A Textbook Of Modern Pharmacology And Toxicology
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Author | : Dr. Satyendra Kumar Kashyap |
Publisher | : AG PUBLISHING HOUSE (AGPH Books) |
Total Pages | : 259 |
Release | : 2023-02-17 |
Genre | : Study Aids |
ISBN | : 8119025865 |
Clinical Pharmacology & Toxicology refers to the study of pharmaceuticals in people. To that end, clinical pharmacologists focus on both improving the effectiveness of already available medications and creating brand new ones. In light of the thalidomide disaster, contemporary clinical pharmacology was born, yet nowadays, most adverse medication responses are dosage related. To begin with, doctors would utilise TDM to adjust a patient's dose based on their specific needs. In recent years, pharmacogenetics has been employed for this, and it has also proven helpful in selecting appropriate medications. Understanding how medications are absorbed, distributed, and excreted (pharmacokinetics) has allowed for advancements in this field. Evaluation of renal function and clarification of the pharmacokinetic implications of compromised renal function have been at the heart of this work. Clinical toxicology is a branch of toxicology that deals with the care of poisoned patients at the bedside. This includes making a definitive toxicological diagnosis, figuring out how bad the poisoning is right now and what the long-term outlook is, and choosing treatments, including antidotes. A clinical toxicologist's expertise in the possible dangers of drugs and chemicals enables them to aid in the prevention and preparation of chemical overdoses. Clinical disease is mostly brought on by toxicants. Because of this, clinical toxicology is included in internal medicine and greatly benefits from the expertise of other medical fields. Clinical toxicology calls for expert knowledge of pharmacology.
Author | : Alan Woolf |
Publisher | : Academic Press |
Total Pages | : 648 |
Release | : 2021-10-13 |
Genre | : Medical |
ISBN | : 0128222190 |
History of Modern Clinical Toxicology describes the extraordinary advances in the practice of clinical toxicology within the past 70 years and brings together stories of the people – the champions of clinical toxicology - who contributed to these advances, discovered new therapies and antidotes, and made change happen. This book lays out the poison control system they built and the fascinating story of how they created a new and evolving medical specialty. With the participation of renowned international experts as authors, the book showcases the development of poison control centers around the world and the growth of the professional societies that represent and support them today. This book also tells the stories of the modern-day toxic disasters and recent toxic exposures that gained worldwide attention and notoriety. It outlines the public health responses to such calamities which have led to improvements in our understanding of the science and changes in public health policies and regulations to forestall future such events. Finally, the book covers key policies and agencies affecting poison control centers, addresses the challenges facing clinical toxicologists of today, and predicts advances and future innovations in the field. History of Modern Clinical Toxicology is a unique resource that provides the historical and international perspective that will help students, practitioners, scientists, and health policy makers put current issues and methods in perspective. It will help them understand how infrastructure and processes in clinical toxicology have evolved and why poison control systems are configured as they are. - Offers descriptions of the key regulatory advances affecting clinical toxicology - Provides synopses of modern-day poisoning disasters - Outlines the development of modern antidotes and future directions in clinical toxicology - Describes the origins and development of the U.S. poison control system - Includes the origins and features of professional clinical toxicology societies from around the world - Includes descriptions of the history of clinical toxicology and poison control in more than 35 countries
Author | : Ernest Hodgson |
Publisher | : McGraw-Hill Medical Publishing |
Total Pages | : 518 |
Release | : 1997 |
Genre | : Medical |
ISBN | : |
This revised edition reflects changes in the core curriculum subjects covered in the basic toxicology course for graduate students. Designed as an introductory textbook, it emphasizes the fundamental basis of toxic action at the cellular and molecular levels and lays the foundation for specialized courses in toxicology. Additional topics include metabolic activation and cellular protection, clinical toxicology diagnosis and treatment, ecosystems, environmental toxicology, ecotoxicology, case histories, and future consideration for environmental and human health.
Author | : Philip C. Burcham |
Publisher | : Springer Science & Business Media |
Total Pages | : 338 |
Release | : 2013-11-19 |
Genre | : Medical |
ISBN | : 144715553X |
This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960’s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text.
Author | : Andreas Luch |
Publisher | : Springer Science & Business Media |
Total Pages | : 620 |
Release | : 2010-03-01 |
Genre | : Medical |
ISBN | : 3764383380 |
Clinical Toxicology is the second volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.
Author | : John Joseph Fenton |
Publisher | : CRC Press |
Total Pages | : 585 |
Release | : 2001-10-10 |
Genre | : Law |
ISBN | : 1420042068 |
REAL-LIFE CASES, TUTORIAL QUESTIONS, NARRATIVE HISTORY Intriguing anecdotal pedagogy, like the alleged arsenical poisonings of Napoleon and President Taylor and the probable mercury overdose of Isaac Newton, is one of the things that set Toxicology: A Case-Oriented Approach apart from other toxicology texts. Based on an undergraduate-graduat
Author | : Abialbon Paul |
Publisher | : Springer Nature |
Total Pages | : 1156 |
Release | : 2021-03-13 |
Genre | : Medical |
ISBN | : 9813360097 |
This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.
Author | : Curtis D. Klaassen |
Publisher | : McGraw-Hill Book Company Limited |
Total Pages | : 912 |
Release | : 1996 |
Genre | : Medical |
ISBN | : 9780071139274 |
This updated and revised edition delineates the basic concepts and fundamental principles needed to grasp current issues in modern toxicology. In addition, new contributions help to redefine the book's scope and coverage, and illuminate new and emerging areas of toxicologic interest.
Author | : Ernest Hodgson |
Publisher | : John Wiley & Sons |
Total Pages | : 601 |
Release | : 2011-09-20 |
Genre | : Science |
ISBN | : 1118211294 |
A Textbook of Modern Toxicology is a unique resource that provides both students and practitioners with a wide-ranging, accessible overview of the discipline. Suitable for courses in environmental, pharmacological, medical, and veterinary toxicology, this essential text features chapters written by experts who address a range of key topics. The Fourth Edition includes additional chapters on new approaches to toxicology - molecular methods (-omics: toxicogenomics, proteomics, and metabolomics), bioinformatics, and systems biology – and continues the legacy of its predecessors to provide up-to-date insights into acute toxicity and chemical carcinogenesis, organ toxicity, in vitro and in vivo toxicity testing, ecological risk assessment, and many other areas of toxicology that help foster a solid comprehension of the field. Also featured in the Fourth Edition are end-of-chapter questions and a Solutions Manual available separately for academic adopters.
Author | : Pillay |
Publisher | : JAYPEE BROTHERS PUBLISHERS |
Total Pages | : 632 |
Release | : 2012-11-30 |
Genre | : Medical |
ISBN | : 9350259656 |