A New Model for Analyzing Antimicrobial Peptides with Biomedical Applications

A New Model for Analyzing Antimicrobial Peptides with Biomedical Applications
Author: Edwin Lowell Cooper
Publisher: IOS Press
Total Pages: 216
Release: 2002
Genre: Medical
ISBN: 9781586032371

Annotation This book is aimed at two audiences. First, it will present evidence for the earthworm's immune system. Second, the results strongly suggest that certain molecules of the earthworm's immune system may be exploited as natural antibiotics--thus the biomedical applications. There are two advantages for using earthworms. First, they are an inexpensive, non-controversial invertebrate model. Second, in contrast to other invertebrates (e.g. Drosophila, C elegans) they are essential for maintaining the integrity of soil. Earthworms have a highly effective immune system since cancer cannot be induced in them nor does it seem to occur in natural populations. Cytotoxicity of cancer cells has been examined in relation to two earthworm leukocytes based upon: structure; cell differentiation antigens; function revealed by FACS and mAbs. These cells are SMALL (8-11 m) electron dense (SC), positive for human cell adhesion molecules (CD11a, CD45RA, CD45RO, CDw49b, CD54, for?2-microglobulin and for Thy-1; LARGE (12-15 m) electron lucent cells (LC), negative for these same markers. Leukocytes synthesize and secrete lytic molecules (fetidins, CCF-1, lysenin, eiseniapore) participate in recognition of, binding to, killing and sequestration of cancer cells in vitro. Earthworm lytic levels are significantly higher than those of human NK cells. Earthworms possess a highly evolved, unique and efficient immune system that has facilitated long-term survival.

Prokaryotic Antimicrobial Peptides

Prokaryotic Antimicrobial Peptides
Author: Djamel Drider
Publisher: Springer Science & Business Media
Total Pages: 451
Release: 2011-03-08
Genre: Science
ISBN: 1441976922

The book will provide an overview of the advancement of fundamental knowledge and applications of antimicrobial peptides in biomedical, agricultural, veterinary, food, and cosmetic products. Antimicrobial peptides stand as potentially great alternatives to current antibiotics, and most research in this newly-created area has been published in journals and other periodicals. It is the editors’ opinion that it is timely to sum up the most important achievements in the field and provide the scientific community in a reference book. The goals of this project include illustrating the achievements made so far, debating the state of the art, and drawing new perspectives.

Antimicrobial Peptides

Antimicrobial Peptides
Author: Katsumi Matsuzaki
Publisher: Springer
Total Pages: 304
Release: 2019-04-12
Genre: Medical
ISBN: 9811335885

This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.

Prokaryotic Antimicrobial Peptides

Prokaryotic Antimicrobial Peptides
Author: Djamel Drider
Publisher: Springer
Total Pages: 451
Release: 2011-03-08
Genre: Science
ISBN: 9781441976918

The book will provide an overview of the advancement of fundamental knowledge and applications of antimicrobial peptides in biomedical, agricultural, veterinary, food, and cosmetic products. Antimicrobial peptides stand as potentially great alternatives to current antibiotics, and most research in this newly-created area has been published in journals and other periodicals. It is the editors’ opinion that it is timely to sum up the most important achievements in the field and provide the scientific community in a reference book. The goals of this project include illustrating the achievements made so far, debating the state of the art, and drawing new perspectives.

Biomedical Engineering

Biomedical Engineering
Author: Sylwia Olsztynska
Publisher: IntechOpen
Total Pages: 658
Release: 2011-01-08
Genre: Medical
ISBN: 9789533075143

This book is addressed to scientists and professionals working in the wide area of biomedical engineering, from biochemistry and pharmacy to medicine and clinical engineering. The panorama of problems presented in this volume may be of special interest for young scientists, looking for innovative technologies and new trends in biomedical engineering.

