Ketamine

Ketamine
Author:
Publisher:
Total Pages: 187
Release: 2020
Genre: Ketamine
ISBN: 9789811529030

This book presents the latest data from basic research and clinical trials supporting the effectiveness of ketamine as a treatment for depression, bipolar disorder, and suicidal behavior, setting these positive findings within the context of the serious problem of ketamine abuse. The first part of the book focuses on the evidence regarding ketamine abuse, with specific reference to Asian countries, and discusses countermeasures and complication management. It then addresses the mechanisms underlying the antidepressant and side effects of ketamine, which have remained elusive, describing and discussing important new research findings. Further, it explains insights gained from whole brain imaging in rodents and from behavioral pharmacology, and presents evidence regarding the role of gut microbiota, the NMDA receptor GluN2D subunit, and the lateral habenula in the actions of ketamine. These advances form the basis for the safer use of ketamine in patients with treatment-resistant depression and are expected to lead to the development of new antidepressants. --

Attention and Time

Attention and Time
Author: Kia Nobre
Publisher:
Total Pages: 478
Release: 2010
Genre: Medical
ISBN: 0199563454

Our ability to attend selectively to our surroundings - taking notice of the things that matter, and ignoring those that don't - is crucial if we are to negotiate the world around us in an efficient manner. Several aspects of the temporal dimension turn out to be critical in determining how we can put together and select the events that are important to us as they themselves unfold over time. For example, we often miss events that happen while we are occupied perceiving or responding to another stimulus. On the other hand, temporal regularity between events can also greatly improve our perception. In addition, our perception of the passage of time itself can also be distorted as while we are performing actions or paying attention to different aspects of the environment. Surprisingly, this fascinating and fundamental interplay between ' attention' and 'time' has been relatively neglected in the psychology and neuroscience literatures until very recently. Attention & Time is the first book to address this foundational topic, bringing together several intriguing and hitherto fragmented findings into a compelling and cohesive field of enquiry. The book contains thirty-one critical-review chapters from internationally recognised experts in the field, carefully organised into three stand-alone, yet extensively cross-referenced, themed sections. Each section focuses on distinct ways in which attention and time influence one another. These sections, each encompassing a range of methodologies from classical cognitive psychology to single-cell neurophysiology, provide functionally unifying frameworks to help guide the reader through the many various experimental and theoretical approaches adopted. Section 1 considers variations of attention across time, and explores how attentional allocation is limited by very short or very long intervals of time. Section 2 describes several types of temporal illusion, illustrating how attention can modulate the perception of the passage of time itself. "A watched pot never boils" and, conversely, "time flies when you're having fun" nicely capture the experimental observation that the degree of attention allocated to stimulus timing contributes to its subjective duration. Finally, Section 3 examines how attention can be directed in time, to predictable or expected moments in time, so as to optimise behaviour. Bringing conceptually discrete, yet functionally related, fields of temporal attention research together within a single volume, this book provides a comprehensive overview that will be of value to the interested novice in cognitive neuroscience, whilst also inspiring experts in the field to make, perhaps previously overlooked, links with their own field of research.

The Growing Spine

The Growing Spine
Author: Behrooz A. Akbarnia
Publisher: Springer Science & Business Media
Total Pages: 624
Release: 2010-12-31
Genre: Medical
ISBN: 3540852077

Spinal disorders in very young children may be caused by a variety of conditions. The treatment of such conditions is often challenging due to the age of the patient and the progressive nature of the deformity. There also may be associated problems such as congenital anomalies, respiratory insufficiency, and neurological problems. Depending on the etiology of the deformity, these children are often cared for by multiple specialists including pediatricians, pediatric orthopaedists or orthopaedic spine surgeons, neurologists, pediatric surgeons, pediatric neurosurgeons, oncologists, and/or pulmonologists. Health professionals in all of the mentioned disciplines are involved in the management of these patients, which is why compiling a comprehensive textbook that is not limited to orthopedic specialists is essential. This textbook will effectively help to standardize the care of these patients. Furthermore, other professionals such as nurses, physical therapists and healthcare professionals in training are usually not familiar with these conditions and are in need of a reference book to consult when caring for children with spinal deformities.

Brain Banking

Brain Banking
Author:
Publisher: Elsevier
Total Pages: 448
Release: 2018-02-27
Genre: Medical
ISBN: 0444636420

Brain Banking, Volume 150, serves as the only book on the market offering comprehensive coverage of the functional realities of brain banking. It focuses on brain donor recruitment strategies, brain bank networks, ethical issues, brain dissection/tissue processing/tissue dissemination, neuropathological diagnosis, brain donor data, and techniques in brain tissue analysis. In accordance with massive initiatives, such as BRAIN and the EU Human Brain Project, abnormalities and potential therapeutic targets of neurological and psychiatric disorders need to be validated in human brain tissue, thus requiring substantial numbers of well characterized human brains of high tissue quality with neurological and psychiatric diseases. - Offers comprehensive coverage of the functional realities of brain banking, with a focus on brain donor recruitment strategies, brain bank networks, ethical issues, and more - Serves as a valuable resource for staff in existing brain banks by highlighting best practices - Enhances the sharing of expertise between existing banks and highlights a range of techniques applicable to banked tissue for neuroscience researchers - Authored by leaders from brain banks around the globe – the broadest, most expert coverage available

Genome Structure and Function

Genome Structure and Function
Author: C. Nicolini
Publisher: Springer Science & Business Media
Total Pages: 358
Release: 1997-05-31
Genre: Science
ISBN: 9780792345657

Proceedings of the NATO Advanced Study Institute on Genome Structure and Function, held in Marciana Marina, Elba, Italy, 13-23 June 1996