdisciplinary work

Nanoparticle Therapeutics

Nanoparticle Therapeutics
Author: Prashant Kesharwani
Publisher: Academic Press
Total Pages: 674
Release: 2021-11-06
Genre: Technology & Engineering
ISBN: 0128209186

Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states. This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful. Brings together the novel applications of nanotechnology in biological fields Explores perspectives on technologies through highly organized tables, illustrative figures and flow charts Addresses key multidisciplinary challenges faced by nanotechnologists to foster collaboration among biologists, chemists, physicists, engineers and clinicians

Advanced Drug Delivery Systems in the Management of Cancer

Advanced Drug Delivery Systems in the Management of Cancer
Author: Kamal Dua
Publisher: Elsevier
Total Pages: 572
Release: 2021-06-24
Genre: Business & Economics
ISBN: 0323900798

Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems

Advanced Functional Nanoparticles "Boon or Bane" for Environment Remediation Applications

Advanced Functional Nanoparticles
Author: Raman Kumar
Publisher: Springer Nature
Total Pages: 372
Release: 2023-06-18
Genre: Technology & Engineering
ISBN: 3031244168

This textbook provides an overview of applications of advanced nanomaterials, basic lab set up and requirements in for their synthesis, techniques and career scope of nanotechnology in industries and research. Pollution of air, water, soil is an ever increasing environmental problem attributed to increasing population, global industrialization and unplanned urbanization, has acquired alarming dimensions. It is the most dangerous and worst problem that puts the lives of people, animals, and plants on the earth in danger. An effective, efficient and sustainable approach for managing pollution related problems requires the utmost attention of the scientific community to tackle this menace for the society to lead a healthy and quality life. A number of techniques and books, literatures have been developed in recent years to treat environmental contaminants. However, most of these are not economically viable, environmentally benign and suffer due to cumbersome multi-step manipulations. The purpose of this textbook is to inform students about the application of functionalized nanoparticles as a new approach to supplement traditional treatment methods in cost and time effective manner. The simplistic means to assemble nanoparticles to the constituents of next generation technologies in environment cleanup and sensing are the main objectives of the book. The toxicological footprinting of released advanced functional nanomaterials in ecosystem will also be discussed in the book.

Nanoformulation Strategies for Cancer Treatment

Nanoformulation Strategies for Cancer Treatment
Author: Sarwar Beg
Publisher: Elsevier
Total Pages: 403
Release: 2020-11-20
Genre: Technology & Engineering
ISBN: 0128210966

Nanoformulation Strategies for Cancer Treatment provides an up-to-date review on current developments and regulatory and clinical challenges in the field of nanopharmaceuticals and the effective treatment of diverse varieties of cancer. This important reference source is ideal for biomaterials scientists and pharmaceutical scientists working in the area of cancer diagnosis and therapy. Due to the high cost of traditional cancer treatment types, researchers have increasingly looked for new ways to augment the therapeutic performance of existing drug candidates. The use of nanotechnology-based approaches have gained significant momentum, thus leading to the launch of a series of new drug products. As nanopharmaceuticals improve the therapeutic performance of cancer therapy drugs, but also provide opportunities for site-specific drug targeting in tumors, this work is a welcomed resource on the topics discussed. - Highlights the application of nanoformulations, including liposomes, nanoparticles and nanobiomaterials for targeted drug delivery to cancer cells - Explores recent advances made using novel nanoformulations containing herbal drugs and biotechnology based therapeutic strategies for cancer treatment - Assesses the regulatory hurdles that are necessary for the successful clinical translation of nanomedicines from the laboratory into the market

Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems

Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems
Author: Jayvadan K. Patel
Publisher: Springer Nature
Total Pages: 437
Release: 2022-03-07
Genre: Science
ISBN: 303083395X

A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not easily metabolized or that obtain the desired therapeutic effect with minimum toxicity. The authors provide an overview of biodistribution with a focus on polymer and lipid nanoparticles. This thorough reference is divided into three parts: Modelling, Specific carries and their potential to treat specific diseases.

Nanopharmaceutical Advanced Delivery Systems

Nanopharmaceutical Advanced Delivery Systems
Author: Vivek Dave
Publisher: John Wiley & Sons
Total Pages: 467
Release: 2020-12-29
Genre: Computers
ISBN: 1119711681

The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.

Cutting-Edge Applications of Nanomaterials in Biomedical Sciences

Cutting-Edge Applications of Nanomaterials in Biomedical Sciences
Author: Prabhakar, Pranav Kumar
Publisher: IGI Global
Total Pages: 631
Release: 2024-01-04
Genre: Technology & Engineering
ISBN:

Cutting-Edge Applications of Nanomaterials in Biomedical Sciences is a comprehensive exploration of the revolutionary impact of nanotechnology on the field of medicine. This book delves into the remarkable potential of nanomaterials in advancing medical diagnostics and therapeutics, particularly in drug delivery. It serves as an indispensable guide, presenting the latest developments in nanomedicine, precision medicine, and nanoengineering while addressing the challenges and opportunities that arise. The book covers a wide range of topics, from nanomaterials for cancer therapy to their applications in imaging and diagnostics. It discusses the transformative role of nanomaterials in targeted delivery and controlled release, as well as their potential in regenerative medicine and infectious disease diagnosis and treatment. By presenting cutting-edge research and developments in the field, this book aims to bridge the gap between bench and bedside, providing a vital resource for researchers, clinicians, and students in the biomedical sciences. Moreover, it highlights the commercialization potential of nanomedicine, fostering collaboration between academia and industry. Policymakers and regulators will also find this book invaluable for understanding the ethical and safety implications of incorporating nanomaterials into medical practices.

Nanotechnology in Medicine

Nanotechnology in Medicine
Author: Mahendra Rai
Publisher: John Wiley & Sons
Total Pages: 452
Release: 2021-10-25
Genre: Science
ISBN: 1119769868

NANOTECHNOLOGY IN MEDICINE Discover thorough insights into the toxicology of nanomaterials used in medicine In Nanotechnology in Medicine: Toxicity and Safety, an expert team of nanotechnologists delivers a robust and up-to-date review of current and future applications of nanotechnology in medicine with a special focus on neurodegenerative diseases, cancer, diagnostics, nano-nutraceuticals, dermatology, and gene therapy. The editors offer resources that address nanomaterial safety, which tends to be the greatest hurdle to obtaining the benefits of nanomedicine in healthcare. The book is a one-stop resource for recent and comprehensive information on the toxico logical and safety aspects of nanotechnology used in human health and medicine. It provides readers with cutting-edge techniques for delivering therapeutic agents into targeted cellular compartments, cells, tissues, and organs by using nanoparticulate carriers. The book also offers methodological considerations for toxicity, safety, and risk assessment. Nanotechnology in Medicine: Toxicity and Safety also provides readers with: A thorough introduction to the nanotoxicological aspects of nanomedicine, including translational nanomedicine and nanomedicine personalization Comprehensive introductions to nanoparticle toxicity and safety, including selenium nanoparticles and metallic nanoparticles Practical discussions of nanotoxicology and drug delivery, including gene delivery using nanocarriers and the use of nanomaterials for ocular delivery applications In-depth examinations of nanotechnology ethics and the regulatory framework of nanotechnology and medicine Perfect for researchers, post-doctoral candidates, and specialists in the fields of nanotechnology, nanomaterials, and nanocarriers, Nanotechnology in Medicine: Toxicity and Safety will also prove to be an indispensable part of the libraries of nanoengineering, nanomedicine, and biopharmaceutical professionals and nanobiotechnologists.