A Quantitative MRI Study of Prostate Cancer Before and After Radiation Therapy

A Quantitative MRI Study of Prostate Cancer Before and After Radiation Therapy
Author:
Publisher:
Total Pages: 12
Release: 2003
Genre:
ISBN:

The purpose of the study was to examine the influence of external beam radiation on the prostate and prostate cancer using novel quantitative MRI techniques. Twenty-two men, previously diagnosed with prostate cancer, were studied using T1 and T2 relaxation mapping and contrast agent kinetic methods before and after treatment by radiotherapy. The MRI findings will be correlated with biochemical (prostate specific antigen) progression and biopsy results. All 22 patients have been recruited and studied pre-treatment. So far nineteen patients have returned for follow-up MRI. The data is both complete and of a high quality. Data analysis of the pre-treatment phase has provided important and novel information about the microvascular characteristics of prostate cancer. These results have been accepted for publication in the leading radiology journal. Preliminary analysis of the post- treatment data is promising and awaits clinical interpretation.

Adaptive Radiation Therapy

Adaptive Radiation Therapy
Author: X. Allen Li
Publisher: CRC Press
Total Pages: 404
Release: 2011-01-27
Genre: Medical
ISBN: 1439816352

Modern medical imaging and radiation therapy technologies are so complex and computer driven that it is difficult for physicians and technologists to know exactly what is happening at the point-of-care. Medical physicists responsible for filling this gap in knowledge must stay abreast of the latest advances at the intersection of medical imaging an

Quantitative MRI in Cancer

Quantitative MRI in Cancer
Author: Thomas E. Yankeelov
Publisher: Taylor & Francis
Total Pages: 331
Release: 2011-09-13
Genre: Medical
ISBN: 1439820589

Propelling quantitative MRI techniques from bench to bedside, Quantitative MRI in Cancer presents a range of quantitative MRI methods for assessing tumor biology. It includes biophysical and theoretical explanations of the most relevant MRI techniques as well as examples of these techniques in cancer applications.The introductory part of the book c

Radioguided Surgery

Radioguided Surgery
Author: Giuliano Mariani
Publisher: Springer Science & Business Media
Total Pages: 319
Release: 2010-05-10
Genre: Medical
ISBN: 0387383271

This multidisciplinary textbook is designed to be the standard on the subject and is geared for use by physicians who are involved in the care and/or diagnosis of cancer patients. Comprehensive coverage is provided on all aspects of radioguided surgery. Practical information is readily accessible and throughout there is an emphasis on improved decision making. Tables present the indications, performance, and interpretation of procedures at a glance. A wealth of illustrations, including a full-color insert, enhances the application of new concepts.

MRI for Radiotherapy

MRI for Radiotherapy
Author: Gary Liney
Publisher: Springer
Total Pages: 210
Release: 2019-06-20
Genre: Medical
ISBN: 3030144429

This book provides, for the first time, a unified approach to the application of MRI in radiotherapy that incorporates both a physics and a clinical perspective. Readers will find detailed information and guidance on the role of MRI in all aspects of treatment, from dose planning, with or without CT, through to response assessment. Extensive coverage is devoted to the latest technological developments and emerging options. These include hybrid MRI treatment systems, such as MRI-Linac and proton-guided systems, which are ushering in an era of real-time MRI guidance. The past decade has witnessed an unprecedented rise in the use of MRI in the radiation treatment of cancer. The development of highly conformal dose delivery techniques has led to a growing need to harness advanced imaging for patient treatment. With its flexible soft tissue contrast and ability to acquire functional information, MRI offers advantages at all stages of treatment. In documenting the state of the art in the field, this book will be of value to a wide range of professionals. The authors are international experts drawn from the scientific committee of the 2017 MR in RT symposium and the faculty of the ESTRO teaching course on imaging for physicists.

