Advanced Drug Formulation Design To Optimize Therapeutic Outcomes
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Author | : Robert O. Williams |
Publisher | : CRC Press |
Total Pages | : 536 |
Release | : 2007-09-25 |
Genre | : Medical |
ISBN | : 9781420043877 |
This title demonstrates how advanced formulation designs and delivery technologies can be used to improve drug efficacy and treatment outcomes in particular therapeutic categories or disease states. It discusses nanoparticle systems for cancer treatments, and also presents cutting edge immono-regulation agents for transplantation and the local targeting of drugs, especially poorly water soluble drugs to provide enhanced therapeutic outcomes. In addition, this title highlights areas of therapy showing the most promise for improvement in clinical outcomes via advanced formulation design.
Author | : Robert O. Williams |
Publisher | : CRC Press |
Total Pages | : 532 |
Release | : 2007-09-25 |
Genre | : Medical |
ISBN | : 1420043889 |
This title demonstrates how advanced formulation designs and delivery technologies can be used to improve drug efficacy and treatment outcomes in particular therapeutic categories or disease states. It discusses nanoparticle systems for cancer treatments, and also presents cutting edge immono-regulation agents for transplantation and the local targ
Author | : Gilles Grateau |
Publisher | : CRC Press |
Total Pages | : 576 |
Release | : 2004-11-29 |
Genre | : Medical |
ISBN | : 1420037498 |
This authoritative volume contains 179 chapters by international experts on recent developments in our understanding of amyloid proteins, protein folding disorders, and new and proposed clinical trials in amyloidosis. Topics include detection and characterization techniques; biological functions; genetics; disorders, diagnosis, and treatments, incl
Author | : Kamal Dua |
Publisher | : Elsevier |
Total Pages | : 574 |
Release | : 2021-06-24 |
Genre | : Science |
ISBN | : 0323900798 |
Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. - Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer - Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers - Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems
Author | : Mariko Morishita |
Publisher | : CRC Press |
Total Pages | : 488 |
Release | : 2016-04-19 |
Genre | : Medical |
ISBN | : 1420086715 |
Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development presents the work of an international group of leading experts in drug development and biopharmaceutical science who discuss the latest advances in biodrug delivery systems and associated techniques. The book discusses components of successful formulation, delivery, and p
Author | : Ramakrishna Seethala |
Publisher | : CRC Press |
Total Pages | : 504 |
Release | : 2016-04-19 |
Genre | : Medical |
ISBN | : 1420061690 |
Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery. With extensively updated content and 21 new chapters, this text examines:quality and efficiency of drug target validati
Author | : Richard A. Guarino |
Publisher | : CRC Press |
Total Pages | : 550 |
Release | : 2016-04-19 |
Genre | : Medical |
ISBN | : 1420088505 |
The thoroughly revised Fifth Edition of New Drug Approval Process supplies readers with the latest global changes that affect pharmaceutical product approval and influence how new products are researched and marketed.Updated chapters include:advances in international regulatory requirements, including ICH guidelines and harmonizationa step-by-step
Author | : A. David Rodrigues |
Publisher | : CRC Press |
Total Pages | : 769 |
Release | : 2019-01-03 |
Genre | : Medical |
ISBN | : 0849375940 |
Authored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical, clinical, toxicological, and regulatory perspectives.Thoroughly updated, this second edition reflects the significant advances and includes extensive new material on:key interplay between transporters and enzymes
Author | : Martin D. Hynes |
Publisher | : CRC Press |
Total Pages | : 310 |
Release | : 2016-04-19 |
Genre | : Medical |
ISBN | : 1000654370 |
This Second Edition is an essential guide to preparing for FDA pre-approval inspections-taking into account current trends in FDA expectations and inspection activities, such as the GMPs of the 21st Century, quality systems-based approach to inspections, risk-based inspections, quality by design, process analytical technology, design space, etc. Th
Author | : Anthony Kennedy |
Publisher | : CRC Press |
Total Pages | : 274 |
Release | : 2008-03-17 |
Genre | : Medical |
ISBN | : 104006292X |
Encompassing the full spectrum of project management's role and responsibility encountered in the pharmaceutical industry, Pharmaceutical Project Management outlines the key objectives, risks, and challenges of each stage of the pharmaceutical lifecycle, from discovery and preclinical phases through clinical development, manufacturing, registration