99mTc-Sestamibi

99mTc-Sestamibi
Author: Jan Bucerius
Publisher: Springer Science & Business Media
Total Pages: 203
Release: 2011-09-22
Genre: Medical
ISBN: 3642042333

99mTc-sestamibi is a single-photon emission computed tomography (SPECT) radiotracer that is widely used for the imaging of myocardial perfusion, as well as a variety of malignant and benign diseases. 99mTc-Sestamibi – Clinical Applications provides a detailed and informative overview of almost all the oncologic and non-oncologic applications of 99mTc-sestamibi SPECT, including several relatively rare indications. Different disease-related protocols for 99mTc-sestamibi SPECT are presented, and for each disease a comprehensive summary of the relevant pathology and epidemiology is provided. Throughout, there is a strong emphasis on the practical aspects of use of this popular tracer, including instructions for the preparation of several commercially available tracer kits. Clinical practitioners will find this book to be an invaluable guide to the application and benefits of 99mTc-sestamibi SPECT in both the inpatient and the outpatient setting.

Cardiac SPECT Imaging

Cardiac SPECT Imaging
Author: E. Gordon DePuey
Publisher: Lippincott Williams & Wilkins
Total Pages: 366
Release: 2001
Genre: Medical
ISBN: 9780781720076

Cardiac SPECT Imaging, Second Edition offers the best of all possible worlds--a critical topic, internationally recognized authors and cutting-edge coverage. It guides you through all aspects of the modality--from basic principles (acquiring and processing images, quality control)...and clinical applications (evaluating myocardial infarction and coronary artery disease)...to the very latest equipment. It even compares SPECT with other modalities (PET, CT, MRI, and echocardiography) to ensure smart, cost-effective decisions by both the cardiologist and nuclear medicine physician.Look for new chapters on attenuation correction, gated perfusion SPECT, radiopharmaceuticals, and myocardial perfusion SPECT, as well as the very latest on myocardial perfusion SPECT in conjunction with exercise and pharmacologic stress, assessment of perfusion/viability with Tc-99m agents, how SPECT compares with other advanced cardiac imaging modalities, and more!

Technetium-99m Pharmaceuticals

Technetium-99m Pharmaceuticals
Author: Ilse Zolle
Publisher: Springer Science & Business Media
Total Pages: 354
Release: 2007-01-28
Genre: Medical
ISBN: 3540339906

Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.

Radioguided Surgery

Radioguided Surgery
Author: Giuliano Mariani
Publisher: Springer Science & Business Media
Total Pages: 319
Release: 2010-05-10
Genre: Medical
ISBN: 0387383271

This multidisciplinary textbook is designed to be the standard on the subject and is geared for use by physicians who are involved in the care and/or diagnosis of cancer patients. Comprehensive coverage is provided on all aspects of radioguided surgery. Practical information is readily accessible and throughout there is an emphasis on improved decision making. Tables present the indications, performance, and interpretation of procedures at a glance. A wealth of illustrations, including a full-color insert, enhances the application of new concepts.

Handbook of Radiopharmaceuticals

Handbook of Radiopharmaceuticals
Author: Michael R. Kilbourn
Publisher: John Wiley & Sons
Total Pages: 768
Release: 2021-04-12
Genre: Science
ISBN: 1119500540

The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.

Nephrology Forum

Nephrology Forum
Author: J.J. Cohen
Publisher: Springer Science & Business Media
Total Pages: 388
Release: 2012-12-06
Genre: Medical
ISBN: 1461254655

A few years ago, as the editor of Kidney International, I was ap proached by Drs. Cohen, Kassirer, and Harrington who suggested that a new feature should be included in each monthly issue of the journal. They suggested that it should employ a case discussion format such as that used frequently at specialty rounds in teaching hospitals, and that the discussion should place a special emphasis on the relationship between basic science and important problems in clinical nephrology. The summary of an actual patient history would first be presented to exemplify a particular clinical problem, a seasoned person of proven expertise would be invited to deliver a well-documented analysis of the relevant issues, and perhaps most ambitiously of all, a critical audience would be assembled to challenge the principal discussant in an open ended, question-and-answer period. The entire affair would be recorded at the time of the live conference and transcribed subse quently in preparation for publication as a "Nephrology Forum. " I must confess that I was somewhat hesitant at first to endorse their proposal because, at the time, Kidney International had just begun to establish a solid reputation for the publication of high quality, peer reviewed manuscripts dealing with the clinical and laboratory research interests of the international nephrological community.

Molybdenum-99 for Medical Imaging

Molybdenum-99 for Medical Imaging
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 264
Release: 2016-11-28
Genre: Medical
ISBN: 0309445310

The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.

Clinical Gated Cardiac SPECT

Clinical Gated Cardiac SPECT
Author: Guido Germano
Publisher: John Wiley & Sons
Total Pages: 384
Release: 2008-04-15
Genre: Medical
ISBN: 0470987308

"This book will be useful for all physicians involved in cardiac imaging, whether they are in radiology, nuclear medicine, or cardiology, and should be mandatory for physicians engaged in gated cardiac SPECT. It is recommended without reservation." – from a review of the first edition in Radiology With gated cardiac SPECT now firmly established for the management of the cardiac patient, Drs. Germano and Berman bring you completely up to date with the multiple clinical applications as well as the recent technical developments of the modality. Clinical Gated Cardiac SPECT, Second Edition: covers all the available protocols describes a systematic approach for interpretation and reporting provides guidance for the recognition of artifacts includes flowcharts on the management of patients The relationship of gated cardiac SPECT to PET, MRI and CT is explored in separate chapters devoted to each modality. This book is essential reading for all clinicians involved in cardiac imaging.

Handbook of Radiopharmaceuticals

Handbook of Radiopharmaceuticals
Author: Michael R. Kilbourn
Publisher: John Wiley & Sons
Total Pages: 768
Release: 2021-01-05
Genre: Science
ISBN: 1119500559

The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and

Advances in Nuclear Oncology

Advances in Nuclear Oncology
Author: Emilio Bombardieri
Publisher: CRC Press
Total Pages: 534
Release: 2007-10-15
Genre: Medical
ISBN: 0203089677

The diagnostic and therapeutic achievements in radiopharmaceuticals and nuclear medicine instrumentation - PET, SPECT, MR, CT and their hypbrids PET-CT and SPECT-CT - are the result of the interdisciplinary research efforts of cell-biologists, chemists, pharmacologists, physicists, computer-scientists, engineers, nuclear medicine physicians, a