Microbial Functional Foods and Nutraceuticals

Microbial Functional Foods and Nutraceuticals
Author: Vijai Kumar Gupta
Publisher: John Wiley & Sons
Total Pages: 327
Release: 2017-10-30
Genre: Technology & Engineering
ISBN: 1119048974

Showcases the recent advances in microbial functional food applications across food science, microbiology, biotechnology, and chemical engineering Microbial technology plays a key role in the improvement of biotechnology, cosmeceuticals, and biopharmaceutical applications. It has turned into a subject of expanding significance because new microbes and their related biomolecules are distinguished for their biological activity and health benefits. Encompassing both biotechnology and chemical engineering, Microbial Functional Foods and Nutraceuticals brings together microbiology, bacteria, and food processing/mechanization, which have applications for a variety of audiences. Pharmaceuticals, diagnostics, and medical device development all employ microbial food technology. The book addresses the recent advances in microbial functional foods and associated applications, providing an important reference work for graduates and researchers. It also provides up-to-date information on novel nutraceutical compounds and their mechanisms of action—catering to the needs of researchers and academics in food science and technology, microbiology, chemical engineering, and other disciplines who are dealing with microbial functional foods and related areas. Microbial Functional Foods and Nutraceuticals is: Ground-breaking: Includes the latest developments and research in the area of microbial functional foods and nutraceuticals Multidisciplinary: Applicable across food science and technology, microbiology, biotechnology, chemical engineering, and other important research fields Practical and academic: An important area of both academic research and new product development in the food and pharmaceutical industries Microbial Functional Foods and Nutraceuticals is an ideal resource of information for biologists, microbiologists, bioengineers, biochemists, biotechnologists, food technologists, enzymologists, and nutritionists.

Environmental Pollution

Environmental Pollution
Author: Rachel H. Plattenberg
Publisher: Nova Publishers
Total Pages: 324
Release: 2007
Genre: Nature
ISBN: 9781600212857

Pollution is the release of chemical, physical, biological or radioactive contaminants to the environment. Principal forms of pollution include: air pollution, the release of chemicals and particulates into the atmosphere. Common examples include carbon monoxide, sulphur dioxide, chlorofluorocarbons (CFCs), and nitrogen oxides produced by industry and motor vehicles. Ozone and smog are created as nitrogen oxides and hydrocarbons react to sunlight. Water pollution affects oceans and inland bodies of water. Examples include organic and inorganic chemicals, heavy metals, petrochemicals, chloroform, and bacteria. Water pollution may also occur in the form of thermal pollution and the depletion of dissolved oxygen. Soil contamination often occurs when chemicals are released by spill or underground storage tank leakage. Contaminants include hydrocarbons, heavy metals, MTBE, herbicides, pesticides and chlorinated hydrocarbons. Often occurs with water pollution, thanks to surface runoff and groundwater. Radioactive contamination was added in the wake of 20th-century discoveries in atomic physics. Noise pollution encompasses roadway noise, aircraft noise, industrial noise as well as high-intensity sonar. Light pollution, includes light trespass, over-illumination and astronomical interference. Visual pollution, which can refer to the presence of overhead power lines, highway billboards, scarred landforms (as from strip mining), open storage of junk or municipal solid waste. The nature, distribution and ecological effects of all types and forms of pollutants in air, soil and water are the subject of this book.

Peptide Applications in Biomedicine, Biotechnology and Bioengineering

Peptide Applications in Biomedicine, Biotechnology and Bioengineering
Author: Sotirios Koutsopoulos
Publisher: Woodhead Publishing
Total Pages: 655
Release: 2017-11-16
Genre: Technology & Engineering
ISBN: 0081007426

Peptide Applications in Biomedicine, Biotechnology and Bioengineering summarizes the current knowledge on peptide applications in biomedicine, biotechnology and bioengineering. After a general introduction to peptides, the book addresses the many applications of peptides in biomedicine and medical technology. Next, the text focuses on peptide applications in biotechnology and bioengineering and reviews of peptide applications in nanotechnology. This book is a valuable resource for biomaterial scientists, polymer scientists, bioengineers, mechanical engineers, synthetic chemists, medical doctors and biologists. Presents a self-contained work for the field of biomedical peptides Summarizes the current knowledge on peptides in biomedicine, biotechnology and bioengineering Covers current and potential applications of biomedical peptides