Machine Learning in Radiation Oncology

Machine Learning in Radiation Oncology
Author: Issam El Naqa
Publisher: Springer
Total Pages: 336
Release: 2015-06-19
Genre: Medical
ISBN: 3319183052

​This book provides a complete overview of the role of machine learning in radiation oncology and medical physics, covering basic theory, methods, and a variety of applications in medical physics and radiotherapy. An introductory section explains machine learning, reviews supervised and unsupervised learning methods, discusses performance evaluation, and summarizes potential applications in radiation oncology. Detailed individual sections are then devoted to the use of machine learning in quality assurance; computer-aided detection, including treatment planning and contouring; image-guided radiotherapy; respiratory motion management; and treatment response modeling and outcome prediction. The book will be invaluable for students and residents in medical physics and radiation oncology and will also appeal to more experienced practitioners and researchers and members of applied machine learning communities.

Bone Metastases from Prostate Cancer

Bone Metastases from Prostate Cancer
Author: Francesco Bertoldo
Publisher: Springer
Total Pages: 293
Release: 2016-11-07
Genre: Medical
ISBN: 3319423274

This book presents up-to-date information on one of the hottest topics in prostate cancer, namely bone metastases. The most recent developments with respect to biology, pathology, diagnosis, and treatment are described, providing readers with an excellent understanding of the mechanisms of metastasis formation, the characteristics of metastases, their aggressiveness, and prognostic factors for treatment response. The coverage includes discussion of all of the best available options (laboratory, radiology, and nuclear medicine) for achieving early diagnosis and both established and novel therapeutic approaches. Detailed information is provided on hormonal manipulations, bone-targeted agents, vaccines, taxanes, and other treatments that are enriching the therapeutic armamentarium. The editors can be considered leaders in the field, with great experience in diagnostic and clinical oncology and research, and the authors are experts in diverse specialties. This ensures a multidisciplinary approach, mirroring the current situation in which treatment in patients with bone metastases is undertaken by a team of specialists and health professionals in a variety of fields.

Radiomics and Radiogenomics

Radiomics and Radiogenomics
Author: Ruijiang Li
Publisher: CRC Press
Total Pages: 420
Release: 2019-07-09
Genre: Science
ISBN: 1351208268

Radiomics and Radiogenomics: Technical Basis and Clinical Applications provides a first summary of the overlapping fields of radiomics and radiogenomics, showcasing how they are being used to evaluate disease characteristics and correlate with treatment response and patient prognosis. It explains the fundamental principles, technical bases, and clinical applications with a focus on oncology. The book’s expert authors present computational approaches for extracting imaging features that help to detect and characterize disease tissues for improving diagnosis, prognosis, and evaluation of therapy response. This book is intended for audiences including imaging scientists, medical physicists, as well as medical professionals and specialists such as diagnostic radiologists, radiation oncologists, and medical oncologists. Features Provides a first complete overview of the technical underpinnings and clinical applications of radiomics and radiogenomics Shows how they are improving diagnostic and prognostic decisions with greater efficacy Discusses the image informatics, quantitative imaging, feature extraction, predictive modeling, software tools, and other key areas Covers applications in oncology and beyond, covering all major disease sites in separate chapters Includes an introduction to basic principles and discussion of emerging research directions with a roadmap to clinical translation

Quantitative MRI of the Brain

Quantitative MRI of the Brain
Author: Paul Tofts
Publisher: John Wiley & Sons
Total Pages: 650
Release: 2005-08-19
Genre: Medical
ISBN: 0470869496

2004 BMA Medical Book Competition Winner (Radiology category) “This is an exciting book, with a new approach to use of the MRI scanner. It bridges the gap between clinical research and general neuro-radiological practice. It is accessible to the clinical radiologist, and yet thorough in its treatment of the underlying physics and of the science of measurement. It is likely to become a classic.” British Medical Association This indispensable 'how to' manual of quantitative MR is essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological disease, its progression, and its response to treatment. It contains both the methodology and clinical applications, reflecting the increasing interest in quantitative MR in studying disease and its progression. The editor is an MR scientist with an international reputation for high quality research The contributions are written jointly by MR physicists and MR clinicians, producing a practical book for both the research and medical communities A practical book for both the research and medical communities “Paul Tofts has succeeded brilliantly in capturing the essence of what needs to become the future of radiology in particular, and medicine in general – quantitative measurements of disease.” Robert I. Grossman, M.D. New York, University School of Medicine (from the Foreword)