Molecular Neuropathology

Molecular Neuropathology
Author: Gareth W. Roberts
Publisher: Cambridge University Press
Total Pages: 204
Release: 1995-06-08
Genre: Medical
ISBN: 9780521425582

This volume provides an introduction to the essential techniques required for studying the molecular biology of brain disease. The approaches and strategies for investigations of gene structure and regulation are described with reference to the molecular genetics of prion and Alzheimer's disease. The effects of aberrant gene regulation can also be examined at the protein level by immunocytochemistry and autoradiography. Improved understanding of basic biology has resulted in new approaches to animal models using transgenic techniques and new therapeutic approaches. The volume is structured to illustrate all these approaches and demonstrate the practice and promise of molecular neuropathology.

Neuropathology of Neurodegenerative Diseases

Neuropathology of Neurodegenerative Diseases
Author: Gabor G. Kovacs
Publisher: Cambridge University Press
Total Pages: 320
Release: 2017-12-13
Genre: Medical
ISBN: 1316337650

This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases.

Current Catalog

Current Catalog
Author: National Library of Medicine (U.S.)
Publisher:
Total Pages: 1568
Release:
Genre: Medicine
ISBN:

First multi-year cumulation covers six years: 1965-70.

WHO Classification of Tumours of the Central Nervous System

WHO Classification of Tumours of the Central Nervous System
Author: David N. Louis
Publisher: World Health Organization
Total Pages: 0
Release: 2016
Genre: Central nervous system
ISBN: 9789283244929

WHO Classification of Tumours of the Central Nervous System is the revised fourth edition of the WHO series on histological and genetic typing of human tumors. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 122 authors from 19 countries, contains more than 800 color images and tables, and more than 2800 references. This book is in the series commonly referred to as the "Blue Book" series.

The Neuropathology of Dementia

The Neuropathology of Dementia
Author: Margaret M. Esiri
Publisher: Cambridge University Press
Total Pages: 600
Release: 2004-07-22
Genre: Medical
ISBN: 9780521819152

Completely rewritten and updated, this new edition is almost twice the size of its predecessor. Illustrated in colour throughout, and with contributions from the world's leading authorities, it is the definitive reference on the neuropathology of dementia. It gives practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes: Three entirely new chapters on neuroimaging, molecular diagnostics, and transgenic models. Two chapters on tauopathies under new authorship. A chapter under new authorship on synucleinopathies, which includes multiple system atrophy.

Marsden's Book of Movement Disorders

Marsden's Book of Movement Disorders
Author: Ivan Donaldson
Publisher: Oxford University Press, USA
Total Pages: 1512
Release: 2012-03-29
Genre: Medical
ISBN: 019261911X

Marsden's Book of Movement Disorders covers the full breadth of movement disorders, from the underlying anatomy and understanding of basal ganglia function to the diagnosis and management of specific movement disorders, including the more common conditions such as Parkinson's Disease through to very rare conditions such as Niemann-Pick disease.

Dynamics of Brain Edema

Dynamics of Brain Edema
Author: Hanna M. Pappius
Publisher: Springer Science & Business Media
Total Pages: 456
Release: 2012-12-06
Genre: Medical
ISBN: 3642665241

A workshop on Dynamic Aspects of Cerebral Edema was organized to pro vide an opport~nitY,for interdisciplinary and detailed consideration of this subject, so crucial in neurology and neurosurgery. The previ ous workshops were held in Vienna in 1965 and in Mainz in 1972. In the meantime, our ideas on mechanisms of resolution of cerebral edema had been changing drastically. Controversy had arisen regarding the role of biogenic amines in the development of edema. Active work in several centers had indicated the possibility of a reversible compo nent in edematous changes associated with ischemia, the control of which could be of therapeutic significance in the problem of stroke. It was felt that a thorough discussion, at this time, by those involv ed in these various studies should help to resolve the controversies, to crystallize the implications of the new findings, and to evaluate their application for patient care. In preparing the proceedings for publication we have edited the manu scripts and selected the discussions with an aim to highlight new find ings, to make this volume readable, and to eliminate duplication. We gratefully acknowledge financial support from the institutions and organizations previously listed. Many individuals contributed to the success of the workshop and the preparation of the proceedings for publication. Doctors J.B. Brierley, I. Klatzo, H.J. Reulen, and A.G.

Autonomic Failure

Autonomic Failure
Author: Christopher J. Mathias
Publisher: OUP Oxford
Total Pages: 922
Release: 2013-06-13
Genre: Medical
ISBN: 0198566344

This new edition makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, and continues to provide practitioners from a variety of fields with a rational guide to aid in the recognition and management of autonomic disorders.